PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
11014304-2	2000	Chemical modification of potato apyrase suggests that tryptophan residues are close to the nucleotide binding site.	Tryptophan	54-64	apyrase	Solanum tuberosum	32-39
18772187-3	2008	(i) Incubation of intact tuber slices with ATP led to the formation of ADP, AMP, adenosine, adenine and ribose, indicating operation of apyrase, 5"-nucleotidase and nucleosidase.	Adenosine Triphosphate	43-46	apyrase	Solanum tuberosum	136-143
18772187-3	2008	(i) Incubation of intact tuber slices with ATP led to the formation of ADP, AMP, adenosine, adenine and ribose, indicating operation of apyrase, 5"-nucleotidase and nucleosidase.	Adenosine Monophosphate	76-79	apyrase	Solanum tuberosum	136-143
18772187-3	2008	(i) Incubation of intact tuber slices with ATP led to the formation of ADP, AMP, adenosine, adenine and ribose, indicating operation of apyrase, 5"-nucleotidase and nucleosidase.	Adenosine	81-90	apyrase	Solanum tuberosum	136-143
18772187-3	2008	(i) Incubation of intact tuber slices with ATP led to the formation of ADP, AMP, adenosine, adenine and ribose, indicating operation of apyrase, 5"-nucleotidase and nucleosidase.	Adenine	92-99	apyrase	Solanum tuberosum	136-143
18772187-3	2008	(i) Incubation of intact tuber slices with ATP led to the formation of ADP, AMP, adenosine, adenine and ribose, indicating operation of apyrase, 5"-nucleotidase and nucleosidase.	Ribose	104-110	apyrase	Solanum tuberosum	136-143
18480378-7	2008	DNA microarrays revealed that decreased expression of apyrase leads to increased levels of transcripts coding for cell wall proteins involved in growth and genes involved in energy transfer and starch synthesis.	Starch	194-200	apyrase	Solanum tuberosum	54-61
18305207-3	2008	Inducible apyrase expression in potato tubers, for a period of 24 h, resulted in a decrease in the ATP-content and the ATP-ADP ratio in the tubers.	Adenosine Triphosphate	99-102	apyrase	Solanum tuberosum	10-17
18305207-3	2008	Inducible apyrase expression in potato tubers, for a period of 24 h, resulted in a decrease in the ATP-content and the ATP-ADP ratio in the tubers.	atp-adp	119-126	apyrase	Solanum tuberosum	10-17
18305207-5	2008	Constitutive tuber-specific apyrase expression did not lead to a reduction of ATP, but rather a decrease in ADP and an increase in AMP levels.	Adenosine Diphosphate	108-111	apyrase	Solanum tuberosum	28-35
18305207-5	2008	Constitutive tuber-specific apyrase expression did not lead to a reduction of ATP, but rather a decrease in ADP and an increase in AMP levels.	Adenosine Monophosphate	131-134	apyrase	Solanum tuberosum	28-35
18005473-1	2008	A Leishmania (Leishmania) amazonensis ATP diphosphohydrolase isoform was partially purified from plasma membrane of promastigotes by preparative non-denaturing polyacrylamide gel electrophoresis.	polyacrylamide	160-174	apyrase	Solanum tuberosum	38-60
18005473-2	2008	SDS-PAGE followed by Western blots developed with polyclonal anti-potato apyrase antibodies identified diffuse bands of about 58-63 kDa, possibly glycosylated forms of this protein.	Sodium Dodecyl Sulfate	0-3	apyrase	Solanum tuberosum	73-80
11515379-5	2001	We used the method to study the inhibitory effects of various compounds on the ATPase activity of potato apyrase, measured with 500 nM ATP.	Adenosine Triphosphate	79-82	apyrase	Solanum tuberosum	105-112
11515379-7	2001	Under our assay conditions, vanadate inhibited about 98% of the ATPase activity of the potato apyrase at a concentration of 250 microM.	Vanadates	28-36	apyrase	Solanum tuberosum	94-101
20721477-2	2010	The analyses for each patient cured (n = 14) after treatment (AT) with praziquantel revealed variable IgG1 and IgG4 reactivity against potato apyrase.	Praziquantel	71-83	apyrase	Solanum tuberosum	142-149
19462288-8	2009	Depletion of ssATP by the Solanum tuberosum apyrase, a 49 kDa, non-cell permeant enzyme, significantly reduced the ATP content measured by an adapted luminescence-ATP assay from which all permeabilizing agents were excluded.	ssatp	13-18	apyrase	Solanum tuberosum	44-51
19462288-8	2009	Depletion of ssATP by the Solanum tuberosum apyrase, a 49 kDa, non-cell permeant enzyme, significantly reduced the ATP content measured by an adapted luminescence-ATP assay from which all permeabilizing agents were excluded.	Adenosine Triphosphate	15-18	apyrase	Solanum tuberosum	44-51
19462288-8	2009	Depletion of ssATP by the Solanum tuberosum apyrase, a 49 kDa, non-cell permeant enzyme, significantly reduced the ATP content measured by an adapted luminescence-ATP assay from which all permeabilizing agents were excluded.	Adenosine Triphosphate	115-118	apyrase	Solanum tuberosum	44-51
19462288-12	2009	Apyrase only altered the proteasomal core activities slightly, since these activities are not directly dependent on external ATP.	Adenosine Triphosphate	125-128	apyrase	Solanum tuberosum	0-7
15896365-1	2005	Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate.	Nucleosides	68-79	apyrase	Solanum tuberosum	0-7
15896365-1	2005	Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate.	Nucleosides	68-79	apyrase	Solanum tuberosum	8-30
15896365-1	2005	Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate.	Phosphates	141-155	apyrase	Solanum tuberosum	0-7
15896365-1	2005	Apyrase/ATP-diphosphohydrolase hydrolyzes di- and triphosphorylated nucleosides in the presence of a bivalent ion with sequential release of orthophosphate.	Phosphates	141-155	apyrase	Solanum tuberosum	8-30
15389120-2	2004	Apyrase (CD39) takes part of a family of ecto-enzymes that hydrolyze adenosine diphosphate and adenosine triphosphate.	Adenosine Diphosphate	69-90	apyrase	Solanum tuberosum	0-7
15389120-2	2004	Apyrase (CD39) takes part of a family of ecto-enzymes that hydrolyze adenosine diphosphate and adenosine triphosphate.	Adenosine Triphosphate	95-117	apyrase	Solanum tuberosum	0-7
11014304-3	2000	Kd values (+/- Ca2+) for the complexes of apyrase with the non-hydrolysable phosphonate adenine nucleotide analogues, adenosine 5"-(beta,gamma-methylene) triphosphate and adenosine 5"-(alpha,beta-methylene) diphosphate, were obtained from quenching of the intrinsic enzyme fluorescence.	phosphonate adenine nucleotide	76-106	apyrase	Solanum tuberosum	42-49
11014304-3	2000	Kd values (+/- Ca2+) for the complexes of apyrase with the non-hydrolysable phosphonate adenine nucleotide analogues, adenosine 5"-(beta,gamma-methylene) triphosphate and adenosine 5"-(alpha,beta-methylene) diphosphate, were obtained from quenching of the intrinsic enzyme fluorescence.	5'-adenylyl (beta,gamma-methylene)diphosphonate	118-166	apyrase	Solanum tuberosum	42-49
11014304-3	2000	Kd values (+/- Ca2+) for the complexes of apyrase with the non-hydrolysable phosphonate adenine nucleotide analogues, adenosine 5"-(beta,gamma-methylene) triphosphate and adenosine 5"-(alpha,beta-methylene) diphosphate, were obtained from quenching of the intrinsic enzyme fluorescence.	alpha,beta-methyleneadenosine 5'-diphosphate	171-218	apyrase	Solanum tuberosum	42-49
11014304-5	2000	1,N6-ethenoadenosine triphosphate and 1,N6-ethenoadenosine diphosphate) were hydrolysed by apyrase in the presence of Ca2+, indicating binding to the active site.	1,n6-ethenoadenosine triphosphate	0-33	apyrase	Solanum tuberosum	91-98
11014304-5	2000	1,N6-ethenoadenosine triphosphate and 1,N6-ethenoadenosine diphosphate) were hydrolysed by apyrase in the presence of Ca2+, indicating binding to the active site.	1,N(6)-ethenoadenosine diphosphate	38-70	apyrase	Solanum tuberosum	91-98
34608744-6	2021	Cardamonin achieved a significant inhibition of the apyrase activity and the three-dimensional structure of the potato apyrase, obtained by homology modeling, showed that cardamonin may interact mainly through hydrogen bonds.	cardamonin	0-10	apyrase	Solanum tuberosum	52-59
34608744-6	2021	Cardamonin achieved a significant inhibition of the apyrase activity and the three-dimensional structure of the potato apyrase, obtained by homology modeling, showed that cardamonin may interact mainly through hydrogen bonds.	cardamonin	0-10	apyrase	Solanum tuberosum	119-126
34608744-6	2021	Cardamonin achieved a significant inhibition of the apyrase activity and the three-dimensional structure of the potato apyrase, obtained by homology modeling, showed that cardamonin may interact mainly through hydrogen bonds.	cardamonin	171-181	apyrase	Solanum tuberosum	52-59
34608744-6	2021	Cardamonin achieved a significant inhibition of the apyrase activity and the three-dimensional structure of the potato apyrase, obtained by homology modeling, showed that cardamonin may interact mainly through hydrogen bonds.	cardamonin	171-181	apyrase	Solanum tuberosum	119-126
34608744-6	2021	Cardamonin achieved a significant inhibition of the apyrase activity and the three-dimensional structure of the potato apyrase, obtained by homology modeling, showed that cardamonin may interact mainly through hydrogen bonds.	Hydrogen	210-218	apyrase	Solanum tuberosum	119-126
34608744-7	2021	Molecular docking studies corroborate with the action of cardamonin in binding and inhibiting both potato apyrase and S. mansoni NTPDases.	cardamonin	57-67	apyrase	Solanum tuberosum	106-113
32663559-0	2020	Screening of plant derived chalcones on the inhibition of potato apyrase: Potential protein biotechnological applications in health.	Chalcones	27-36	apyrase	Solanum tuberosum	65-72
203267-0	1977	Hydrolysis of synthetic pyrophosphoric esters by an isoenzyme of apyrase from Solanum tuberosum.	pyrophosphoric esters	24-45	apyrase	Solanum tuberosum	65-72
13426119-0	1957	The mechanism of hydrolysis of adenosine di- and tri-phosphate catalysed by potato apyrase.	adenosine di- and tri-phosphate	31-62	apyrase	Solanum tuberosum	83-90
35631657-4	2022	In this study, we screen NTPDases inhibitors from Centella erecta (Apiaceae) using an ultrafiltration combined UHPLC-QTOF-MS method and potato apyrase, identifying asiaticoside as one of the apyrase-binding compounds.	asiaticoside	164-176	apyrase	Solanum tuberosum	191-198
35631657-5	2022	After isolation of asiaticoside from C. erecta extract, we assessed its in vivo antischistosomal activities against Schistosoma mansoni worms and its in vitro enzymatic apyrase inhibition.	asiaticoside	19-31	apyrase	Solanum tuberosum	169-176
35631657-6	2022	Also, molecular docking analysis of asiaticoside against potato apyrase, S. mansoni NTPDases 1 and 2 were performed.	asiaticoside	36-48	apyrase	Solanum tuberosum	64-71
35631657-7	2022	Asiaticoside showed a significant in vitro apyrase inhibition and molecular docking studies corroborate with its possible actions in potato apyrase and S. mansoni NTPDases.	asiaticoside	0-12	apyrase	Solanum tuberosum	43-50
35631657-7	2022	Asiaticoside showed a significant in vitro apyrase inhibition and molecular docking studies corroborate with its possible actions in potato apyrase and S. mansoni NTPDases.	asiaticoside	0-12	apyrase	Solanum tuberosum	140-147
1211467-5	1975	Addition of low concentrations of thrombin (0.1 U/ml) caused retraction associated with a considerable release of adenine nucleotides that was inhibited by potato apyrase.	Adenine Nucleotides	114-133	apyrase	Solanum tuberosum	163-170
13198968-0	1954	[Studies on apyrase and phosphatase activities in potato tuber growing in various conditions according to maturing of tubers and their relation to formation of starch].	Starch	160-166	apyrase	Solanum tuberosum	12-19
32663559-4	2020	In this study, we investigated the in vitro potential of synthetic chalcones on the inhibition of potato apyrase purified from Solanum tuberosum.	Chalcones	67-76	apyrase	Solanum tuberosum	105-112
32663559-6	2020	Five out of the eight chemically synthetized chalcones analyzed in this study showed significant inhibition of the apyrase activity.	Chalcones	45-54	apyrase	Solanum tuberosum	115-122
32663559-9	2020	Our results with the potato apyrase inhibition with the synthetic chalcones suggest that these compounds may use as potential lead candidates for the treatment of some diseases associated with nucleotides.	Chalcones	66-75	apyrase	Solanum tuberosum	28-35
29801599-0	2018	Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods.	Adenosine Triphosphate	66-69	apyrase	Solanum tuberosum	48-55
29801599-6	2018	In light of this, we have developed a recombinant Shigella flexneri apyrase (RSFA) enzyme and analysed its ATP depletion potential with five commercial biochemical sources including potato apyrase, acid phosphatase, alkaline phosphatase, hexokinase and glycerol kinase.	Adenosine Triphosphate	107-110	apyrase	Solanum tuberosum	68-75