PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
291565-4	1979	Resistance to erythromycin has been mapped on the chromosomes of two S. coelicolor A3(2) derivatives in different sites: between markers adeC (v 10) and ArgA1 in the strain A617, between pheA1 and SCP1 in the strain S18.	Erythromycin	14-26	synaptonemal complex protein 1	Homo sapiens	197-201
35377450-4	2022	This single nucleotide deletion not only changes lysine 967 (K) into asparagine (N) but also causes a premature stop codon, which leads to deletion of 968-976 residues from the end of the C-tail region of the SYCP1 protein.	Asparagine	69-79	synaptonemal complex protein 1	Homo sapiens	209-214
822125-1	1976	The antibiotic whose biosynthesis is determined by the SCP1 plasmid of Streptomyces coelicolor A3(2) has been characterized as the recently described methylenomycin A (2-methylene-cyclopentan-3-one-4,5-epoxy-4,5-dimethyl-1-carboxylic acid).	Methylenomycin A	150-166	synaptonemal complex protein 1	Homo sapiens	55-59
833570-0	1977	Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2).	methylenomycin A	25-39	synaptonemal complex protein 1	Homo sapiens	57-61
833570-1	1977	Evidence is presented that genes determining the pathway of methylenomycin A synthesis are carried on the SCP1 plasmid.	methylenomycin A	60-76	synaptonemal complex protein 1	Homo sapiens	106-110
822125-1	1976	The antibiotic whose biosynthesis is determined by the SCP1 plasmid of Streptomyces coelicolor A3(2) has been characterized as the recently described methylenomycin A (2-methylene-cyclopentan-3-one-4,5-epoxy-4,5-dimethyl-1-carboxylic acid).	2-methylene-cyclopentan-3-one-4,5-epoxy-4,5-dimethyl-1-carboxylic acid	168-238	synaptonemal complex protein 1	Homo sapiens	55-59
33639236-4	2021	We thus investigated differentiating hMSCs and the mesenchymal stem cell line SCP-1 cultured under osteogenic conditions and stimulated with supra-physiological cortisone levels.	Cortisone	161-170	synaptonemal complex protein 1	Homo sapiens	78-83
30327145-0	2018	Synthesis, hepatotoxic evaluation and antipyretic activity of nitrate ester analogs of the acetaminophen derivative SCP-1.	nitrate ester	62-75	synaptonemal complex protein 1	Homo sapiens	116-121
32568099-7	2020	CPs dramatically rescued the expression of important genes and proteins (STRA8, DAZL, SYCP1, SYCP3, TNP1 etc.)	cps	0-3	synaptonemal complex protein 1	Homo sapiens	86-91
30327145-0	2018	Synthesis, hepatotoxic evaluation and antipyretic activity of nitrate ester analogs of the acetaminophen derivative SCP-1.	Acetaminophen	91-104	synaptonemal complex protein 1	Homo sapiens	116-121
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	nitrate ester	12-25	synaptonemal complex protein 1	Homo sapiens	68-73
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	nitrate ester	12-25	synaptonemal complex protein 1	Homo sapiens	129-134
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	Acetaminophen	43-56	synaptonemal complex protein 1	Homo sapiens	68-73
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	Acetaminophen	43-56	synaptonemal complex protein 1	Homo sapiens	129-134
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	trifluoromethanesulfonic acid	91-103	synaptonemal complex protein 1	Homo sapiens	68-73
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	trifluoromethanesulfonic acid	91-103	synaptonemal complex protein 1	Homo sapiens	129-134
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	chloroalkanoyl chlorides	140-164	synaptonemal complex protein 1	Homo sapiens	68-73
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	chloroalkanoyl chlorides	140-164	synaptonemal complex protein 1	Homo sapiens	129-134
30327145-1	2018	A series of nitrate ester analogues of the acetaminophen derivative SCP-1 were prepared by triflic acid catalyzed O-acylation of SCP-1 with chloroalkanoyl chlorides followed by nitration with silver nitrate.	Silver Nitrate	192-206	synaptonemal complex protein 1	Homo sapiens	68-73
27751849-0	2016	27-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells.	27-hydroxycholesterol	0-21	synaptonemal complex protein 1	Homo sapiens	76-80
30533170-0	2018	Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke.	Nicotine	0-8	synaptonemal complex protein 1	Homo sapiens	119-124
30533170-0	2018	Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke.	Cotinine	13-21	synaptonemal complex protein 1	Homo sapiens	119-124
29264620-7	2018	As a treatment strategy, co-incubation of the CSE-exposed SCP-1 cells with the antioxidant resveratrol (1 microM) had a protective effect as it significantly reduced free radical production, protected the primary cilia and enhanced osteogenic differentiation.	Resveratrol	91-102	synaptonemal complex protein 1	Homo sapiens	58-63
29264620-7	2018	As a treatment strategy, co-incubation of the CSE-exposed SCP-1 cells with the antioxidant resveratrol (1 microM) had a protective effect as it significantly reduced free radical production, protected the primary cilia and enhanced osteogenic differentiation.	Free Radicals	166-178	synaptonemal complex protein 1	Homo sapiens	58-63
29521042-10	2018	Additional application of dexamethasone to SCP-1 cells further increased the RANKL/OPG ratio 3-fold, but decreased IL-6 and IL-1beta expression to 10% and 50%, respectively.	Dexamethasone	26-39	synaptonemal complex protein 1	Homo sapiens	43-48
24491559-5	2014	Overexpression of miR-124a or CoCl2 treatment suppressed the expression of anti-neural proteins such as SCP1 and SOX9.	cobaltous chloride	30-35	synaptonemal complex protein 1	Homo sapiens	104-108
26323297-3	2015	In this study, the short form of the coiled-coil domain of SYCP1 was overexpressed in Escherichia coli with an engineered C-terminal His tag.	Histidine	133-136	synaptonemal complex protein 1	Homo sapiens	59-64
25124847-5	2015	The SCP 1 is diamagnetic and exhibits good catalytic and photo-catalytic activities for the degradation of methylene blue (MB).	Methylene Blue	107-121	synaptonemal complex protein 1	Homo sapiens	4-9
25124847-5	2015	The SCP 1 is diamagnetic and exhibits good catalytic and photo-catalytic activities for the degradation of methylene blue (MB).	Methylene Blue	123-125	synaptonemal complex protein 1	Homo sapiens	4-9
26642107-5	2015	High bound water content avoids the membrane dehydration, and most optimal (SCP-1.33) membrane exhibited about ~2.5-fold high bound water content in comparison with that of Nafion117 membrane.	Water	11-16	synaptonemal complex protein 1	Homo sapiens	76-81
26642107-5	2015	High bound water content avoids the membrane dehydration, and most optimal (SCP-1.33) membrane exhibited about ~2.5-fold high bound water content in comparison with that of Nafion117 membrane.	Water	132-137	synaptonemal complex protein 1	Homo sapiens	76-81
26642107-5	2015	High bound water content avoids the membrane dehydration, and most optimal (SCP-1.33) membrane exhibited about ~2.5-fold high bound water content in comparison with that of Nafion117 membrane.	nafion117	173-182	synaptonemal complex protein 1	Homo sapiens	76-81
26642107-7	2015	High current efficiency (83-99%) confirmed absence of any side reaction and 328.05 kJ mol-H2(-1) energy was required for to produce 1 mol of H2 by electrolytic cell with SCP-1.33 membrane.	Hydrogen	90-92	synaptonemal complex protein 1	Homo sapiens	170-175
24491559-6	2014	Silencing of both SCP1 and SOX9 induced neuronal differentiation of hMSCs, indicating that suppression of miR-124a targets is important for CoCl2-induced neuronal differentiation of hMSCs.	cobaltous chloride	140-145	synaptonemal complex protein 1	Homo sapiens	18-22
24491559-7	2014	Knockdown of HIF-1alpha or inhibition of JNK restored the expression of SCP1 and SOX9 in CoCl2-treated cells.	cobaltous chloride	89-94	synaptonemal complex protein 1	Homo sapiens	72-76
24491559-8	2014	Inhibition of miR-124a blocked CoCl2-induced suppression of SCP1 and SOX9 and abolished CoCl2-induced neuronal differentiation of hMSCs.	cobaltous chloride	31-36	synaptonemal complex protein 1	Homo sapiens	60-64
16432832-8	2006	The humoral immune response against SCP-1 was associated with the size of tumor, but not with other clinico-pathological parameters such as histology, stage, presence of lymph node metastases, grading, age, gender or gemcitabine treatment.	gemcitabine	217-228	synaptonemal complex protein 1	Homo sapiens	36-41
22446773-2	2012	The catalytic behavior of the SCP 1 was utilized for Fenton and photo-Fenton degradation of methylene blue dye (MB).	Methylene Blue	92-106	synaptonemal complex protein 1	Homo sapiens	30-35
22446773-2	2012	The catalytic behavior of the SCP 1 was utilized for Fenton and photo-Fenton degradation of methylene blue dye (MB).	mb	112-114	synaptonemal complex protein 1	Homo sapiens	30-35
24491559-9	2014	Taken together, we demonstrate that miR-124a is critically regulates CoCl2-induced neuronal differentiation of hMSCs by suppressing the expression of SCP1 and SOX9.	cobaltous chloride	69-74	synaptonemal complex protein 1	Homo sapiens	150-154
21920637-6	2011	The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to determine the in vitro antitumor effects of the SCP 1 on human breast cancer cell line, T-47D.	thiazolyl blue	4-64	synaptonemal complex protein 1	Homo sapiens	137-142
17595166-1	2007	In fission yeast, orthologs of mammalian SREBP and Scap, called Sre1 and Scp1, monitor oxygen-dependent sterol synthesis as a measure of cellular oxygen supply.	Oxygen	87-93	synaptonemal complex protein 1	Homo sapiens	73-77
17595166-1	2007	In fission yeast, orthologs of mammalian SREBP and Scap, called Sre1 and Scp1, monitor oxygen-dependent sterol synthesis as a measure of cellular oxygen supply.	Sterols	104-110	synaptonemal complex protein 1	Homo sapiens	73-77
17595166-1	2007	In fission yeast, orthologs of mammalian SREBP and Scap, called Sre1 and Scp1, monitor oxygen-dependent sterol synthesis as a measure of cellular oxygen supply.	Oxygen	146-152	synaptonemal complex protein 1	Homo sapiens	73-77
17595166-6	2007	Both increases and decreases in the level of these ergosterol pathway intermediates induce Sre1 proteolysis in a Scp1-dependent manner.	Ergosterol	51-61	synaptonemal complex protein 1	Homo sapiens	113-117
17595166-8	2007	Finally, we provide evidence that the sterol-sensing domain of Scp1 is important for regulating Sre1 proteolysis.	Sterols	38-44	synaptonemal complex protein 1	Homo sapiens	63-67
17595166-9	2007	The conserved mutations Y247C, L264F, and D392N in Scp1 that render Scap insensitive to sterols cause constitutive Sre1 activation.	Sterols	88-95	synaptonemal complex protein 1	Homo sapiens	51-55
17595166-10	2007	These findings indicate that unlike Scap, fission yeast Scp1 responds to 4-methyl sterols and thus shares properties with mammalian HMG-CoA reductase, a sterol-sensing domain protein whose degradation is regulated by the 4-methyl sterol lanosterol.	4-methyl sterols	73-89	synaptonemal complex protein 1	Homo sapiens	56-60
17595166-10	2007	These findings indicate that unlike Scap, fission yeast Scp1 responds to 4-methyl sterols and thus shares properties with mammalian HMG-CoA reductase, a sterol-sensing domain protein whose degradation is regulated by the 4-methyl sterol lanosterol.	4-methyl sterol lanosterol	221-247	synaptonemal complex protein 1	Homo sapiens	56-60
15487888-3	2004	We used immunohistochemistry (IHC) to investigate SCP-1 expression in paraffin-fixed EOC samples and ELISA to test sera from a subgroup of patients for SCP-1 antibody.	Paraffin	70-78	synaptonemal complex protein 1	Homo sapiens	50-55
15235794-6	2004	Leptotene and zygotene oocytes and spermatocytes showed strong gamma-H2AX labeling, while gamma-H2AX patches, which colocalized with RPA, were present on SYCP1-tagged pachytene SCs.	gamma-h2ax	90-100	synaptonemal complex protein 1	Homo sapiens	154-159