PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
28153445-5	2017	Further we demonstrate that its 5"-monophosphate, the dominant cancer cell metabolite, inhibits the candidate oncogene DNPH1.	5"-monophosphate	32-48	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	119-124
25108359-0	2014	6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.	6-(hetero)arylpurine nucleotides	0-32	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	71-76
25108359-2	2014	Here, we describe the synthesis of a series of novel 6-aryl- and 6-heteroarylpurine riboside 5"-monophosphates via Suzuki-Miyaura cross-coupling reactions, and their ability to inhibit recombinant rat and human DNPH1.	6-aryl- and 6-heteroarylpurine riboside 5"-monophosphates	53-110	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	211-216
24260472-0	2013	N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1.	n (6)-substituted amps	0-22	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	69-74
24260472-1	2013	The gene dnph1 (or rcl) encodes a hydrolase that cleaves the 2"-deoxyribonucleoside 5"-monophosphate (dNMP) N-glycosidic bond to yield a free nucleobase and 2-deoxyribose 5-phosphate.	2"-deoxyribonucleoside 5"-monophosphate	61-100	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-14
24260472-1	2013	The gene dnph1 (or rcl) encodes a hydrolase that cleaves the 2"-deoxyribonucleoside 5"-monophosphate (dNMP) N-glycosidic bond to yield a free nucleobase and 2-deoxyribose 5-phosphate.	dnmp	102-106	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-14
24260472-1	2013	The gene dnph1 (or rcl) encodes a hydrolase that cleaves the 2"-deoxyribonucleoside 5"-monophosphate (dNMP) N-glycosidic bond to yield a free nucleobase and 2-deoxyribose 5-phosphate.	2-deoxyribose 5-phosphate	157-182	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-14
24260472-3	2013	From this result, we asked whether N (6)-substituted AMPs, and among them, cytotoxic cytokinin riboside 5"-monophosphates, may inhibit DNPH1.	n (6)	35-40	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	135-140
24260472-3	2013	From this result, we asked whether N (6)-substituted AMPs, and among them, cytotoxic cytokinin riboside 5"-monophosphates, may inhibit DNPH1.	adenosine 5'-phosphorothioate	53-57	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	135-140
24260472-3	2013	From this result, we asked whether N (6)-substituted AMPs, and among them, cytotoxic cytokinin riboside 5"-monophosphates, may inhibit DNPH1.	riboside 5"-monophosphates	95-121	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	135-140
19720067-1	2009	RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2"-deoxyribonucleoside 5"-monophosphates, a novel enzymatic reaction reported only recently.	purine	66-72	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	0-3
23385460-1	2013	Rcl is a novel N-glycoside hydrolase found in mammals that shows specificity for the hydrolysis of 5"-monophosphate nucleotides.	5"-monophosphate nucleotides	99-127	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	0-3
19720067-1	2009	RCL is an enzyme that catalyzes the N-glycosidic bond cleavage of purine 2"-deoxyribonucleoside 5"-monophosphates, a novel enzymatic reaction reported only recently.	2"-deoxyribonucleoside 5"-monophosphates	73-113	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	0-3
19822152-1	2009	The gene Rcl encodes a deoxynucleoside 5"-monophosphate N-glycosidase that catalyzes the hydrolysis of the N-glycosidic bond of the nucleotide to give deoxyribose 5-phosphate and a nucleobase, preferentially a purine.	deoxyribose 5-phosphate	151-174	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-12
11671509-4	1997	A new, convenient synthesis of symmetrical tertiary imines from tert-RCl, tert-RCN, and Na is described.	Imines	52-58	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	69-72
19822152-1	2009	The gene Rcl encodes a deoxynucleoside 5"-monophosphate N-glycosidase that catalyzes the hydrolysis of the N-glycosidic bond of the nucleotide to give deoxyribose 5-phosphate and a nucleobase, preferentially a purine.	nucleobase	181-191	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-12
19822152-1	2009	The gene Rcl encodes a deoxynucleoside 5"-monophosphate N-glycosidase that catalyzes the hydrolysis of the N-glycosidic bond of the nucleotide to give deoxyribose 5-phosphate and a nucleobase, preferentially a purine.	purine	210-216	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	9-12
14687577-7	2004	Disulfide bonds can be formed in double-cysteine mutants with substitutions at positions P11 or P13 of the RCL and neighboring residues in beta-sheet A.	Disulfides	0-9	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	107-110
14687577-7	2004	Disulfide bonds can be formed in double-cysteine mutants with substitutions at positions P11 or P13 of the RCL and neighboring residues in beta-sheet A.	Cysteine	40-48	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	107-110
29273295-6	2018	E. muelleri DNPH1 is inhibited by the purine nucleotides with different numbers of 5"-phosphate groups (n = 1-4).	purine	38-44	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	12-17
34131188-6	2021	However, the steel with large amount of carbide generation (carburized for 30 min) tends to have higher corrosion resistance (indicated by higher values of Rcl and Rct) than the smaller ones (10 and 20 min) due to the effect of phase, grain size, morphology, and amount of compound formation.	carbide	40-47	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	156-159
33833118-3	2021	We show that inhibition of DNPH1, a protein that eliminates cytotoxic nucleotide 5-hydroxymethyl-deoxyuridine (hmdU) monophosphate, potentiates the sensitivity of BRCA-deficient cells to PARP inhibitors (PARPi).	nucleotide 5-hydroxymethyl-deoxyuridine (hmdu) monophosphate	70-130	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	27-32
33998087-10	2021	Among illegal opioids, including heroin, oxycodone and hydrocodone, street prices increased and law enforcement seizures decreased in RCL states.	Heroin	33-39	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	134-137
33998087-10	2021	Among illegal opioids, including heroin, oxycodone and hydrocodone, street prices increased and law enforcement seizures decreased in RCL states.	Oxycodone	41-50	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	134-137
33998087-10	2021	Among illegal opioids, including heroin, oxycodone and hydrocodone, street prices increased and law enforcement seizures decreased in RCL states.	Hydrocodone	55-66	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	134-137
29273295-6	2018	E. muelleri DNPH1 is inhibited by the purine nucleotides with different numbers of 5"-phosphate groups (n = 1-4).	Phosphates	86-95	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	12-17
29273295-8	2018	Hence, the functioning of DNPH1 in cells where the natural ATP and GTP concentrations are much higher than those of the substrates, dNMPs, should normally be downregulated.	Adenosine Triphosphate	59-62	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	26-31
29273295-8	2018	Hence, the functioning of DNPH1 in cells where the natural ATP and GTP concentrations are much higher than those of the substrates, dNMPs, should normally be downregulated.	Guanosine Triphosphate	67-70	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	26-31
29273295-8	2018	Hence, the functioning of DNPH1 in cells where the natural ATP and GTP concentrations are much higher than those of the substrates, dNMPs, should normally be downregulated.	dnmps	132-137	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	26-31
29273295-9	2018	We demonstrate for the first time the existence of biologically relevant natural inhibitors of DNPH1, namely ATP and GTP.	Adenosine Triphosphate	109-112	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	95-100
29273295-9	2018	We demonstrate for the first time the existence of biologically relevant natural inhibitors of DNPH1, namely ATP and GTP.	Guanosine Triphosphate	117-120	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	Homo sapiens	95-100