PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 30297535-6 2018 Treatment with AZ0108, a PARP6 inhibitor with a favorable pharmacokinetic profile, potently induced the MPS phenotype, leading to apoptosis in a subset of breast cancer cells in vitro and antitumor effects in vivo. AZ0108 15-21 poly(ADP-ribose) polymerase family member 6 Homo sapiens 25-30 30297535-9 2018 Together, these results establish proof-of-concept antitumor efficacy through PARP6 inhibition and highlight a novel function of PARP6 in maintaining centrosome integrity via direct ADP-ribosylation of Chk1 and modulation of its activity. Adenosine Diphosphate 182-185 poly(ADP-ribose) polymerase family member 6 Homo sapiens 129-134 31938348-1 2018 Poly (ADP-ribose) polymerases 6 (PARP6) is a novel member of the PARP family. Poly Adenosine Diphosphate Ribose 0-17 poly(ADP-ribose) polymerase family member 6 Homo sapiens 33-38 31938348-1 2018 Poly (ADP-ribose) polymerases 6 (PARP6) is a novel member of the PARP family. Poly Adenosine Diphosphate Ribose 0-17 poly(ADP-ribose) polymerase family member 6 Homo sapiens 33-37 26934315-1 2016 Poly (ADP-ribose) polymerases (PARPs) are enzymes that transfer ADP-ribose groups to target proteins and are involved in a variety of biological processes. Adenosine Diphosphate 6-9 poly(ADP-ribose) polymerase family member 6 Homo sapiens 31-36 26934315-1 2016 Poly (ADP-ribose) polymerases (PARPs) are enzymes that transfer ADP-ribose groups to target proteins and are involved in a variety of biological processes. Ribose 10-16 poly(ADP-ribose) polymerase family member 6 Homo sapiens 31-36 11241606-0 2001 Combinatorial Libraries of Metal-Ligand Assemblies with an Encapsulated Guest Molecule Coordination Number Incommensurate Cluster Formation, Part 17. Metals 27-32 poly(ADP-ribose) polymerase family member 6 Homo sapiens 141-148 11353485-0 2001 Metallacoronates or One-Dimensional Polymers through Self-Assembly-Influence of Templates and Hydrogen Bonding on Product Formation Chelate Complexes, Part 17. metallacoronates 0-16 poly(ADP-ribose) polymerase family member 6 Homo sapiens 151-158 11353485-0 2001 Metallacoronates or One-Dimensional Polymers through Self-Assembly-Influence of Templates and Hydrogen Bonding on Product Formation Chelate Complexes, Part 17. Polymers 36-44 poly(ADP-ribose) polymerase family member 6 Homo sapiens 151-158 11353485-0 2001 Metallacoronates or One-Dimensional Polymers through Self-Assembly-Influence of Templates and Hydrogen Bonding on Product Formation Chelate Complexes, Part 17. Hydrogen 94-102 poly(ADP-ribose) polymerase family member 6 Homo sapiens 151-158 18710813-1 2008 Part 17: Synthesis and antimicrobial activity of novel ketoconazole-NO-donor hybrid compounds. ketoconazole-no 55-70 poly(ADP-ribose) polymerase family member 6 Homo sapiens 0-7 18534847-1 2008 Part 17: a cross-target SAR approach: affinities of azecine-styled ligands for 5-HT(2A) versus D1 and D2 receptors. Azecine 52-59 poly(ADP-ribose) polymerase family member 6 Homo sapiens 0-7 11093237-0 2000 A New Highly Efficient Catalyst System for the Coupling of Nonactivated and Deactivated Aryl Chlorides with Arylboronic Acids Palladium-Catalyzed Reactions for Fine Chemical Synthesis, Part 17. aryl chlorides 88-102 poly(ADP-ribose) polymerase family member 6 Homo sapiens 185-192 11093237-0 2000 A New Highly Efficient Catalyst System for the Coupling of Nonactivated and Deactivated Aryl Chlorides with Arylboronic Acids Palladium-Catalyzed Reactions for Fine Chemical Synthesis, Part 17. arylboronic acids palladium 108-135 poly(ADP-ribose) polymerase family member 6 Homo sapiens 185-192 10976519-1 2000 Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes. acyloxymethyl carbamate 44-67 poly(ADP-ribose) polymerase family member 6 Homo sapiens 0-7 10976519-1 2000 Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes. Triazenes 94-103 poly(ADP-ribose) polymerase family member 6 Homo sapiens 0-7 450957-1 1979 Part 17: On the effect of macromolecular adjuvants on the dissolution rate of chlorpromazine from dosage forms (author"s transl)]. Chlorpromazine 78-92 poly(ADP-ribose) polymerase family member 6 Homo sapiens 0-7