PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 3129188-8 1988 Therefore, it was concluded that this guanine nucleotide-binding protein isolated from neuroblastoma was very similar, if not identical, to brain G(o) alpha. Guanine Nucleotides 38-56 tripartite motif containing 47 Homo sapiens 146-156 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Nitrogen 0-1 tripartite motif containing 47 Homo sapiens 42-45 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Nitrogen 0-1 tripartite motif containing 47 Homo sapiens 84-87 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Nitrogen 0-1 tripartite motif containing 47 Homo sapiens 84-87 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Nitrogen 0-1 tripartite motif containing 47 Homo sapiens 84-87 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Nitrogen 36-37 tripartite motif containing 47 Homo sapiens 42-45 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. myr 38-41 tripartite motif containing 47 Homo sapiens 42-45 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Glycine 80-83 tripartite motif containing 47 Homo sapiens 84-87 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Glycine 80-83 tripartite motif containing 47 Homo sapiens 84-87 2692561-2 1989 N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication. Glycine 80-83 tripartite motif containing 47 Homo sapiens 84-87 3263365-5 1988 Of the N-Myr-compounds tested, N-Myr-GOA remarkably prevented the myristoylation of p19gag and p17gag, but N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA did not. N-myristoylglycine 107-116 tripartite motif containing 47 Homo sapiens 37-40 3263365-5 1988 Of the N-Myr-compounds tested, N-Myr-GOA remarkably prevented the myristoylation of p19gag and p17gag, but N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA did not. n-myr-gly-gly 107-120 tripartite motif containing 47 Homo sapiens 121-124 3263365-5 1988 Of the N-Myr-compounds tested, N-Myr-GOA remarkably prevented the myristoylation of p19gag and p17gag, but N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA did not. n-myr-gly-gly 107-120 tripartite motif containing 47 Homo sapiens 121-124 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Sodium Chloride 6-10 tripartite motif containing 47 Homo sapiens 80-88 3152020-0 1988 Signal transduction by guanine nucleotide-binding proteins: possible molecular basis for multiple forms of Go alpha mRNA. Guanine Nucleotides 23-41 tripartite motif containing 47 Homo sapiens 107-115 2822234-2 1987 GO alpha in the neuroendocrine tumors was present both in the soluble fraction, and cholate-extractable membrane-bound fraction of tissues. Cholates 84-91 tripartite motif containing 47 Homo sapiens 0-8 3102490-7 1987 Salts of both chloride and bromide increased the affinity of Go alpha for GTP gamma S; fluoride and iodide were essentially ineffective. Chlorides 14-22 tripartite motif containing 47 Homo sapiens 61-69 3102490-7 1987 Salts of both chloride and bromide increased the affinity of Go alpha for GTP gamma S; fluoride and iodide were essentially ineffective. Bromides 27-34 tripartite motif containing 47 Homo sapiens 61-69 3102490-7 1987 Salts of both chloride and bromide increased the affinity of Go alpha for GTP gamma S; fluoride and iodide were essentially ineffective. Fluorides 87-95 tripartite motif containing 47 Homo sapiens 61-69 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Tryptophan 53-63 tripartite motif containing 47 Homo sapiens 80-88 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Guanosine 5'-O-(3-Thiotriphosphate) 100-135 tripartite motif containing 47 Homo sapiens 80-88 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Guanosine Triphosphate 137-140 tripartite motif containing 47 Homo sapiens 80-88 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Sulfur 147-148 tripartite motif containing 47 Homo sapiens 80-88 3102490-2 1987 Thus, NaCl stimulated the intensity of the intrinsic tryptophan fluorescence of Go alpha with bound guanosine 5"-(3-O-thio)triphosphate (GTP gamma S) and GTP, but not GDP. Guanosine Triphosphate 154-157 tripartite motif containing 47 Homo sapiens 80-88 213641-0 1978 Alcian blue staining intestinal goblet cell antigen (GOA): a marker for gastric signet ring cell and colonic colloidal carcinoma. Alcian Blue 0-11 tripartite motif containing 47 Homo sapiens 53-56 213641-1 1978 An Alcian blue staining, perchloric acid-soluble, antigenic acidic mucosubstance (GOA) was purified from human gastric signet ring cell carcinoma with DEAE-cellulose chromatography, Seqhadex G-200 and preparative polycrylamide gel electrophoresis. Alcian Blue 3-14 tripartite motif containing 47 Homo sapiens 25-86 213641-1 1978 An Alcian blue staining, perchloric acid-soluble, antigenic acidic mucosubstance (GOA) was purified from human gastric signet ring cell carcinoma with DEAE-cellulose chromatography, Seqhadex G-200 and preparative polycrylamide gel electrophoresis. 2-diethylaminoethanol 151-155 tripartite motif containing 47 Homo sapiens 25-86 213641-1 1978 An Alcian blue staining, perchloric acid-soluble, antigenic acidic mucosubstance (GOA) was purified from human gastric signet ring cell carcinoma with DEAE-cellulose chromatography, Seqhadex G-200 and preparative polycrylamide gel electrophoresis. seqhadex g-200 182-196 tripartite motif containing 47 Homo sapiens 25-86 213641-1 1978 An Alcian blue staining, perchloric acid-soluble, antigenic acidic mucosubstance (GOA) was purified from human gastric signet ring cell carcinoma with DEAE-cellulose chromatography, Seqhadex G-200 and preparative polycrylamide gel electrophoresis. polycrylamide 213-226 tripartite motif containing 47 Homo sapiens 25-86 1022674-0 1976 Reverse dhumti smoking in Goa: an epidemiologic study of 5449 villagers for oral precancerous lesions. dhumti 8-14 tripartite motif containing 47 Homo sapiens 26-29 32476201-7 2020 DISCUSSION AND CONCLUSIONS: Households in Goa, India with a member with alcohol dependence display patterns consistent with a poverty trap, though the mechanisms derived from these qualitative data need to be further demonstrated by longitudinal quantitative data to corroborate a causal relationship between alcohol use disorders and poverty. Alcohols 72-79 tripartite motif containing 47 Homo sapiens 42-45 4667544-0 1972 [Effectiveness of anti-foot-and-mouth disease GOA-formol vaccine with saponin]. Formaldehyde 50-56 tripartite motif containing 47 Homo sapiens 46-49 4667544-0 1972 [Effectiveness of anti-foot-and-mouth disease GOA-formol vaccine with saponin]. Saponins 70-77 tripartite motif containing 47 Homo sapiens 46-49 33791968-3 2021 Higher bioavailable nitrogen concentrations in the sediments were recorded in Coringa mangroves (36.27 +- 14.7 mug g-1) and Bhitarkanika (18.54 +- 5.9 mug g-1) mangroves in the east coast followed by Karnataka (15.51 +- 8.26 mug g-1), Goa, (10.18 +- 9.96 mug g-1) and Kerala (6.36 +- 5.05 mug g-1) mangroves in the west coast. Nitrogen 20-28 tripartite motif containing 47 Homo sapiens 235-238 32603762-9 2020 Additionally, treatment with LiCl reversed the inhibitory effects of TRIM47 knockdown on cell proliferation and migration in U87 cells. Lithium Chloride 29-33 tripartite motif containing 47 Homo sapiens 69-75 33079007-0 2021 Domiciliary alcohol detoxification outcomes: a study from Goa, India. Alcohols 12-19 tripartite motif containing 47 Homo sapiens 58-61 32476201-7 2020 DISCUSSION AND CONCLUSIONS: Households in Goa, India with a member with alcohol dependence display patterns consistent with a poverty trap, though the mechanisms derived from these qualitative data need to be further demonstrated by longitudinal quantitative data to corroborate a causal relationship between alcohol use disorders and poverty. Alcohols 309-316 tripartite motif containing 47 Homo sapiens 42-45 31093781-1 2019 The rationale of the current study was to establish that mining and associated activities are the chief sources of trace metal contamination in the Zuari estuary, Goa. Metals 121-126 tripartite motif containing 47 Homo sapiens 163-166 32109969-4 2020 Results PGT-A increased the costs per live birth in all scenarios (GKV: + 208%; PKV: + 49%; simple GOA factor: + 89%). pgt-a 8-13 tripartite motif containing 47 Homo sapiens 99-102 32601774-2 2020 The emphasis was to look for spatial and temporal variation in the sedimentation rate along the continental shelf of eastern Arabian Sea between Goa to Kochi for water depth <= 150 m. This study showed varying sedimentation rates in coastal and distant sediment cores. Water 162-167 tripartite motif containing 47 Homo sapiens 145-148 31797274-7 2020 Sulphate dominated the aerosol composition at both Goa (57-64%) and Visakhapatnam (43-55%) followed by NO3- (5-16% and 6-18%, respectively) where the former component was higher in PM10 and PM2.5. Sulfates 0-8 tripartite motif containing 47 Homo sapiens 51-54 31797274-11 2020 Notable relations between Ca2+ and NO3-, particularly in PM10 at Goa, indicated their release from mining related activities. Nitrates 35-39 tripartite motif containing 47 Homo sapiens 65-68 31178138-10 2019 The suppressive effects of Trim47 knockdown on cerebral I/R were verified in human neuron-like cells stimulated by oxygen and glucose deprivation (OGD). Oxygen 115-121 tripartite motif containing 47 Homo sapiens 27-33 31590838-0 2019 Assessing the source of oil deposited in the surface sediment of Mormugao Port, Goa - A case study of MV Qing incident. Oils 24-27 tripartite motif containing 47 Homo sapiens 80-83 28637313-0 2017 Trajectories of Alcohol Use Disorders and Their Differential Impact: A Population-Based Cohort Study in Goa, India. Alcohols 16-23 tripartite motif containing 47 Homo sapiens 104-107 30686385-3 2019 We aimed to assess the effectiveness and cost-effectiveness of THP peer-delivered (THPP) in Goa, India. thp 63-66 tripartite motif containing 47 Homo sapiens 92-95 30686385-3 2019 We aimed to assess the effectiveness and cost-effectiveness of THP peer-delivered (THPP) in Goa, India. flopropione 83-87 tripartite motif containing 47 Homo sapiens 92-95 30979374-9 2019 Moreover, TRIM47 overexpression played a role in CRC chemoresistance in response to 5-FU therapy. Fluorouracil 84-88 tripartite motif containing 47 Homo sapiens 10-16 29187069-5 2019 The equilibrium time for the adsorption of glyphosate when using GO-alpha-gamma-Fe2O3 was 2 hours and the maximum removal was 92% at 15 C, with a maximum adsorption capacity of 46.8 mg g-1. glyphosate 43-53 tripartite motif containing 47 Homo sapiens 65-73 29187069-7 2019 The thermodynamic parameters showed that the adsorption of glyphosate on GO-alpha-gamma-Fe2O3 was spontaneous, exothermic and thermodynamically favorable at temperature of 15-45 C. Thus the adsorbent material GO-alpha-gamma-Fe2O3 proposed in this study is considered a good candidate to be used in the removal of glyphosate from aqueous solutions, presenting high adsorption capacity, low cost and magnetic properties that facilitate the separation of the adsorbent material. glyphosate 59-69 tripartite motif containing 47 Homo sapiens 73-81 29187069-7 2019 The thermodynamic parameters showed that the adsorption of glyphosate on GO-alpha-gamma-Fe2O3 was spontaneous, exothermic and thermodynamically favorable at temperature of 15-45 C. Thus the adsorbent material GO-alpha-gamma-Fe2O3 proposed in this study is considered a good candidate to be used in the removal of glyphosate from aqueous solutions, presenting high adsorption capacity, low cost and magnetic properties that facilitate the separation of the adsorbent material. glyphosate 59-69 tripartite motif containing 47 Homo sapiens 209-217 29187069-7 2019 The thermodynamic parameters showed that the adsorption of glyphosate on GO-alpha-gamma-Fe2O3 was spontaneous, exothermic and thermodynamically favorable at temperature of 15-45 C. Thus the adsorbent material GO-alpha-gamma-Fe2O3 proposed in this study is considered a good candidate to be used in the removal of glyphosate from aqueous solutions, presenting high adsorption capacity, low cost and magnetic properties that facilitate the separation of the adsorbent material. glyphosate 313-323 tripartite motif containing 47 Homo sapiens 73-81 28665261-0 2019 The onset and progression of alcohol use disorders: A qualitative study from Goa, India. Alcohols 29-36 tripartite motif containing 47 Homo sapiens 77-80 29656175-0 2018 Distribution of environmental tritium in rivers, groundwater, mine water and precipitation in Goa, India. Tritium 30-37 tripartite motif containing 47 Homo sapiens 94-97 29656175-5 2018 The tritium distribution in all the samples shows modern precipitation (post-1950) component in surface and sub-surface hydrosphere of Goa. Tritium 4-11 tripartite motif containing 47 Homo sapiens 135-138 28934621-0 2017 Psychometric properties of GHQ-12 in Goa, India. ghq-12 27-33 tripartite motif containing 47 Homo sapiens 37-40 28186994-7 2017 Gene set enrichment analysis (GSEA) revealed that cancer-related process and pathways, including p53-cell cycle and NFkappaB-epithelial mesenchymal transition (EMT) pathway, were significantly correlated with TRIM47 expression. gsea 30-34 tripartite motif containing 47 Homo sapiens 209-215 28784361-8 2017 CONCLUSION: In order to optimize the usefulness and validity of the GHQ-12, a low cut-off point for CMD may be beneficial in Goa, India. ghq-12 68-74 tripartite motif containing 47 Homo sapiens 125-128 26604001-4 2015 METHODS/DESIGN: THPP is evaluated with two randomised controlled trials: a cluster trial in Rawalpindi, Pakistan, and an individually randomised trial in Goa, India. flopropione 16-20 tripartite motif containing 47 Homo sapiens 154-157 27328397-2 2016 Our earlier studies showed that the source oil for the TBs deposited on the Goa coast in August 2010 is the tanker wash, and the source for subsequent TBs deposited on the Gujarat coast during July 2012 and June 2013 and Goa coast in May 2013 is from Bombay High (BH) oil fields. Oils 43-46 tripartite motif containing 47 Homo sapiens 76-79 27328397-2 2016 Our earlier studies showed that the source oil for the TBs deposited on the Goa coast in August 2010 is the tanker wash, and the source for subsequent TBs deposited on the Gujarat coast during July 2012 and June 2013 and Goa coast in May 2013 is from Bombay High (BH) oil fields. Oils 43-46 tripartite motif containing 47 Homo sapiens 221-224 27328397-3 2016 In the present study, the TBs that were deposited during May 2013 and May 2014 on the Goa coast were backtracked through a trajectory model, primarily to simulate their pathways and identify the reason for the occurrence of TBs only in May, and eventually to identify the origin and the source. Terbium 26-29 tripartite motif containing 47 Homo sapiens 86-89 27281157-9 2016 The percentage of individuals with unrepaired CL/P who were older than the respective target ages ranged from 37.0% (95% CI, 30.6%-43.8%) in Goa to 65.8% (95% CI, 60.3%-70.9%) in Bihar (median, 57.9%; interquartile range, 52.6%-63.4%). Phosphorus 49-50 tripartite motif containing 47 Homo sapiens 141-144 27842714-0 2017 Offshore sediments record the history of onshore iron ore mining in Goa State, India. Iron 49-53 tripartite motif containing 47 Homo sapiens 68-71 26271913-1 2015 Iron ore was mined from the banded iron formations of Goa, India, and transported through the Mandovi and Zuari estuaries for six decades until the ban on mining from September 2012. Iron 0-4 tripartite motif containing 47 Homo sapiens 54-57 26363071-7 2015 Using G protein-activation biosensors, we then demonstrated that ghrelin promoted activation of Gq, Gi1, Gi2, Gi3, Goa, Gob, and G13 but not Gs and G12. Ghrelin 65-72 tripartite motif containing 47 Homo sapiens 115-118 26323861-0 2015 A case study on effects of oil spills and tar-ball pollution on beaches of Goa (India). Oils 27-30 tripartite motif containing 47 Homo sapiens 75-78 26323861-1 2015 This paper reports the impact of oil spills and tar-ball pollution on the coastal ecosystem of Goa. Oils 33-36 tripartite motif containing 47 Homo sapiens 95-98 24748360-0 2014 Morbidity among iron ore mine workers in Goa. Iron 16-20 tripartite motif containing 47 Homo sapiens 41-44 26549791-2 2015 OBJECTIVES: We studied different versions of the Alcohol Use Disorders Identification Test (AUDIT) comparing their performance to the full AUDIT and an AUD measure as screeners for alcohol use problems in Goa, India. Alcohols 181-188 tripartite motif containing 47 Homo sapiens 205-208 15618020-0 2005 Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha. Guanosine Diphosphate 25-28 tripartite motif containing 47 Homo sapiens 96-103 24459310-0 2013 The course and outcome of alcohol use disorders in men in Goa: A population- based follow-up study. Alcohols 26-33 tripartite motif containing 47 Homo sapiens 58-61 22892996-0 2013 Bacterial response to dynamic metal concentrations in the surface sediments of a solar saltern (Goa, India). Metals 30-35 tripartite motif containing 47 Homo sapiens 96-99 22752108-0 2013 Patterns of alcohol use, their correlates, and impact in male drinkers: a population-based survey from Goa, India. Alcohols 12-19 tripartite motif containing 47 Homo sapiens 103-106 22553037-9 2012 However, unlike Octss2R, which activated a cAMP pathway, Octss1R likely inhibited cAMP production through inhibitory Goalpha. Cyclic AMP 82-86 tripartite motif containing 47 Homo sapiens 117-124 22629154-0 2012 Spatiotemporal distribution of harmful algal flora in the tropical estuarine complex of Goa, India. estuarine 67-76 tripartite motif containing 47 Homo sapiens 88-91 18832137-3 2008 METHODS: Data primarily from formative phases of studies on alcohol use patterns in the states of Delhi, Rajasthan and Goa are reported. Alcohols 60-67 tripartite motif containing 47 Homo sapiens 119-122 17172257-0 2007 Harmful alcohol use in Goa, India, and its associations with violence: a study in primary care. Alcohols 8-15 tripartite motif containing 47 Homo sapiens 23-26 17172257-9 2007 CONCLUSIONS: The male pattern of drinking in Goa is one of the high rates of abstention coupled with relatively high rates of harmful and dependent drinking in those who consume alcohol. Alcohols 178-185 tripartite motif containing 47 Homo sapiens 45-48 20300837-0 2011 Nitrate levels modulate denitrification activity in tropical mangrove sediments (Goa, India). Nitrates 0-7 tripartite motif containing 47 Homo sapiens 81-84 21110186-0 2010 Assessment of in-plant particulate matter and its toxic metals contents of sponge iron industry in Goa, India. Iron 82-86 tripartite motif containing 47 Homo sapiens 99-102 20531242-1 2010 OBJECTIVES: We previously reported a high incidence of alcohol-related acute pancreatitis (AP) in Goa, India, where country-made alcoholic products are consumed in addition to the commercially available alcoholic products. Alcohols 55-62 tripartite motif containing 47 Homo sapiens 98-101 20567894-0 2010 Validating alcohol use measures among male drinkers in Goa: implications for research on alcohol, sexual risk, and HIV in India. Alcohols 11-18 tripartite motif containing 47 Homo sapiens 55-58 20830937-0 2010 Denitrification: an important pathway for nitrous oxide production in tropical mangrove sediments (Goa, India). Nitrous Oxide 42-55 tripartite motif containing 47 Homo sapiens 99-102 16675310-1 2006 Resolution of racemic thioridazine obtained from Thioril tablets (Cipla Ltd., Goa, India) into its enantiomers has been achieved by HPLC using a beta-cyclodextrin (CD)-bonded stationary phase. Thioridazine 22-34 tripartite motif containing 47 Homo sapiens 78-81 16675310-1 2006 Resolution of racemic thioridazine obtained from Thioril tablets (Cipla Ltd., Goa, India) into its enantiomers has been achieved by HPLC using a beta-cyclodextrin (CD)-bonded stationary phase. Thioridazine 49-56 tripartite motif containing 47 Homo sapiens 78-81 15618020-0 2005 Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha. Guanosine Triphosphate 29-32 tripartite motif containing 47 Homo sapiens 96-103 15618020-0 2005 Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha. Guanosine Triphosphate 72-75 tripartite motif containing 47 Homo sapiens 96-103 15618020-1 2005 The effect of palmitoylation on the GTP-binding activity and conformation of Goalpha protein in hydrophobic and hydrophilic environments was studied. Guanosine Triphosphate 36-39 tripartite motif containing 47 Homo sapiens 77-84 15618020-2 2005 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate 66-69 tripartite motif containing 47 Homo sapiens 204-211 15618020-2 2005 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate 71-74 tripartite motif containing 47 Homo sapiens 204-211 15618020-2 2005 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Sulfur-35 80-84 tripartite motif containing 47 Homo sapiens 204-211 15618020-2 2005 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate 71-74 tripartite motif containing 47 Homo sapiens 204-211 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate 57-60 tripartite motif containing 47 Homo sapiens 77-84 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate 57-60 tripartite motif containing 47 Homo sapiens 128-135 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Diphosphate 61-64 tripartite motif containing 47 Homo sapiens 77-84 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Diphosphate 61-64 tripartite motif containing 47 Homo sapiens 128-135 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate 104-107 tripartite motif containing 47 Homo sapiens 77-84 15618020-6 2005 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate 104-107 tripartite motif containing 47 Homo sapiens 128-135 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. L-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID 27-30 tripartite motif containing 47 Homo sapiens 85-88 12670707-5 2003 Overexpression of Goalpha inhibited neurite extension in F11 cells and simultaneously repressed the stimulatory effect of cAMP on the Ca(v)2.2 gene expression to the basal level. Cyclic AMP 122-126 tripartite motif containing 47 Homo sapiens 18-25 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. Sulfates 0-7 tripartite motif containing 47 Homo sapiens 85-88 14519434-8 2003 Basal aaGTP binding was higher in RA than in LV for all Gialpha/Goalpha subtypes. GTP gamma-4-azidoanilide 6-11 tripartite motif containing 47 Homo sapiens 64-71 14519434-9 2003 The carbachol (10 micromol/l)-induced increase in aaGTP binding was significantly higher in RA than in LV for Goalpha-1/3 (336 +/- 95% of LV, n = 4) and for Gialpha-3 (211 +/- 83%), lower for Gialpha-2 (42 +/- 5%), and was similar in both regions for Goalpha-2 (130 +/- 62%). Carbachol 4-13 tripartite motif containing 47 Homo sapiens 110-117 14519434-9 2003 The carbachol (10 micromol/l)-induced increase in aaGTP binding was significantly higher in RA than in LV for Goalpha-1/3 (336 +/- 95% of LV, n = 4) and for Gialpha-3 (211 +/- 83%), lower for Gialpha-2 (42 +/- 5%), and was similar in both regions for Goalpha-2 (130 +/- 62%). Carbachol 4-13 tripartite motif containing 47 Homo sapiens 251-258 14519434-9 2003 The carbachol (10 micromol/l)-induced increase in aaGTP binding was significantly higher in RA than in LV for Goalpha-1/3 (336 +/- 95% of LV, n = 4) and for Gialpha-3 (211 +/- 83%), lower for Gialpha-2 (42 +/- 5%), and was similar in both regions for Goalpha-2 (130 +/- 62%). GTP gamma-4-azidoanilide 50-55 tripartite motif containing 47 Homo sapiens 110-117 14519434-9 2003 The carbachol (10 micromol/l)-induced increase in aaGTP binding was significantly higher in RA than in LV for Goalpha-1/3 (336 +/- 95% of LV, n = 4) and for Gialpha-3 (211 +/- 83%), lower for Gialpha-2 (42 +/- 5%), and was similar in both regions for Goalpha-2 (130 +/- 62%). GTP gamma-4-azidoanilide 50-55 tripartite motif containing 47 Homo sapiens 251-258 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. formic acid 142-149 tripartite motif containing 47 Homo sapiens 85-88 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. Butyrates 169-177 tripartite motif containing 47 Homo sapiens 85-88 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. Ethanol 179-186 tripartite motif containing 47 Homo sapiens 85-88 12269474-1 2002 Sulfate-reducing bacteria (SRB) HSR1, HSR4, and HSR14 isolated from the salt pans of Goa grew best at 90-100/1000 salinity on substrates like formate, acetate, lactate, butyrate, ethanol and benzoate. Benzoates 191-199 tripartite motif containing 47 Homo sapiens 85-88 11862328-0 2002 Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain. Suramin 23-30 tripartite motif containing 47 Homo sapiens 175-182 11832659-10 2001 Immunoblocking of G(q/11)alpha, however, reduced the stimulatory effect of TRH on PL-C activation by some 65%, while an antiserum against G(o)alpha partly counteracted the inhibitory effect of bromocriptine (10 microM) on TRH stimulated PL-C activity. Bromocriptine 193-206 tripartite motif containing 47 Homo sapiens 138-147 11318657-6 2001 LGN-585-642, Pcp2, and RapIGAPII-23-131 inhibited the rates of spontaneous GTPgammaS binding and blocked GDP release from Gialpha(1) and Goalpha. Guanosine Diphosphate 105-108 tripartite motif containing 47 Homo sapiens 137-144 10510311-0 1999 Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactions. bbxxb 92-97 tripartite motif containing 47 Homo sapiens 173-182 10510311-5 1999 Enhanced agonist-independent and agonist-dependent 5-HT(1B) receptor activation was provided by co-expression of a pertussis toxin-resistant rat G(o)alpha Cys(351)-->Ile protein. Cysteine 155-158 tripartite motif containing 47 Homo sapiens 145-154 9299393-2 1997 The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors. Tetradecanoylphorbol Acetate 56-87 tripartite motif containing 47 Homo sapiens 172-175 9359829-7 1997 We characterized N-terminal mutants of Go alpha with known G beta gamma-binding properties for the ability to interact with phospholipid vesicles and membranes prepared from cultured cells (acceptor membranes). Phospholipids 124-136 tripartite motif containing 47 Homo sapiens 39-47 9359829-11 1997 Disrupting the N-terminal alpha-helix of Go alpha with a proline point mutation at Arg-9 (R9P) does not affect interactions with G beta gamma on sucrose-density gradients but significantly reduces acceptor membrane binding. Proline 57-64 tripartite motif containing 47 Homo sapiens 41-49 9359829-11 1997 Disrupting the N-terminal alpha-helix of Go alpha with a proline point mutation at Arg-9 (R9P) does not affect interactions with G beta gamma on sucrose-density gradients but significantly reduces acceptor membrane binding. Arginine 83-86 tripartite motif containing 47 Homo sapiens 41-49 9359829-15 1997 The binding of Go alpha and mutants translated in vitro to liposomes indicates that Go alpha preferentially binds to neutral phospholipids (phosphatidylcholine). Phospholipids 125-138 tripartite motif containing 47 Homo sapiens 15-23 9359829-15 1997 The binding of Go alpha and mutants translated in vitro to liposomes indicates that Go alpha preferentially binds to neutral phospholipids (phosphatidylcholine). Phospholipids 125-138 tripartite motif containing 47 Homo sapiens 84-92 9359829-15 1997 The binding of Go alpha and mutants translated in vitro to liposomes indicates that Go alpha preferentially binds to neutral phospholipids (phosphatidylcholine). Phosphatidylcholines 140-159 tripartite motif containing 47 Homo sapiens 15-23 9359829-15 1997 The binding of Go alpha and mutants translated in vitro to liposomes indicates that Go alpha preferentially binds to neutral phospholipids (phosphatidylcholine). Phosphatidylcholines 140-159 tripartite motif containing 47 Homo sapiens 84-92 9454573-1 1998 Single tryptophan mutants of a histidine-tagged G(o)alpha (W132F and W212F) were prepared to examine the functional and spectroscopic role of tryptophan in G(o)alpha. Histidine 31-40 tripartite motif containing 47 Homo sapiens 48-57 9544801-6 1998 Morphine, DAMGO and endomorphin I each activated Gi1 alpha/Gi2 alpha, Go alpha and Gi3 alpha to a similar extent, but not Gq alpha/G11 alpha or Gs alpha in HEK membranes. Morphine 0-8 tripartite motif containing 47 Homo sapiens 70-78 9299393-2 1997 The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors. Tetradecanoylphorbol Acetate 89-92 tripartite motif containing 47 Homo sapiens 172-175 9299393-2 1997 The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors. Nitrogen 130-131 tripartite motif containing 47 Homo sapiens 172-175 9299393-2 1997 The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors. myristoyl glycinal diethylacetal 132-164 tripartite motif containing 47 Homo sapiens 172-175 8626678-3 1996 The third cytosolic loop (i3) of edg-1 associates with G(i) alpha and G(o) alpha polypeptides in a guanosine 5"-O-(thiotriphosphate)-sensitive manner. guanosine 5"-o- 99-114 tripartite motif containing 47 Homo sapiens 70-80 8626678-3 1996 The third cytosolic loop (i3) of edg-1 associates with G(i) alpha and G(o) alpha polypeptides in a guanosine 5"-O-(thiotriphosphate)-sensitive manner. thiotriphosphate 115-131 tripartite motif containing 47 Homo sapiens 70-80 7686903-10 1993 Moreover, specific antibodies raised against the carboxyl terminus of G(o) alpha reversed in a dose-dependent manner the inhibition by mastoparan on catecholamine release and the stimulation by mastoparan of chromaffin granule-associated G proteins. Catecholamines 149-162 tripartite motif containing 47 Homo sapiens 70-80 8139926-1 1994 Go alpha a guanine nucleotide-binding (G) protein abundant in brain and other neural tissues, has been implicated in ion channel regulation. Guanine Nucleotides 11-29 tripartite motif containing 47 Homo sapiens 0-8 8617747-7 1996 The relative maximal fluorescence levels observed upon binding to recombinant myristoylated Goalpha (myrGoalpha) and myrGialpha1 were: mGTPgammaS > MANT-5"-guanylyl-imidodiphosphate > MANT-guanylyl-(beta,gamma-methylene)-diphosphonate > MANT-guanosine 5"-O-2-(thio)diphosphate. N-methyl-3'-O-anthranoyl guanosine 5'-O-(3-thiotriphosphate) 135-145 tripartite motif containing 47 Homo sapiens 92-99 8617747-7 1996 The relative maximal fluorescence levels observed upon binding to recombinant myristoylated Goalpha (myrGoalpha) and myrGialpha1 were: mGTPgammaS > MANT-5"-guanylyl-imidodiphosphate > MANT-guanylyl-(beta,gamma-methylene)-diphosphonate > MANT-guanosine 5"-O-2-(thio)diphosphate. mant-5"-guanylyl-imidodiphosphate 151-184 tripartite motif containing 47 Homo sapiens 92-99 8617747-7 1996 The relative maximal fluorescence levels observed upon binding to recombinant myristoylated Goalpha (myrGoalpha) and myrGialpha1 were: mGTPgammaS > MANT-5"-guanylyl-imidodiphosphate > MANT-guanylyl-(beta,gamma-methylene)-diphosphonate > MANT-guanosine 5"-O-2-(thio)diphosphate. mant-guanylyl-(beta,gamma-methylene)-diphosphonate 190-240 tripartite motif containing 47 Homo sapiens 92-99 8617747-7 1996 The relative maximal fluorescence levels observed upon binding to recombinant myristoylated Goalpha (myrGoalpha) and myrGialpha1 were: mGTPgammaS > MANT-5"-guanylyl-imidodiphosphate > MANT-guanylyl-(beta,gamma-methylene)-diphosphonate > MANT-guanosine 5"-O-2-(thio)diphosphate. mant-guanosine 5"-o-2-(thio)diphosphate 246-285 tripartite motif containing 47 Homo sapiens 92-99 1518856-4 1992 Mastoparan enhances the GTPase activity of recombinant G(o) alpha 5-fold in phospholipid vesicles. Phospholipids 76-88 tripartite motif containing 47 Homo sapiens 55-65 34359486-1 2021 A novel sorbent based on the ZrO2 nanoparticles and poly(diallyldimethylammonium chloride)-modified graphene oxide aerogel-grafted stainless steel mesh (ZrO2/PDDA-GOA-SSM) was used for the extraction and detection of organophosphorus pesticides (OPPs). poly-N,N-dimethyl-N,N-diallylammonium chloride 52-90 tripartite motif containing 47 Homo sapiens 163-166 2121545-8 1990 Treatment with MK-801 caused a significant attenuation of the decrease in Go alpha mRNA, indicating the involvement of NMDA receptors in this response. Dizocilpine Maleate 15-21 tripartite motif containing 47 Homo sapiens 74-82 2121288-2 1990 The efficiency of Go alpha binding to the cytoskeleton components depends on the nature of the guanyl nucleotides [GDP-beta-S, Gpp (NH) p] present in the incubation medium. guanyl nucleotides 95-113 tripartite motif containing 47 Homo sapiens 18-26 2121288-2 1990 The efficiency of Go alpha binding to the cytoskeleton components depends on the nature of the guanyl nucleotides [GDP-beta-S, Gpp (NH) p] present in the incubation medium. guanosine 5'-O-(2-thiodiphosphate) 115-125 tripartite motif containing 47 Homo sapiens 18-26 2121288-2 1990 The efficiency of Go alpha binding to the cytoskeleton components depends on the nature of the guanyl nucleotides [GDP-beta-S, Gpp (NH) p] present in the incubation medium. Guanylyl Imidodiphosphate 127-137 tripartite motif containing 47 Homo sapiens 18-26 2121288-4 1990 ATP diminishes the degree Go alpha adsorption. Adenosine Triphosphate 0-3 tripartite motif containing 47 Homo sapiens 26-34 34433666-5 2021 As functional analyses, we manipulated TRIM47 expression in estrogen receptor-positive breast cancer cells MCF-7 and its 4-hydroxytamoxifen (OHT)-resistant derivative OHTR, which was established in a long-term culture with OHT. afimoxifene 121-139 tripartite motif containing 47 Homo sapiens 39-45 34433666-5 2021 As functional analyses, we manipulated TRIM47 expression in estrogen receptor-positive breast cancer cells MCF-7 and its 4-hydroxytamoxifen (OHT)-resistant derivative OHTR, which was established in a long-term culture with OHT. oht 141-144 tripartite motif containing 47 Homo sapiens 39-45 34433666-7 2021 MCF-7 cells acquired tamoxifen resistance by overexpressing exogenous TRIM47. Tamoxifen 21-30 tripartite motif containing 47 Homo sapiens 70-76 34433666-10 2021 As an underlying mechanism, we showed TRIM47-dependent lysine 27-linked polyubiquitination of PKC-epsilon. Lysine 55-61 tripartite motif containing 47 Homo sapiens 38-44 1899283-1 1991 Go alpha, (gene symbol GNA01), a member of the signal-transducing guanine nucleotide-binding (G) protein family, has been implicated in ion channel regulation. Guanine Nucleotides 66-84 tripartite motif containing 47 Homo sapiens 0-8 34881663-1 2021 This is an ethnographic study that examines the experiences of peer counsellors in the Thinking Healthy Programme Peer-delivered (THPP), a randomized controlled trial of a psychological intervention for perinatal depression in Goa, India. flopropione 130-134 tripartite motif containing 47 Homo sapiens 227-230 34359486-1 2021 A novel sorbent based on the ZrO2 nanoparticles and poly(diallyldimethylammonium chloride)-modified graphene oxide aerogel-grafted stainless steel mesh (ZrO2/PDDA-GOA-SSM) was used for the extraction and detection of organophosphorus pesticides (OPPs). graphene oxide 100-114 tripartite motif containing 47 Homo sapiens 163-166 34359486-1 2021 A novel sorbent based on the ZrO2 nanoparticles and poly(diallyldimethylammonium chloride)-modified graphene oxide aerogel-grafted stainless steel mesh (ZrO2/PDDA-GOA-SSM) was used for the extraction and detection of organophosphorus pesticides (OPPs). organophosphorus 217-233 tripartite motif containing 47 Homo sapiens 163-166