PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
34523337-3	2021	Two fluorinated analogues of RG7388, 6 and 7, were synthesized by attaching a fluoronicotinyl moiety to RG7388 via a polyethylene glycol (PEG3) or a propyl linker.	RG7388	29-35	paternally expressed 3	Mus musculus	138-142
34683929-3	2021	Porphyrin-Micelle (PM), developed by synthesizing porphyrin and PEG-3.5k, confirmed the amplification of the PA agent signal, and added binding affinity in an LNCaP model by attaching prostate-specific membrane antigen PSMA.	Porphyrins	0-9	paternally expressed 3	Mus musculus	64-69
8406595-1	1993	Against lipid A (the conserved moiety of lipopolysaccharides from Gram-negative bacteria) neutralizing IgM monoclonal antibodies (mAb) 8-2 and 26-20 anti-idiotypic (Ab2) mAb were produced: Ab2 mAb KM-04 (IgG1) against mAb 8-2, and Ab2 mAb PW-1 (IgG2a) and PW-2 (IgG1) against mAb 26-20.	Lipid A	8-15	paternally expressed 3	Mus musculus	239-243
34235861-3	2021	One of the MARGs, HA-(PEG 3 -DNP) 8 , showed the best capacity for clustering anti-DNP antibodies onto CD44-positive cancer cells and displayed potent in vitro anti-cancer activity by triggering complement dependent cytotoxicity (CDC) and antibody dependent cell-mediated cytotoxicity (ADCC).	ha	18-20	paternally expressed 3	Mus musculus	22-27
34523337-3	2021	Two fluorinated analogues of RG7388, 6 and 7, were synthesized by attaching a fluoronicotinyl moiety to RG7388 via a polyethylene glycol (PEG3) or a propyl linker.	RG7388	104-110	paternally expressed 3	Mus musculus	138-142
34523337-5	2021	Next, compound 6 was labeled with 18F using a trimethylammonium triflate precursor to obtain (18F)FN-PEG3-RG7388 ((18F)6), and its properties were evaluated in MDM2 expressing wild-type p53 tumor cell lines (SJSA-1 and HepG2) in vitro and in tumor xenografts in vivo.	trimethylammonium triflate	46-72	paternally expressed 3	Mus musculus	101-105
27434113-6	2016	The release profile of enalapril for drug loaded nanoparticles prepared from mPEG3-PCL3 was very fast and release profile for the nanoparticles prepared from mPEG1-PCL1 and mPEG2-PCL2 was sustained.	Enalapril	23-32	paternally expressed 3	Mus musculus	77-82
33980305-11	2021	Prussian blue staining and TEM showed a large amount of iron particles in MTMSCs-PEG3-FTH1 but a minimal amount in MSCs-PEG3-FTH1.	Iron	56-60	paternally expressed 3	Mus musculus	81-85
33574830-4	2020	Liver tissues from mice fed a methionine-choline-deficient (MCD) diet exhibited increased expression of NEAT1 and PEG3 along with lower miR-129-5p expression.	Methionine	30-40	paternally expressed 3	Mus musculus	114-118
33574830-4	2020	Liver tissues from mice fed a methionine-choline-deficient (MCD) diet exhibited increased expression of NEAT1 and PEG3 along with lower miR-129-5p expression.	Choline	41-48	paternally expressed 3	Mus musculus	114-118
31828718-5	2020	Al[18F]F-NOTA-PEG3-duramycin was synthesized via chelation reaction of NOTA-PEG3-duramycin with Al[18F]F.	tetrafluoroaluminate	0-8	paternally expressed 3	Mus musculus	9-18
31828718-5	2020	Al[18F]F-NOTA-PEG3-duramycin was synthesized via chelation reaction of NOTA-PEG3-duramycin with Al[18F]F.	tetrafluoroaluminate	0-8	paternally expressed 3	Mus musculus	71-80
31828718-6	2020	PE-binding capacity of Al[18F]F-NOTA-PEG3-duramycin was determined in a competitive radiometric PE-binding assay.	phosphatidylethanolamine	0-2	paternally expressed 3	Mus musculus	32-41
31828718-10	2020	Compared with the control cells, the binding of Al[18F]F-NOTA-PEG3-duramycin with camptothecin-induced apoptotic cells resulted in a tripling increase.	Camptothecin	82-94	paternally expressed 3	Mus musculus	62-66
31828718-11	2020	A competitive radiometric PE-binding assay strongly confirmed the binding of Al[18F]F-NOTA-PEG3-duramycin to PE.	phosphatidylethanolamine	26-28	paternally expressed 3	Mus musculus	86-95
31828718-13	2020	In the in vivo PET/CT imaging, Al[18F]F-NOTA-PEG3-duramycin demonstrated 2-fold increase in erlotinib-treated HCC827 tumors in nude mice.	erlotinib	92-101	paternally expressed 3	Mus musculus	40-49
31059956-7	2019	RESULTS: BaP exposure reduced the methylation levels in the imprinting genes H19 and Meg3 and increased the methylation levels of Peg1 and Peg3; however, no significant differences was observed for the methylation levels of Igf2 or Snrpn in the sperm DNA.	Benzo(a)pyrene	9-12	paternally expressed 3	Mus musculus	139-143
29037039-8	2017	Overall, we successfully synthesized 18F-PEG3-FPN, which has higher labeling efficacy and better in vivo pharmacokinetics along with lower liver uptake compared to 18F-5-FPN.	N-(2-(diethylamino)ethyl)-5-fluoropicolinamide	164-173	paternally expressed 3	Mus musculus	41-45
29037039-9	2017	This suggests 18F-PEG3-FPN as a candidate for pigmented melanoma liver and lung metastasis detection.	Fluorine-18	14-17	paternally expressed 3	Mus musculus	18-22
28605464-4	2017	This modification is enriched in tetraploid cortical neurons, a cell type where evidence for a small proportion of formylmethylated CpG sites within the Peg3-controlling DMR is also provided.	aspartylmethionylarginine	170-173	paternally expressed 3	Mus musculus	153-157
28654284-2	2017	The radical possesses four mPEG-3 groups replacing four methyl groups in the tert-butyl groups at the 3- and 6-positions of 1,3,6,8-tetra-tert-butyl carbazyl (TTBC).	ttbc	159-163	paternally expressed 3	Mus musculus	27-33
28654284-3	2017	This structure is designed to mitigate the rapid decomposition of the radical via intramolecular 1,5-hydrogen atom transfer (1,5-HAT) that was observed in its constitutional isomer 1-H with four mPEG-3 groups in the vicinity of the nitrogen-centered radical (1- and 8-positions of TTBC).	Hydrogen	101-109	paternally expressed 3	Mus musculus	195-201
28654284-3	2017	This structure is designed to mitigate the rapid decomposition of the radical via intramolecular 1,5-hydrogen atom transfer (1,5-HAT) that was observed in its constitutional isomer 1-H with four mPEG-3 groups in the vicinity of the nitrogen-centered radical (1- and 8-positions of TTBC).	Nitrogen	232-240	paternally expressed 3	Mus musculus	195-201
28654284-3	2017	This structure is designed to mitigate the rapid decomposition of the radical via intramolecular 1,5-hydrogen atom transfer (1,5-HAT) that was observed in its constitutional isomer 1-H with four mPEG-3 groups in the vicinity of the nitrogen-centered radical (1- and 8-positions of TTBC).	ttbc	281-285	paternally expressed 3	Mus musculus	195-201
27461468-5	2016	Under the assumption that, if a gene mediates EGCG"s cancer inhibition, its expression level change caused by EGCG should be opposite to what occurred in the carcinogenesis, we identified Myb and Peg3 as the primary putative genes involved in the cancer inhibitory activity.	epigallocatechin gallate	46-50	paternally expressed 3	Mus musculus	196-200
27461468-5	2016	Under the assumption that, if a gene mediates EGCG"s cancer inhibition, its expression level change caused by EGCG should be opposite to what occurred in the carcinogenesis, we identified Myb and Peg3 as the primary putative genes involved in the cancer inhibitory activity.	epigallocatechin gallate	110-114	paternally expressed 3	Mus musculus	196-200
27461468-7	2016	CONCLUSIONS: Although the actions of EGCG involve multiple targets/pathways, further analysis by mining the existing genomic datasets revealed that the upregulations of Myb and Peg3 are likely the key anti-cancer events of EGCG in vivo.	epigallocatechin gallate	37-41	paternally expressed 3	Mus musculus	177-181
27461468-7	2016	CONCLUSIONS: Although the actions of EGCG involve multiple targets/pathways, further analysis by mining the existing genomic datasets revealed that the upregulations of Myb and Peg3 are likely the key anti-cancer events of EGCG in vivo.	epigallocatechin gallate	223-227	paternally expressed 3	Mus musculus	177-181
26633825-3	2015	Therefore, the effect of fluorine on methylation of H19 and Peg3 during early mouse embryos was studied.	Fluorine	25-33	paternally expressed 3	Mus musculus	60-64
26262775-7	2015	EtOH affected methylation of Peg3 (CpG 3, 7 and 9) in paternal spermatozoa and in the cerebral cortices of deaf mice, but the level of mRNA expression did not change, suggesting that other gene regulation may be involved in these processes.	Ethanol	0-4	paternally expressed 3	Mus musculus	29-33
25898838-7	2015	Our results demonstrate that TBTCl treatment results in decreased mRNA levels of imprinted genes H19, Igf2r, and Peg3 during oocyte growth.	tributyltin	29-34	paternally expressed 3	Mus musculus	113-117
26633825-4	2015	It was shown that the H19 gene was significantly downmethylated in E2.5, E3.5, and E4.5 embryos from pregnant mice treated with 120 mg/l NaF in drinking water for 48 h. But methylation of both H19 and Peg3 genes was disrupted when the parent male mice were treated with NaF for 35 days.	Sodium Fluoride	137-140	paternally expressed 3	Mus musculus	201-205
26633825-6	2015	However, when pregnant mice, mated with NaF-treated male mice, were again treated with NaF for 48 h, either H19 or Peg3 methylation in the embryos decreased significantly.	Sodium Fluoride	40-43	paternally expressed 3	Mus musculus	115-119
26633825-6	2015	However, when pregnant mice, mated with NaF-treated male mice, were again treated with NaF for 48 h, either H19 or Peg3 methylation in the embryos decreased significantly.	Sodium Fluoride	87-90	paternally expressed 3	Mus musculus	115-119
26633825-9	2015	Conclusively, we demonstrated that fluorine may adversely affect early embryonic development by disrupting the methylation of H19 and Peg3 through downregulation of DNMT1.	Fluorine	35-43	paternally expressed 3	Mus musculus	134-138
24030355-0	2014	Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo.	Sodium Fluoride	0-15	paternally expressed 3	Mus musculus	52-56
25143347-8	2014	Examination of airway epithelial tissue in an Ussing chamber showed that apical activation of PAR2 by 2at-LIGRLO(PEG3-Pam)-NH2 resulted in a transient decrease in transepithelial resistance that was due to increased apical ion efflux.	2at-ligrlo	102-112	paternally expressed 3	Mus musculus	113-117
25477793-8	2014	In addition, reduced expression of Pten and Peg3 - two genes implicated in autism-like deficits - was observed in the brain of GLA-exposed pups at postnatal day 15.	phosphinothricin	127-130	paternally expressed 3	Mus musculus	44-48
24486713-8	2014	In the circling mice, the highest ethanol exposure increase in methylation (CpG 1, 2, 7 and 11) and decreases in mRNA of Peg3.Thus, chronic paternal ethanol exposure can affect the methylation of imprinted genes in sire sperm that may be passed on to offspring, giving rise to mental deficits.	Ethanol	34-41	paternally expressed 3	Mus musculus	121-125
24486713-8	2014	In the circling mice, the highest ethanol exposure increase in methylation (CpG 1, 2, 7 and 11) and decreases in mRNA of Peg3.Thus, chronic paternal ethanol exposure can affect the methylation of imprinted genes in sire sperm that may be passed on to offspring, giving rise to mental deficits.	Ethanol	149-156	paternally expressed 3	Mus musculus	121-125
24390239-5	2014	The data revealed DEHP exposure significantly reduced the percentage of methylated CpG sites in Igf2r and Peg3 differentially methylated regions (DMRs) in primordial germ cells from female and male fetal mouse, particularly, in the oocytes of 21 dpp mice (F1), which were produced by the pregnant micetreated with DEHP.	dipalmitoylphosphatidylserine	246-249	paternally expressed 3	Mus musculus	106-110
24030355-4	2014	Data indicate that H19, a paternally imprinted gene, compared to control embryos, was less methylated in 8-cell embryos from pregnant mice treated with NaF (100 mg/l) in drinking water for 48 h. Peg3, a maternally imprinted gene, and the Line1 repeated sequence were similarly methylated in NaF-treated and control embryos.	Sodium Fluoride	152-155	paternally expressed 3	Mus musculus	195-199
24030355-4	2014	Data indicate that H19, a paternally imprinted gene, compared to control embryos, was less methylated in 8-cell embryos from pregnant mice treated with NaF (100 mg/l) in drinking water for 48 h. Peg3, a maternally imprinted gene, and the Line1 repeated sequence were similarly methylated in NaF-treated and control embryos.	Water	179-184	paternally expressed 3	Mus musculus	195-199
24030355-4	2014	Data indicate that H19, a paternally imprinted gene, compared to control embryos, was less methylated in 8-cell embryos from pregnant mice treated with NaF (100 mg/l) in drinking water for 48 h. Peg3, a maternally imprinted gene, and the Line1 repeated sequence were similarly methylated in NaF-treated and control embryos.	Sodium Fluoride	291-294	paternally expressed 3	Mus musculus	195-199
24030355-7	2014	Female mice mated with NaF-treated male mice (35 days) had less methylated H19, but Peg3 was significantly more methylated.	Sodium Fluoride	23-26	paternally expressed 3	Mus musculus	84-88
23999071-8	2013	Reoxygenation with 100% oxygen after hypoxia uniquely upregulated Gadd45g, Dusp1, Peg3, and Tgm2.	Oxygen	2-8	paternally expressed 3	Mus musculus	82-86
24150277-5	2014	The resulting azido-sugar antibody was conjugated to phosphine-polyethylene glycol (PEG3)-biotin via a modified Staudinger reaction.	azido-sugar	14-25	paternally expressed 3	Mus musculus	84-88
23683595-2	2013	The prosthetic groups were conjugated to azide- and PEG3-modified bombesin(6-14) analogues via copper-catalyzed azide-alkyne cycloaddition couplings to yield mono- and di-mini-PEGylated ligands for PET imaging of the gastrin- releasing peptide receptor.	Copper	95-101	paternally expressed 3	Mus musculus	52-56
23683595-2	2013	The prosthetic groups were conjugated to azide- and PEG3-modified bombesin(6-14) analogues via copper-catalyzed azide-alkyne cycloaddition couplings to yield mono- and di-mini-PEGylated ligands for PET imaging of the gastrin- releasing peptide receptor.	Azides	112-117	paternally expressed 3	Mus musculus	52-56
23683595-2	2013	The prosthetic groups were conjugated to azide- and PEG3-modified bombesin(6-14) analogues via copper-catalyzed azide-alkyne cycloaddition couplings to yield mono- and di-mini-PEGylated ligands for PET imaging of the gastrin- releasing peptide receptor.	Alkynes	118-124	paternally expressed 3	Mus musculus	52-56
23515675-5	2013	In superovulated oocytes of diabetic mice, the methylation pattern of Peg3 differential methylation regions (DMR) was affected in a time-dependent manner, and evident demethylation was observed on Day 35 after STZ injection.	Streptozocin	210-213	paternally expressed 3	Mus musculus	70-74
23142538-7	2013	These results show that the robust effects of TCDD on the mRNA expression of Snrpn, Peg3 and Igf2r genes in the sperm and of Igf2r in the muscle and liver are unrelated to changes in methylation in their respective genes.	Polychlorinated Dibenzodioxins	46-50	paternally expressed 3	Mus musculus	84-88
22699882-5	2012	DNA methylation of imprinting genes, Igf2r, Peg3 and H19, was decreased with the increase of BPA concentration in fetal mouse germ cells (p < 0.01).The relative mRNA levels of Nobox were lower in BPA-treated group compared to control (BPA free) in female fetal germ cells, but in male fetal germ cells, a significant higher in Nobox expression was observed in BPA-treated group compared to control.	bisphenol A	93-96	paternally expressed 3	Mus musculus	44-48
22394678-5	2012	However, the allele-specific DNA methylation patterns of the DMRs of Peg3, Zim2 and Zim3 were not affected in the mice that inherited the KO allele either paternally or maternally.	dmrs	61-65	paternally expressed 3	Mus musculus	69-73
21151140-4	2011	Here we show that the progression elevated gene-3 (PEG-3) promoter, derived from a rodent gene mediating tumor progression and metastatic phenotypes, can be used to drive imaging reporters selectively to enable detection of micrometastatic disease in mouse models of human melanoma and breast cancer using bioluminescence and radionuclide-based molecular imaging techniques.	Radioisotopes	326-338	paternally expressed 3	Mus musculus	22-56
22131059-4	2012	Our results demonstrated that BPA exposure resulted in hypomethylation of imprinted gene Igf2r and Peg3 during oocyte growth, and enhanced estrogen receptor (ER) expression at the levels of mRNA and protein.	bisphenol A	30-33	paternally expressed 3	Mus musculus	99-103
21382472-3	2011	We evaluated the possible effects of alcohol administration in pregnant mice on the methylation pattern of 5 imprinted genes (H19, Gtl2, Peg1, Snrpn and Peg3) in somatic and sperm cell DNAs of the male offspring.	Alcohols	37-44	paternally expressed 3	Mus musculus	153-157
15866342-2	2005	Attachment of two or three mPEG chains to CPA resulted in the generation of mPEG2-CPA and mPEG3-CPA analogs with significantly enhanced plasma half-lives, especially during the distribution phase.	monomethoxypolyethylene glycol	27-31	paternally expressed 3	Mus musculus	90-95
19628663-7	2009	Overall, the current study suggests that YY1 likely plays a role in the de novo DNA methylation of the DMRs of Peg3 and Xist during oogenesis and also in the maintenance of unmethylation status of these DMRs during spermatogenesis.	dmrs	103-107	paternally expressed 3	Mus musculus	111-115
16145677-6	2005	Bisulfite sequencing revealed that reactivation of maternal alleles of Peg3 and Snrpn in specific tissues was accompanied by partial demethylation at their potential imprinting control regions.	hydrogen sulfite	0-9	paternally expressed 3	Mus musculus	71-75