PMID-sentid Pub_year Sent_text comp_official_name comp_offset protein_name organism prot_offset 24655971-0 2014 Usefulness and safety of high-dose mizoribine on ABO-incompatible living related kidney transplantation using anti-CD20 and anti-CD25 antibodies without splenectomy: 3-year results. mizoribine 35-45 interferon stimulated exonuclease gene 20 Homo sapiens 129-133 24732038-7 2014 Translation of these in vitro findings to in vivo effects, however, were mixed as minocycline significantly reduced markers of activation and activation-induced cell death (CD25, Fas, caspase-3) but did not affect expression of IFNbeta or the IFN-stimulated genes IDO1, FasL, or Mx in the spleens of chronically SIV-infected pigtailed macaques. Minocycline 82-93 interferon stimulated exonuclease gene 20 Homo sapiens 173-177 23017670-4 2013 Sixteen hours PMA/Ionomycin stimulation induced iTreg subsets with the phenotype CD4(+)CD25(+)Foxp3(+), CD4(+)IFNgamma(+)Foxp3(+) and CD4(+)CD25(+)IFNgamma(+) co-expressing CD95, CD152, CD178, CD279, Granzyme A, Granzyme B, Perforin, IL-10, and TGFbeta(1). Ionomycin 18-27 interferon stimulated exonuclease gene 20 Homo sapiens 87-91 23466550-5 2013 Among the tested media, X-VIVO 20 supplemented with HS produced the highest yield after 17days of in vitro expansion (a median of 86-fold expansion, range 30-1365) and highest level of FoxP3 expression (a median of 66.8% of positive cells, range 56-84.8%) in CD4(+) CD25(hi)CD127(lo/neg) FACS sorted polyclonal Tregs. hassio 52-54 interferon stimulated exonuclease gene 20 Homo sapiens 266-270 23017670-4 2013 Sixteen hours PMA/Ionomycin stimulation induced iTreg subsets with the phenotype CD4(+)CD25(+)Foxp3(+), CD4(+)IFNgamma(+)Foxp3(+) and CD4(+)CD25(+)IFNgamma(+) co-expressing CD95, CD152, CD178, CD279, Granzyme A, Granzyme B, Perforin, IL-10, and TGFbeta(1). Ionomycin 18-27 interferon stimulated exonuclease gene 20 Homo sapiens 140-144 22130159-5 2012 Furthermore, the CD25-enriched cells lost alloreactivity in H-thymidine proliferation assays and showed highly effective (median, 98%) suppression of alloreactivity in all evaluated donors. h-thymidine 60-71 interferon stimulated exonuclease gene 20 Homo sapiens 17-21 23559897-3 2013 In the present study, we re-evaluated the effect of ribavirin on Foxp3(+)CD4(+)CD25(+) Treg cells from normal donors. Ribavirin 52-61 interferon stimulated exonuclease gene 20 Homo sapiens 79-83 21750147-0 2011 Aurintricarboxylic acid promotes the conversion of naive CD4+CD25- T cells into Foxp3-expressing regulatory T cells. Aurintricarboxylic Acid 0-23 interferon stimulated exonuclease gene 20 Homo sapiens 61-65 22310599-0 2012 The efficacy and safety of high-dose mizoribine in ABO-incompatible kidney transplantation using anti-CD20 and anti-CD25 antibody without splenectomy treatment. mizoribine 37-47 interferon stimulated exonuclease gene 20 Homo sapiens 116-120 21496404-8 2011 There was a statistically significant difference for the Midline Estimating Statistic of Rhythm (MESOR) of CD3 (p=0.001), CD25 (p=0.003) and gammadelta-TCR-expressing cells (p=0.004), higher in the elderly, and for the MESOR of HLA-DR (p=0.002) and CD20 (p=0.002) higher in the young and middle-aged subjects. midline 57-64 interferon stimulated exonuclease gene 20 Homo sapiens 122-126 21297354-3 2011 Out of 35,035 human genes, Cd enhanced the expression of 3 metallothionein (MT)-I subisoform genes, including MT1E, MT1H and MT1B, and reduced the expression of 12 genes, including ISG20 and TK1, 2-fold or greater. Cadmium 27-29 interferon stimulated exonuclease gene 20 Homo sapiens 181-186 21832855-6 2011 RESULTS: Treatment of cells with poly (I:C) induced the expression of ISG20. Poly I-C 33-42 interferon stimulated exonuclease gene 20 Homo sapiens 70-75 21832855-9 2011 The poly (I:C)-induced expressions of IFN-beta and ISG20 were inhibited by dexamethasone. Dexamethasone 75-88 interferon stimulated exonuclease gene 20 Homo sapiens 51-56 21832855-10 2011 Transfection of mesangial cells with poly (I:C) or 5"-triphosphate single-stranded RNA as a complex with cationic lipid also induced the expression of ISG20, and this was inhibited by knockdown of retinoic acid-inducible gene-I (RIG-I). 5"-triphosphate 51-66 interferon stimulated exonuclease gene 20 Homo sapiens 151-156 21832855-10 2011 Transfection of mesangial cells with poly (I:C) or 5"-triphosphate single-stranded RNA as a complex with cationic lipid also induced the expression of ISG20, and this was inhibited by knockdown of retinoic acid-inducible gene-I (RIG-I). poly 37-41 interferon stimulated exonuclease gene 20 Homo sapiens 151-156 21832855-11 2011 CONCLUSION: Poly (I:C) induces the expression of ISG20 in mesangial cells. Poly I-C 12-21 interferon stimulated exonuclease gene 20 Homo sapiens 49-54 21832855-13 2011 TLR3, IRF3 and de novo synthesized IFN-beta may mediate the poly (I:C)-induced expression of ISG20, and RIG-I may mediate ISG20 expression induced by poly (I:C)/cationic lipid complex. Poly I-C 60-70 interferon stimulated exonuclease gene 20 Homo sapiens 93-98 21832855-13 2011 TLR3, IRF3 and de novo synthesized IFN-beta may mediate the poly (I:C)-induced expression of ISG20, and RIG-I may mediate ISG20 expression induced by poly (I:C)/cationic lipid complex. Poly I-C 150-160 interferon stimulated exonuclease gene 20 Homo sapiens 93-98 21832855-13 2011 TLR3, IRF3 and de novo synthesized IFN-beta may mediate the poly (I:C)-induced expression of ISG20, and RIG-I may mediate ISG20 expression induced by poly (I:C)/cationic lipid complex. Poly I-C 150-160 interferon stimulated exonuclease gene 20 Homo sapiens 122-127 20564542-10 2010 Phytohemagglutinine (PHA)-stimulated PBMC from patients with hyaluronic implants presenting adverse effects showed a slight increase in the production of interferon (IFN)-gamma and higher expression of CD25, CD69, or CD71. phytohemagglutinine 0-19 interferon stimulated exonuclease gene 20 Homo sapiens 202-206 20564542-10 2010 Phytohemagglutinine (PHA)-stimulated PBMC from patients with hyaluronic implants presenting adverse effects showed a slight increase in the production of interferon (IFN)-gamma and higher expression of CD25, CD69, or CD71. 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-hexanoylamine 21-24 interferon stimulated exonuclease gene 20 Homo sapiens 202-206 20564542-10 2010 Phytohemagglutinine (PHA)-stimulated PBMC from patients with hyaluronic implants presenting adverse effects showed a slight increase in the production of interferon (IFN)-gamma and higher expression of CD25, CD69, or CD71. hyaluronic 61-71 interferon stimulated exonuclease gene 20 Homo sapiens 202-206 20394727-0 2010 Uptake of donor lymphocytes treated with 8-methoxypsoralen and ultraviolet A light by recipient dendritic cells induces CD4+CD25+Foxp3+ regulatory T cells and down-regulates cardiac allograft rejection. Methoxsalen 41-58 interferon stimulated exonuclease gene 20 Homo sapiens 124-128 15794856-4 2005 However, there were differences in the k/l ratio (1.2:1 for SMZL and 4.5:1 for WM) and in some markers such as CD22 and CD11c, which were overexpressed in patients with SMZL compared with patients with WM, whereas CD25 was more frequently positive in WM (88% vs. 44%). smzl 169-173 interferon stimulated exonuclease gene 20 Homo sapiens 214-218 20629311-4 2010 The effects of CD4+ CD25high CCR6+ regulatory T cells on the proliferation of CD4+ CD25- T cells also were detected by 3H-incorporation assay. Tritium 119-121 interferon stimulated exonuclease gene 20 Homo sapiens 20-24 20629311-4 2010 The effects of CD4+ CD25high CCR6+ regulatory T cells on the proliferation of CD4+ CD25- T cells also were detected by 3H-incorporation assay. Tritium 119-121 interferon stimulated exonuclease gene 20 Homo sapiens 83-87 18448146-6 2008 As assessed by immunostaining, neoplastic MC were found to exhibit CD117 and CD25 but did not display CD5 or CD20, whereas SLL cells were found to coexpress CD5 and CD20 but did not express MC antigens. Methylcholanthrene 42-44 interferon stimulated exonuclease gene 20 Homo sapiens 77-81 18352910-3 2008 Poly IC-induced ISG20 expression was inhibited by LY294002, an inhibitor of PI3K, or by RNA interference against IFN regulatory factor three. Poly I-C 0-7 interferon stimulated exonuclease gene 20 Homo sapiens 16-21 18352910-3 2008 Poly IC-induced ISG20 expression was inhibited by LY294002, an inhibitor of PI3K, or by RNA interference against IFN regulatory factor three. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 50-58 interferon stimulated exonuclease gene 20 Homo sapiens 16-21 17045846-6 2007 CII (250-270) was found to have stimulated the response of specific lymphocytes in PBMC from RA patients, including the increase expression of surface activation antigen marker CD69 and CD25, and DNA synthesis. N-[(1S)-2-methyl-1-(pyridin-4-ylcarbamoyl)propyl]cyclohexanecarboxamide 0-3 interferon stimulated exonuclease gene 20 Homo sapiens 186-190 20394727-9 2010 Infusion of PUVA-SP DCs inhibited cardiac allograft rejection in an antigen-specific manner and induced CD4(+)CD25(high)Foxp3(+) regulatory T cells. puva-sp 12-19 interferon stimulated exonuclease gene 20 Homo sapiens 110-114 19890093-3 2010 CD25 was expressed on 83% of carboxyfluorescein diacetate succinimidyl ester(dim) ATs, confirming this as an excellent target for allodepletion. 5-(6)-carboxyfluorescein diacetate succinimidyl ester 29-76 interferon stimulated exonuclease gene 20 Homo sapiens 0-4 19146957-10 2009 The different effects of ASA on CD4(+)CD25(+)Foxp3(+) Treg cells and CD4(+)CD25(-) T cells may potentially make hosts susceptible to tolerance induction which would be beneficial for tolerance induction in patients with autoimmune diseases or allo-grafts. Aspirin 25-28 interferon stimulated exonuclease gene 20 Homo sapiens 38-42 17333724-7 2006 PBMCs cultured with artesunate or DHART simultaneously with PHA showed modestly reduced proportions of CD4+ and CD8+ T cells expressing CD69 and CD25. Artesunate 20-30 interferon stimulated exonuclease gene 20 Homo sapiens 145-149 17333724-7 2006 PBMCs cultured with artesunate or DHART simultaneously with PHA showed modestly reduced proportions of CD4+ and CD8+ T cells expressing CD69 and CD25. dhart 34-39 interferon stimulated exonuclease gene 20 Homo sapiens 145-149 16146851-5 2005 Results of flow cytometric analysis indicated that PEGG down-regulated the expression of CD25 and CD69 on T-cells stimulated by PHA. pegg 51-55 interferon stimulated exonuclease gene 20 Homo sapiens 89-93 12613520-0 2002 Are activation markers (CD25, CD38 and CD103) predictive of sensitivity to purine analogues in patients with T-cell prolymphocytic leukemia and other lymphoproliferative disorders? purine 75-81 interferon stimulated exonuclease gene 20 Homo sapiens 24-28 15295093-8 2004 In acidic oligosaccharide cultures, CD25+ expression on CD3+CD4+ cells was significantly elevated (p < 0.05). Oligosaccharides 10-25 interferon stimulated exonuclease gene 20 Homo sapiens 36-40 15527770-3 2004 We have solved the crystal structure of human ISG20 complexed with two Mn2+ ions and uridine 5"-monophosphate (UMP) at 1.9 A resolution. Manganese(2+) 71-75 interferon stimulated exonuclease gene 20 Homo sapiens 46-51 15527770-3 2004 We have solved the crystal structure of human ISG20 complexed with two Mn2+ ions and uridine 5"-monophosphate (UMP) at 1.9 A resolution. Uridine Monophosphate 85-109 interferon stimulated exonuclease gene 20 Homo sapiens 46-51 15527770-3 2004 We have solved the crystal structure of human ISG20 complexed with two Mn2+ ions and uridine 5"-monophosphate (UMP) at 1.9 A resolution. Uridine Monophosphate 111-114 interferon stimulated exonuclease gene 20 Homo sapiens 46-51 15527770-5 2004 However, ISG20 also has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2"-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates. Hydrogen 78-86 interferon stimulated exonuclease gene 20 Homo sapiens 9-14 15527770-5 2004 However, ISG20 also has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2"-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates. Hydrogen 78-86 interferon stimulated exonuclease gene 20 Homo sapiens 193-198 15527770-5 2004 However, ISG20 also has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2"-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates. Ribose 125-131 interferon stimulated exonuclease gene 20 Homo sapiens 9-14 15527770-5 2004 However, ISG20 also has distinctive residues, Met14 and Arg53, to accommodate hydrogen bonds with the 2"-OH group of the UMP ribose, and these residues may be responsible for the preference of ISG20 for RNA substrates. Ribose 125-131 interferon stimulated exonuclease gene 20 Homo sapiens 193-198 15064705-7 2004 As pIpC often induces protein movements in the cells, we questioned whether it could influence ISG20 localization. Piperacillin 3-7 interferon stimulated exonuclease gene 20 Homo sapiens 95-100 15101704-16 2004 Recently anti-CD22 and anti-CD25 immunotoxins have been investigated in purine analogues refractory or relapsed HCL. purine 72-78 interferon stimulated exonuclease gene 20 Homo sapiens 28-32 12423309-6 2002 The GSH(low) subset was characterized by enhanced numbers of CD4+ cells, reduced numbers of activated cells as characterized by CD25 and CD69, and reduced numbers of memory (CD45RO+) cells relative to the GSH(high) population. Glutathione 4-7 interferon stimulated exonuclease gene 20 Homo sapiens 128-132 10481384-16 1997 High CD4+CD25+ cell percentage was the most characteristic sign of lymphocyte activation in individuals exposed to silica. Silicon Dioxide 115-121 interferon stimulated exonuclease gene 20 Homo sapiens 9-13 11879282-6 2001 Since that time an anti-CD25 monoclonal antibody (dacliximab) and an anti-CD25 immunotoxin fusion product (denileukin diftitox) have become clinically available. diftitox 118-126 interferon stimulated exonuclease gene 20 Homo sapiens 74-78 11004845-7 2000 In individuals with chronic silica exposure we found: significant increase in alveolar macrophage (362 +/- 45 vs 160 +/- 33 x 10(3) cells/ml, p < 0.05), lymphocyte (61 +/- 9 vs 24 +/- 5 x 10(3) cells/ml, p < 0.05) and BAL total cell (415 +/- 76 vs 187 +/- 34 x 10(3) cells/ml, p < 0.05) numbers; significant increase in mast cell (0.4 +/- 0.1 vs 0.2 +/- 0.1, p < 0.05), NK cell (7.0 +/- 1.8 vs 3.6 +/- 1.0, p < 0.05) and Th early activated lymphocyte percent (CD4 + CD25+ calculated as percentage of CD4+ cells: 15.1 +/- 1.5 vs 7.8 +/- 1.6, p < 0.01). Silicon Dioxide 28-34 interferon stimulated exonuclease gene 20 Homo sapiens 481-485 9569007-10 1998 HEM45 mRNA expression in cultured cells was increased by estrogen in the presence of cycloheximide, indicating direct ER-regulation of HEM45. Cycloheximide 85-98 interferon stimulated exonuclease gene 20 Homo sapiens 0-5 9569007-10 1998 HEM45 mRNA expression in cultured cells was increased by estrogen in the presence of cycloheximide, indicating direct ER-regulation of HEM45. Cycloheximide 85-98 interferon stimulated exonuclease gene 20 Homo sapiens 135-140 8552199-4 1995 TPA treatment induced hairy cell leukemia (HCL) characteristics, given by the membrane CD22 and CD25 expression and TRAP positivity in the majority of the cases tested. Tetradecanoylphorbol Acetate 0-3 interferon stimulated exonuclease gene 20 Homo sapiens 96-100 1705874-5 1991 Cytofluorometric analysis revealed a significant increase in the fractions of CD8 cells and CD16/56 cells expressing CD25 for the Prol + group, compared to the Prol- and control groups. prol + 130-136 interferon stimulated exonuclease gene 20 Homo sapiens 117-121 1705874-5 1991 Cytofluorometric analysis revealed a significant increase in the fractions of CD8 cells and CD16/56 cells expressing CD25 for the Prol + group, compared to the Prol- and control groups. L-Pro 130-134 interferon stimulated exonuclease gene 20 Homo sapiens 117-121 1705874-6 1991 Similarly, the fractions of CD25 cells expressing CD8 or CD16/56 were significantly increased in the Prol + group. prol + 101-107 interferon stimulated exonuclease gene 20 Homo sapiens 28-32 2194392-7 1990 When stimulated in vitro by anti-mu and TPA, (phorbol ester) tumor cells showed a decrease in CD21 and Slg and a stronger expression of CD25, T9, T10, and PCA1, with evidence of Ig secretion in four out of the seven cases studied. Tetradecanoylphorbol Acetate 40-43 interferon stimulated exonuclease gene 20 Homo sapiens 136-140 2194392-7 1990 When stimulated in vitro by anti-mu and TPA, (phorbol ester) tumor cells showed a decrease in CD21 and Slg and a stronger expression of CD25, T9, T10, and PCA1, with evidence of Ig secretion in four out of the seven cases studied. Phorbol Esters 46-59 interferon stimulated exonuclease gene 20 Homo sapiens 136-140 7032747-6 1982 The dose of isoproterenol required to increase the heart rate by 25 beats/min (CD25) was also greater in the high than in the low blood pressure group (1.9 +/- 0.5 micrograms vs 0.9 +/- 0.2 micrograms, p less than 0.05). Isoproterenol 12-25 interferon stimulated exonuclease gene 20 Homo sapiens 79-83 34769072-0 2021 Establishment of a Rapid Detection System for ISG20-Dependent SARS-CoV-2 Subreplicon RNA Degradation Induced by Interferon-alpha. -alpha 122-128 interferon stimulated exonuclease gene 20 Homo sapiens 46-51 34233193-5 2021 The in vitro cytotoxic effect of tumor CD8 T cells is inhibited by CD4+CD25+ cells, and this suppressive effect is blocked by ADWA-11. adwa-11 126-133 interferon stimulated exonuclease gene 20 Homo sapiens 71-75 34145401-6 2022 In addition, a significant increase in the percentage of CD4+CD25+highFoxp3+ Tregs was found in untreated SCD patients, compared to in HU-treated patients and controls. Hydroxyurea 135-137 interferon stimulated exonuclease gene 20 Homo sapiens 61-65 33969602-0 2021 Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20. cccdna 67-73 interferon stimulated exonuclease gene 20 Homo sapiens 90-95 33949684-4 2021 In this study, we developed a GMP-compatible protocol for expanding sorted thymus derived CD3+ CD4+ CD25+ CD127- (Tregs) as well as CD3+ CD4+ CD25+ CD127- CD45RA+ (RA+ Tregs) cells. guanosine 5'-monophosphorothioate 30-33 interferon stimulated exonuclease gene 20 Homo sapiens 100-104 33949684-8 2021 After freezing and thawing all Treg preparations maintained their suppressive ability, stability as well as CD25 and FOXP3 expression. treg 31-35 interferon stimulated exonuclease gene 20 Homo sapiens 108-112 33969602-5 2021 ISG20 localizes to nucleoli of interferon-stimulated hepatocytes and is enriched on deoxyuridine-containing single-stranded DNA that mimics transcriptionally active, APOBEC3A-deaminated HBV DNA. Deoxyuridine 84-96 interferon stimulated exonuclease gene 20 Homo sapiens 0-5 33830434-4 2021 Further, ISG20 expression was upregulated following PRV infection and poly(I:C) treatment. Poly I-C 70-79 interferon stimulated exonuclease gene 20 Homo sapiens 9-14 33887579-4 2021 Among them, 11 KTx recipients showed dnDSA formation, which was associated with lower frequencies of CD25highCD127-CD4+ Treg cells (P = .040). dndsa 37-42 interferon stimulated exonuclease gene 20 Homo sapiens 101-105 32383789-6 2020 Furthermore, DTFL showed significantly fewer circulating FOXP3hi CD45RA- CD25hi eTregs (0 146%) than ASFL (0 497%) and healthy controls (0 639%) (P = 0 0003, P = 6 79 x 10-7 , respectively). dtfl 13-17 interferon stimulated exonuclease gene 20 Homo sapiens 73-77 33274645-0 2021 Dioscin alleviates hashimoto"s thyroiditis by regulating the SUMOylation of IRF4 to promote CD4+CD25+Foxp3+ treg cell differentiation. dioscin 0-7 interferon stimulated exonuclease gene 20 Homo sapiens 96-100 33274645-11 2021 The results of our study indicate that dioscin can promote the differentiation of the CD4+CD25+Foxp3+ Treg cells and subsequently upregulate the SUMOylation of IRF4 by downregulating SENP1 expression. dioscin 39-46 interferon stimulated exonuclease gene 20 Homo sapiens 90-94 32578199-7 2020 Educated CD25+CD127- regulatory T-cells (edu.Tregs) were more effective at preventing CD4 T-cell alloresponses to endothelial cells compared with naive Treg; anti-A/B antibodies were not involved in the Treg-mediated events. tregs 45-50 interferon stimulated exonuclease gene 20 Homo sapiens 9-13 32578199-7 2020 Educated CD25+CD127- regulatory T-cells (edu.Tregs) were more effective at preventing CD4 T-cell alloresponses to endothelial cells compared with naive Treg; anti-A/B antibodies were not involved in the Treg-mediated events. treg 45-49 interferon stimulated exonuclease gene 20 Homo sapiens 9-13 32578199-7 2020 Educated CD25+CD127- regulatory T-cells (edu.Tregs) were more effective at preventing CD4 T-cell alloresponses to endothelial cells compared with naive Treg; anti-A/B antibodies were not involved in the Treg-mediated events. treg 152-156 interferon stimulated exonuclease gene 20 Homo sapiens 9-13 32383789-6 2020 Furthermore, DTFL showed significantly fewer circulating FOXP3hi CD45RA- CD25hi eTregs (0 146%) than ASFL (0 497%) and healthy controls (0 639%) (P = 0 0003, P = 6 79 x 10-7 , respectively). etregs 80-86 interferon stimulated exonuclease gene 20 Homo sapiens 73-77 32059034-0 2020 Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts. N-methyladenosine 59-77 interferon stimulated exonuclease gene 20 Homo sapiens 31-36 33101284-5 2020 The suppressive function of Tregs on CD4+CD25- T cells was compared in preterm, term and adult blood. tregs 28-33 interferon stimulated exonuclease gene 20 Homo sapiens 41-45 32059034-3 2020 Here, we show that the N6-methyladenosine (m6A)-modified HBV transcripts are selectively recognized and processed for degradation by ISG20. N-methyladenosine 43-46 interferon stimulated exonuclease gene 20 Homo sapiens 133-138 32842201-0 2020 [The role of budesonide on CD8+CD25+Foxp3+ Treg cells in neutrophilic nasal polyps]. Budesonide 13-23 interferon stimulated exonuclease gene 20 Homo sapiens 31-35 32059034-3 2020 Here, we show that the N6-methyladenosine (m6A)-modified HBV transcripts are selectively recognized and processed for degradation by ISG20. N-methyladenosine 23-41 interferon stimulated exonuclease gene 20 Homo sapiens 133-138 28040549-7 2017 Unlike IFN-free regimens, SOF plus IFN/ribavirin induced a transiently increased frequency of Foxp3+ CD25+ CD4+ T cells at EOT (5.0% at baseline to 6.1% at EOT; p=0.001). Ribavirin 39-48 interferon stimulated exonuclease gene 20 Homo sapiens 101-105 31068044-3 2019 HCLv, lacking CD25, Anxa1, TRAP, and BRAF V600E, is more aggressive and less purine analog-sensitive. hclv 0-4 interferon stimulated exonuclease gene 20 Homo sapiens 14-18 30293884-7 2019 At week 24, peripheral blood CD4+CD25+high T cells with tacrolimus decreased significantly (P<0.01), but increased significantly without tacrolimus (P<0.01). Tacrolimus 56-66 interferon stimulated exonuclease gene 20 Homo sapiens 33-37 30375272-2 2019 Aim: To investigate the association between neonatal 25-hydroxy vitamin D (25-OHD) level and the expression of lymphocyte activation markers (HLA-DR, CD69, CD25, CD45RA) on T-lymphocyte subpopulations and its impact in neonatal infection. 25-hydroxyvitamin D 53-73 interferon stimulated exonuclease gene 20 Homo sapiens 156-160 29963243-8 2018 Importantly, ISG20 levels were strongly correlated with the levels of AST, ALT, total and direct bilirubin among HCC patients (Pearson"s r = 0.43, 0.35, 0.34, 0.3; P<0.0001, respectively). Bilirubin 97-106 interferon stimulated exonuclease gene 20 Homo sapiens 13-18 28040549-9 2017 CONCLUSION: Although IFN-based DAA therapy induced transient expansion of activated Foxp3+ CD25+ CD4+ T cells, neither IFN-based nor IFN-free DAA regimens normalized frequencies and activation status of Tregs one year after viral elimination. daa 31-34 interferon stimulated exonuclease gene 20 Homo sapiens 91-95 28118317-0 2017 CD45RA Distinguishes CD4+CD25+CD127-/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression. Tacrolimus 142-152 interferon stimulated exonuclease gene 20 Homo sapiens 25-29 26438270-0 2015 Up-regulated S100 calcium binding protein A8 in Plasmodium-infected patients correlates with CD4(+)CD25(+)Foxp3 regulatory T cell generation. Calcium 18-25 interferon stimulated exonuclease gene 20 Homo sapiens 99-103 27150987-6 2016 Compared with CD25(-) AML patients, CD25(+) AML patients had lower CR rate (the CR rate of 1 course of treatment were 49.02% and 16.00%, respectively, P < 0.05, the CR rate of 2 courses of treatment were 74.60% and 46.67%, respectively, P < 0.05), and the OS time of CD25(+) AML patients were obviously shorter (P < 0.05). Chromium 67-69 interferon stimulated exonuclease gene 20 Homo sapiens 36-40 27150987-6 2016 Compared with CD25(-) AML patients, CD25(+) AML patients had lower CR rate (the CR rate of 1 course of treatment were 49.02% and 16.00%, respectively, P < 0.05, the CR rate of 2 courses of treatment were 74.60% and 46.67%, respectively, P < 0.05), and the OS time of CD25(+) AML patients were obviously shorter (P < 0.05). Chromium 67-69 interferon stimulated exonuclease gene 20 Homo sapiens 36-40 25563193-7 2015 Additionally, intratumoral Treg showed a higher inhibitory function on autologous CD4(+)CD25(-) T cells when compared with circulating Treg that may be explained by an overexpression of FoxP3 transcription factor. treg 27-31 interferon stimulated exonuclease gene 20 Homo sapiens 88-92 24237448-7 2014 Lenalidomide impaired long-term thymic T-cell reconstitution, decreased CD4 + and CD8 + CD45RA + CCR7 - effector-terminal T-cell absolute counts and increased CD4 + CD25 + CD127 - /low regulatory T-cells. Lenalidomide 0-12 interferon stimulated exonuclease gene 20 Homo sapiens 165-169