PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 34630087-0 2021 USP47-Mediated Deubiquitination and Stabilization of TCEA3 Attenuates Pyroptosis and Apoptosis of Colorectal Cancer Cells Induced by Chemotherapeutic Doxorubicin. Doxorubicin 150-161 ubiquitin specific peptidase 47 Homo sapiens 0-5 34030041-0 2021 USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide. parthenolide 76-88 ubiquitin specific peptidase 47 Homo sapiens 0-5 34030041-7 2021 Furthermore, we identified Parthenolide (PTL), a natural sesquiterpene lactone, as a novel USP47 inhibitor. parthenolide 27-39 ubiquitin specific peptidase 47 Homo sapiens 91-96 34030041-7 2021 Furthermore, we identified Parthenolide (PTL), a natural sesquiterpene lactone, as a novel USP47 inhibitor. parthenolide 41-44 ubiquitin specific peptidase 47 Homo sapiens 91-96 34030041-7 2021 Furthermore, we identified Parthenolide (PTL), a natural sesquiterpene lactone, as a novel USP47 inhibitor. sesquiterpene lactone 57-78 ubiquitin specific peptidase 47 Homo sapiens 91-96 33576460-0 2021 Long non-coding RNA KCNQ1OT1 promotes nasopharyngeal carcinoma cell cisplatin resistance via the miR-454/USP47 axis. Cisplatin 68-77 ubiquitin specific peptidase 47 Homo sapiens 105-110 29786670-9 2018 We found that USP47 contributes to cell viability and chemoresistance in NCI-N87 gastric carcinoma cells treated with etoposide and camptothecin. Etoposide 118-127 ubiquitin specific peptidase 47 Homo sapiens 14-19 29786670-9 2018 We found that USP47 contributes to cell viability and chemoresistance in NCI-N87 gastric carcinoma cells treated with etoposide and camptothecin. Camptothecin 132-144 ubiquitin specific peptidase 47 Homo sapiens 14-19 32379981-10 2020 Rescue assays suggested that DSCAM-AS1 regulated OS progression through binding with miR-101-3p to modulate USP47 expression. -101-3p 88-95 ubiquitin specific peptidase 47 Homo sapiens 108-113 26115687-4 2015 USP47 released Ub from Ub-aminoacyl-4-metheylcoumaryl-7-amide and Ub-tagged granzyme B. aminoacyl-4-metheylcoumaryl-7-amide 26-61 ubiquitin specific peptidase 47 Homo sapiens 0-5 26115687-5 2015 The substitution of the potential nucleophile Cys109 with Ser severely abrogated the Ub-releasing activity of USP47, indicating that USP47 is indeed a cysteine DUB. Cysteine 151-159 ubiquitin specific peptidase 47 Homo sapiens 110-115 26115687-5 2015 The substitution of the potential nucleophile Cys109 with Ser severely abrogated the Ub-releasing activity of USP47, indicating that USP47 is indeed a cysteine DUB. Cysteine 151-159 ubiquitin specific peptidase 47 Homo sapiens 133-138 26115687-8 2015 Of the inhibitors tested, N-ethylmaleimide, Zn ion and Ub aldehyde revealed a dose-dependent inhibition of USP47. Ethylmaleimide 26-42 ubiquitin specific peptidase 47 Homo sapiens 107-112 26115687-8 2015 Of the inhibitors tested, N-ethylmaleimide, Zn ion and Ub aldehyde revealed a dose-dependent inhibition of USP47. Zinc 44-46 ubiquitin specific peptidase 47 Homo sapiens 107-112 25429829-7 2015 Our results uncovered that miR-204-5p acts as a tumor suppressor in GC through inhibiting USP47 and RAB22A. mir-204-5p 27-37 ubiquitin specific peptidase 47 Homo sapiens 90-95 34630087-5 2021 In cultured CRC cells, knockdown of USP47 increased pyroptosis and apoptosis induced by chemotherapeutic doxorubicin. Doxorubicin 105-116 ubiquitin specific peptidase 47 Homo sapiens 36-41 34630087-7 2021 While ectopic expression of USP47 increased cellular TCEA3 and resistance to doxorubicin, the effect was markedly attenuated by TCEA3 knockdown. Doxorubicin 77-88 ubiquitin specific peptidase 47 Homo sapiens 28-33 35205710-0 2022 MicroRNA-101-3p Suppresses Cancer Cell Growth by Inhibiting the USP47-Induced Deubiquitination of RPL11. microrna-101-3p 0-15 ubiquitin specific peptidase 47 Homo sapiens 64-69 35205710-2 2022 Here, we demonstrate that miR-101-3p regulates the RPL11-MDM2-p53 pathway by targeting ubiquitin-specific peptidase 47 (USP47), consequently inhibiting cancer cell proliferation. mir-101-3p 26-36 ubiquitin specific peptidase 47 Homo sapiens 87-118 35205710-2 2022 Here, we demonstrate that miR-101-3p regulates the RPL11-MDM2-p53 pathway by targeting ubiquitin-specific peptidase 47 (USP47), consequently inhibiting cancer cell proliferation. mir-101-3p 26-36 ubiquitin specific peptidase 47 Homo sapiens 120-125 35205710-3 2022 We confirm that miR-101-3p directly binds to the 3"-UTR region of the USP47 gene and inhibits USP47 expression. mir-101-3p 16-26 ubiquitin specific peptidase 47 Homo sapiens 70-75 35205710-3 2022 We confirm that miR-101-3p directly binds to the 3"-UTR region of the USP47 gene and inhibits USP47 expression. mir-101-3p 16-26 ubiquitin specific peptidase 47 Homo sapiens 94-99 35205710-7 2022 Indeed, miR-101-3p regulates RPL11 localization and its interaction with MDM2 by inhibiting the USP47-induced deubiquitination of RPL11. mir-101-3p 8-18 ubiquitin specific peptidase 47 Homo sapiens 96-101 35205710-9 2022 Together, our findings suggest that miR-101-3p functions as a tumor suppressor by targeting USP47 and could be a potential therapeutic target for cancers. mir-101-3p 36-46 ubiquitin specific peptidase 47 Homo sapiens 92-97 35141006-6 2022 Mechanistic investigations showed that USP47 promoted NSCLC development, which depends a lot on directly binding to and deubiquitination of the basic leucine zipper transcription factor 1 (BACH1, BTB and CNC homology 1). Leucine 150-157 ubiquitin specific peptidase 47 Homo sapiens 39-44