PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
21880854-10	2011	The ratio of IL-10 to IFNG was increased by dexamethasone on day 9.	Dexamethasone	44-57	interleukin 10	Equus caballus	13-18
17671392-11	2007	There was an increased level of IL-10 in supernatants from PBMC of healthy horses born in mainland Europe and stimulated polyclonally or with IBH allergen.	ibh	142-145	interleukin 10	Equus caballus	32-37
19766323-2	2010	In this study, we determined the effects of an adenosine A(2A) receptor agonist, ATL313, on the expression of mRNAs for four pro-inflammatory mediators, IL-1beta, IL-8, COX-2, and TNF-alpha, and the mRNA and protein for the anti-inflammatory cytokine, IL-10 in equine monocytes incubated with lipopolysaccharide (LPS).	ATL 313	81-87	interleukin 10	Equus caballus	252-257
18061278-9	2008	All three anti-IL-10 mAbs detected a positive population in PMA stimulated lymphocytes which was absent in the medium controls.	Tetradecanoylphorbol Acetate	60-63	interleukin 10	Equus caballus	15-20
18061278-12	2008	Double staining with IL-4 or interferon-gamma (IFN-gamma) indicated that PMA and ionomycin stimulation induced 80% IL-10(+)/IFN-gamma(+) lymphocytes, while only 5% IL-10(+)/IL-4(+) cells were observed.	Tetradecanoylphorbol Acetate	73-76	interleukin 10	Equus caballus	115-120
18061278-12	2008	Double staining with IL-4 or interferon-gamma (IFN-gamma) indicated that PMA and ionomycin stimulation induced 80% IL-10(+)/IFN-gamma(+) lymphocytes, while only 5% IL-10(+)/IL-4(+) cells were observed.	Tetradecanoylphorbol Acetate	73-76	interleukin 10	Equus caballus	164-169
18061278-12	2008	Double staining with IL-4 or interferon-gamma (IFN-gamma) indicated that PMA and ionomycin stimulation induced 80% IL-10(+)/IFN-gamma(+) lymphocytes, while only 5% IL-10(+)/IL-4(+) cells were observed.	Ionomycin	81-90	interleukin 10	Equus caballus	115-120
18061278-12	2008	Double staining with IL-4 or interferon-gamma (IFN-gamma) indicated that PMA and ionomycin stimulation induced 80% IL-10(+)/IFN-gamma(+) lymphocytes, while only 5% IL-10(+)/IL-4(+) cells were observed.	Ionomycin	81-90	interleukin 10	Equus caballus	164-169
21168921-12	2011	IL-10 levels were lower in lesional compared to non-lesional skin (p=0.06) and also lower (p=0.06) in the blood of IBH-affected than of healthy horses.	ibh	115-118	interleukin 10	Equus caballus	0-5
18082270-11	2008	It is suggested that in this naturally occurring IgE-mediated allergy, IL-10 and TGF-beta1 have a role in the down-regulation of IL-4-induced allergen-specific Th2 cells, thereby reducing the incidence of IBH.	ibh	205-208	interleukin 10	Equus caballus	71-76
17671392-12	2007	CONCLUSIONS: Modulation of IBH incidence is governed by altered Th1/Th2 ratio, which might be influenced by IL-10.	ibh	27-30	interleukin 10	Equus caballus	108-113
24438346-8	2014	In contrast, inhibition of PGE2 restored T cell proliferation, restored the secretion of tumor necrosis factor-alpha and interferon-gamma, and increased IL-10 levels.	Dinoprostone	27-31	interleukin 10	Equus caballus	153-158
35286327-12	2022	Alveolar macrophages incubated with SALSA plus LPS released significantly less CXC motif chemokine ligand 1, interleukin-8, interleukin-10, and tumor necrosis factor alpha, and more granulocyte colony stimulating factor (G-CSF), compared to macrophages incubated with LPS alone.	methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate	36-41	interleukin 10	Equus caballus	124-138
32671108-10	2020	Treatment with ACS and APS caused a trend in upregulation of IL-10 expression in synovium and type II collagen and aggrecan expression in cartilage.	aps	23-26	interleukin 10	Equus caballus	61-66
30929785-8	2019	There was a dose-dependent increase in plasma DHA, and highest arachidonic acid was found in 20 and 50 g. Vitamin E was lowest in 20 and 50 g. LT did not change IL-6, downregulated IL-1 and TNF-alpha, upregulated IL-10, and interferon gamma.	Vitamin E	106-115	interleukin 10	Equus caballus	213-218
25174977-5	2014	Colostral T-cells (n=13) responded to stimulation with PMA/ionomycin with a significantly higher magnitude of IL-17 (p=0.037) and similar IFN-gamma concentrations (p=0.305), while IL-4 (p=0.0002) and IL-10 (p=0.0002) production was decreased compared to PBMC.	Tetradecanoylphorbol Acetate	55-58	interleukin 10	Equus caballus	200-205
17139543-0	2006	Clenbuterol affects the expression of messenger RNA for interleukin 10 in peripheral leukocytes from horses challenged intrabronchially with lipopolysaccharides.	Clenbuterol	0-11	interleukin 10	Equus caballus	56-70
17139543-5	2006	However in those horses that were treated with clenbuterol the LPS-induced IL-10 mRNA expression was shown to be suppressed.	Clenbuterol	47-58	interleukin 10	Equus caballus	75-80
17139543-7	2006	Thus the results of this study indicated that clenbuterol can modulate the expression of IL-10 mRNA in peripheral white blood cells in those horses with small airway diseases that have been exposed to LPS.	Clenbuterol	46-57	interleukin 10	Equus caballus	89-94
31190704-7	2019	Results: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis displayed a molecular weight of 15 kDa for IL-4 and 19 kDa for IL-10.	Sodium Dodecyl Sulfate	9-31	interleukin 10	Equus caballus	139-144
31190704-7	2019	Results: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis displayed a molecular weight of 15 kDa for IL-4 and 19 kDa for IL-10.	polyacrylamide	32-46	interleukin 10	Equus caballus	139-144
29813093-1	2018	OBJECTIVE: The aim of this study was to verify whether transient inflammatory reactions induced by intra-articular medicinal ozone administration affect joint components, by in vivo evaluation of inflammatory (prostaglandin E2, Substance P, Interleukin-6, Interleukine-1, Tumor Necrosis Factor), anti-inflammatory (Interleukin-10) and oxidative (superoxide dismutase activity and oxidative burst) biomarkers and extracellular matrix degradation products (chondroitin sulphate and hyaluronic acid) in synovial fluid.	Ozone	125-130	interleukin 10	Equus caballus	315-329
23889243-8	2013	The decreased suppression in IBH-affected horses was associated with a significantly higher proportion of IL-4(+) cells and a lower percentage of FoxP3(+) IL-10(+) compared to controls.	ibh	29-32	interleukin 10	Equus caballus	155-160
23820116-5	2013	In contrast, horses administered CHO developed clinical signs consistent with systemic inflammation, had more delayed increases in TNF-alpha, IL-10 and total leukocyte counts, and had marked increases in laminar tissue expression of the genes associated with inflammation.	CAV protocol	33-36	interleukin 10	Equus caballus	142-147
23658361-16	2013	Whole blood mRNA expression of IL-10 was greater for SS compared with LS, AS, and SP (P = 0.043).	TFF2 protein, human	82-84	interleukin 10	Equus caballus	31-36
23447881-5	2012	RESULTS: Equine colostral carbohydrates significantly reduced LPS-induced TNF-alpha protein at both times measured and significantly reduced LPS-induced TNF-alpha, IL-6 and IL-10 mRNA expression by PBMCs.	Carbohydrates	26-39	interleukin 10	Equus caballus	173-178
21700344-2	2012	We have shown previously that peripheral blood mononuclear cells (PBMC) from IBH-affected horses produce higher levels of IL-4 and lower levels of IL-10 and TGF-beta1 than those from healthy horses, suggesting that IBH is associated with a reduced regulatory immune response.	ibh	77-80	interleukin 10	Equus caballus	147-152