PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 31556760-5 2019 The patient was treated with topical dorzolamide and showed significant improvement in the degree of macular cysts.Conclusion: Mutations in KIZ can present with a predominantly macular phenotype and develop cystoid macular changes responsive to carbonic anhydrase inhibitor treatment. dorzolamide 37-48 kizuna centrosomal protein Homo sapiens 140-143 33000253-7 2020 Functional analyses demonstrated that a miR-653 inhibitor promoted short hairpin PLK1S1-attenuated cell proliferation, invasion and sorafenib resistance of RCC cells. Sorafenib 132-141 kizuna centrosomal protein Homo sapiens 81-87 33000253-11 2020 In conclusion, the present study revealed that PLK1S1 promoted tumor progression and sorafenib resistance in RCC through regulation of the miR-653/CXCR5 axis, which may offer a novel treatment strategy for patients with RCC. Sorafenib 85-94 kizuna centrosomal protein Homo sapiens 47-53