PMID-sentid	Pub_year	Sent_text	comp_official_name	comp_offset	protein_name	organism	prot_offset
2257996-0	1990	Myo-inositol and prostaglandins reverse the glucose inhibition of neural tube fusion in cultured mouse embryos.	Glucose	44-51	synaptopodin 2	Mus musculus	0-3
2257996-3	1990	The failure of rostral neural tube fusion seen in mouse embryos incubated in the presence of excess-D-glucose can be significantly prevented by the supplementation of myo-inositol to the culture medium.	Glucose	100-109	synaptopodin 2	Mus musculus	167-170
2257996-4	1990	This protective effect of myo-inositol is reversed by indomethacin, an inhibitor of arachidonic acid metabolism leading to prostaglandin synthesis.	Indomethacin	54-66	synaptopodin 2	Mus musculus	26-29
2257996-4	1990	This protective effect of myo-inositol is reversed by indomethacin, an inhibitor of arachidonic acid metabolism leading to prostaglandin synthesis.	Arachidonic Acid	84-100	synaptopodin 2	Mus musculus	26-29
2257996-4	1990	This protective effect of myo-inositol is reversed by indomethacin, an inhibitor of arachidonic acid metabolism leading to prostaglandin synthesis.	Prostaglandins	123-136	synaptopodin 2	Mus musculus	26-29
2257996-6	1990	These data suggest that the failure of neural tube fusion seen in diabetic embryopathy is mediated through a mechanism involving abnormalities in both the myo-inositol and arachidonic acid pathways, resulting in a functional deficiency of prostaglandins at a critical time of neural tube fusion.	Prostaglandins	239-253	synaptopodin 2	Mus musculus	155-158
35328671-0	2022	Description of Osmolyte Pathways in Maturing Mdx Mice Reveals Altered Levels of Taurine and Sodium/Myo-Inositol Co-Transporters.	Sodium	92-98	synaptopodin 2	Mus musculus	99-102
6497780-0	1984	The contribution of inositol exchange to agonist-stimulated breakdown of myo- [2-3H] inositol-labelled phosphatidylinositol in mouse exocrine pancreas.	Inositol	20-28	synaptopodin 2	Mus musculus	73-76
6497780-0	1984	The contribution of inositol exchange to agonist-stimulated breakdown of myo- [2-3H] inositol-labelled phosphatidylinositol in mouse exocrine pancreas.	Phosphatidylinositols	103-123	synaptopodin 2	Mus musculus	73-76
6497780-1	1984	Agonists stimulate the release of myo-inositol from phosphatidylinositol (PtdIns) labelled in vivo with myo-[2-3H] inositol.	Phosphatidylinositols	52-72	synaptopodin 2	Mus musculus	34-37
6497780-1	1984	Agonists stimulate the release of myo-inositol from phosphatidylinositol (PtdIns) labelled in vivo with myo-[2-3H] inositol.	Phosphatidylinositols	52-72	synaptopodin 2	Mus musculus	104-107
6497780-1	1984	Agonists stimulate the release of myo-inositol from phosphatidylinositol (PtdIns) labelled in vivo with myo-[2-3H] inositol.	Phosphatidylinositols	74-80	synaptopodin 2	Mus musculus	34-37
6497780-1	1984	Agonists stimulate the release of myo-inositol from phosphatidylinositol (PtdIns) labelled in vivo with myo-[2-3H] inositol.	Phosphatidylinositols	74-80	synaptopodin 2	Mus musculus	104-107
6497780-2	1984	In the presence of lithium, which inhibits myo-inositol-1-phosphatase, the compound which accumulates following the breakdown of pre-labelled PtdIns is inositol-1-phosphate.	Lithium	19-26	synaptopodin 2	Mus musculus	43-46
6497780-2	1984	In the presence of lithium, which inhibits myo-inositol-1-phosphatase, the compound which accumulates following the breakdown of pre-labelled PtdIns is inositol-1-phosphate.	Phosphatidylinositols	142-148	synaptopodin 2	Mus musculus	43-46
6497780-2	1984	In the presence of lithium, which inhibits myo-inositol-1-phosphatase, the compound which accumulates following the breakdown of pre-labelled PtdIns is inositol-1-phosphate.	inositol 1-phosphate	152-172	synaptopodin 2	Mus musculus	43-46
6497780-5	1984	Agonist-induced release of myo-[2-3H] inositol can be used as a reliable indication of PtdIns breakdown in the exocrine pancreas.	Phosphatidylinositols	87-93	synaptopodin 2	Mus musculus	27-30
31376937-4	2019	Myo-inositol is an abundant carbohydrate in the environment and in certain organs of the human body, especially the brain.	Carbohydrates	28-40	synaptopodin 2	Mus musculus	0-3
33209742-9	2020	For both 4 and 8 hr preincubation times, myo-inositole could decrease H2O2 and increase GSH and MMP levels and consequently could improve fertilization rate compared to oocytes preincubated in the simple culture.	Hydrogen Peroxide	70-74	synaptopodin 2	Mus musculus	41-44
33209742-9	2020	For both 4 and 8 hr preincubation times, myo-inositole could decrease H2O2 and increase GSH and MMP levels and consequently could improve fertilization rate compared to oocytes preincubated in the simple culture.	Glutathione	88-91	synaptopodin 2	Mus musculus	41-44
33716965-0	2021	The Association of Myo-Inositol and Selenium Contrasts Cadmium-Induced Thyroid C Cell Hyperplasia and Hypertrophy in Mice.	Selenium	36-44	synaptopodin 2	Mus musculus	19-22
33716965-0	2021	The Association of Myo-Inositol and Selenium Contrasts Cadmium-Induced Thyroid C Cell Hyperplasia and Hypertrophy in Mice.	Cadmium	55-62	synaptopodin 2	Mus musculus	19-22
33716965-15	2021	In conclusion, the association Myo + Se is effective in protecting the mouse thyroid from the Cd-induced hyperplasia and hypertrophy of C cells.	Selenomethionine	37-39	synaptopodin 2	Mus musculus	31-34
33716965-15	2021	In conclusion, the association Myo + Se is effective in protecting the mouse thyroid from the Cd-induced hyperplasia and hypertrophy of C cells.	Cadmium	94-96	synaptopodin 2	Mus musculus	31-34
32590101-5	2020	Inositols were administered as mixture of myo-inositol and D-chiro-inositol in the drinking water.	Inositol	0-9	synaptopodin 2	Mus musculus	42-45
31376937-10	2019	Taken together, our findings suggest that using the Ino-cluster products, C. koseri can exploit the abundant myo-inositol in the brain as a carbon source for growth, thus promoting colonization and virulence.	Carbon	140-146	synaptopodin 2	Mus musculus	109-112
16511884-5	2006	It was recently suggested that a relationship exists between VPA exposure and the cellular depletion of myo-inositol (INO).	Inositol	118-121	synaptopodin 2	Mus musculus	104-107
30357747-1	2018	Myo-inositol is a highly abundant stereoisomer of the inositol family of sugar alcohols and forms the structural basis for a variety of polyphosphate derivatives including second messengers and membrane phospholipids.	Inositol	4-12	synaptopodin 2	Mus musculus	0-3
30357747-1	2018	Myo-inositol is a highly abundant stereoisomer of the inositol family of sugar alcohols and forms the structural basis for a variety of polyphosphate derivatives including second messengers and membrane phospholipids.	Sugar Alcohols	73-87	synaptopodin 2	Mus musculus	0-3
30357747-1	2018	Myo-inositol is a highly abundant stereoisomer of the inositol family of sugar alcohols and forms the structural basis for a variety of polyphosphate derivatives including second messengers and membrane phospholipids.	Polyphosphates	136-149	synaptopodin 2	Mus musculus	0-3
30357747-1	2018	Myo-inositol is a highly abundant stereoisomer of the inositol family of sugar alcohols and forms the structural basis for a variety of polyphosphate derivatives including second messengers and membrane phospholipids.	Phospholipids	203-216	synaptopodin 2	Mus musculus	0-3
30357747-3	2018	Myo-inositol can be formed endogenously from the breakdown of glucose, is found in a variety of foods including breastmilk and is commercially available as a nutritional supplement.	Glucose	62-69	synaptopodin 2	Mus musculus	0-3
16511884-0	2006	Myo-inositol enhances teratogenicity of valproic acid in the mouse.	Valproic Acid	40-53	synaptopodin 2	Mus musculus	0-3
30317628-5	2019	When mice were returned to a normal light-dark regimen for 10 days, a slight, spontaneous improvement occurred, whereas a quick and almost complete recovery from PCOS signs and symptoms was obtained by treating animals with a daily supplementation of 420 mg/kg myo-inositol and D-chiro-inositol (MyoIns/DCIns) in a 40:1 molar ratio.	Inositol	278-294	synaptopodin 2	Mus musculus	261-264
30317628-5	2019	When mice were returned to a normal light-dark regimen for 10 days, a slight, spontaneous improvement occurred, whereas a quick and almost complete recovery from PCOS signs and symptoms was obtained by treating animals with a daily supplementation of 420 mg/kg myo-inositol and D-chiro-inositol (MyoIns/DCIns) in a 40:1 molar ratio.	myoins	296-302	synaptopodin 2	Mus musculus	261-264
30317628-5	2019	When mice were returned to a normal light-dark regimen for 10 days, a slight, spontaneous improvement occurred, whereas a quick and almost complete recovery from PCOS signs and symptoms was obtained by treating animals with a daily supplementation of 420 mg/kg myo-inositol and D-chiro-inositol (MyoIns/DCIns) in a 40:1 molar ratio.	dcins	303-308	synaptopodin 2	Mus musculus	261-264
28811707-4	2017	RESULTS: In mice, pbeta-cateninS552 staining faithfully reported the effects of myo-inositol in reducing inflammation and intestinal stem cell activation.	pbeta-catenins552	18-35	synaptopodin 2	Mus musculus	80-83
27489288-2	2016	Here, we determine whether inhibition of the hypoxic tumor response through myo-inositol trispyrophosphate (ITPP), a compound with antihypoxic properties, is able to cause prolonged vascular normalization that can be exploited to improve standard-of-care treatment.	inositol trispyrophosphate	108-112	synaptopodin 2	Mus musculus	76-79
16511884-5	2006	It was recently suggested that a relationship exists between VPA exposure and the cellular depletion of myo-inositol (INO).	Valproic Acid	61-64	synaptopodin 2	Mus musculus	104-107
11673475-10	2001	Myopodin has actin-bundling activity as shown by formation of latrunculin-A-sensitive cytosolic actin bundles and nuclear actin loops in transfected cells expressing green fluorescent protein-myopodin.	latrunculin A	62-75	synaptopodin 2	Mus musculus	0-8
15817640-6	2005	Conscious myo-/- mice evaluated by echocardiography display lowered cardiac output (0.64+/-0.06 vs. 0.75+/-0.09 ml x min(-1) x g(-1), myo-/- vs. WT, P<0.001), impaired systolic shortening (60+/-3.5 vs. 65+/-4%, myo-/- vs. WT, P<0.001) and fail to respond to beta1-stimulation.	beta1	264-269	synaptopodin 2	Mus musculus	10-13
12954456-0	2003	Myo-inositol restores the inflammation-induced down-regulation of taurine transport by the murine macrophage cell line, RAW 264.7.	Taurine	66-73	synaptopodin 2	Mus musculus	0-3
12954456-1	2003	The role of myo-inositol in the regulation of taurine transport in activated murine macrophage cell line, RAW 264.7, was studied.	Taurine	46-53	synaptopodin 2	Mus musculus	12-15
12954456-3	2003	Among the various monosaccharides (1 mM) tested in the presence of PMA, myo-inositol was most effective in restoring the PMA-induced down-regulation of taurine transport in murine macrophages (82% increase compared to the value for cells treated with PMA Alone, p < 0.01).	Monosaccharides	18-33	synaptopodin 2	Mus musculus	72-75
12954456-3	2003	Among the various monosaccharides (1 mM) tested in the presence of PMA, myo-inositol was most effective in restoring the PMA-induced down-regulation of taurine transport in murine macrophages (82% increase compared to the value for cells treated with PMA Alone, p < 0.01).	Tetradecanoylphorbol Acetate	67-70	synaptopodin 2	Mus musculus	72-75
12954456-3	2003	Among the various monosaccharides (1 mM) tested in the presence of PMA, myo-inositol was most effective in restoring the PMA-induced down-regulation of taurine transport in murine macrophages (82% increase compared to the value for cells treated with PMA Alone, p < 0.01).	Tetradecanoylphorbol Acetate	121-124	synaptopodin 2	Mus musculus	72-75
12954456-3	2003	Among the various monosaccharides (1 mM) tested in the presence of PMA, myo-inositol was most effective in restoring the PMA-induced down-regulation of taurine transport in murine macrophages (82% increase compared to the value for cells treated with PMA Alone, p < 0.01).	Tetradecanoylphorbol Acetate	121-124	synaptopodin 2	Mus musculus	72-75
12954456-4	2003	The protective role of myo-inositol against stress-induced down-regulation of taurine transport by macrophages was further investigated in conditions mimicking bacterial infection, inflammation, and immune-suppressed circumstances.	Taurine	78-85	synaptopodin 2	Mus musculus	23-26
12954456-8	2003	Again, this inflammation-induced down-regulation of taurine transport activity was completely antagonized with co-administration of 100 nM or higher levels of myo-inositol in the culture medium.	Taurine	52-59	synaptopodin 2	Mus musculus	159-162
12954456-9	2003	Similarly, myo-inositol effectively restored the taurine transport activity suppressed by cyclosporin A (0.5 and 50 nM) in murine macrophages (p < 0.01).	Taurine	49-56	synaptopodin 2	Mus musculus	11-14
12954456-9	2003	Similarly, myo-inositol effectively restored the taurine transport activity suppressed by cyclosporin A (0.5 and 50 nM) in murine macrophages (p < 0.01).	Cyclosporine	90-103	synaptopodin 2	Mus musculus	11-14
12954456-10	2003	From these results, myo-inositol appears to be a common accelerator of taurine transport by murine macrophages in diverse conditions of down-regulated taurine transport.	Taurine	71-78	synaptopodin 2	Mus musculus	20-23
12954456-10	2003	From these results, myo-inositol appears to be a common accelerator of taurine transport by murine macrophages in diverse conditions of down-regulated taurine transport.	Taurine	151-158	synaptopodin 2	Mus musculus	20-23
11673475-12	2001	Nuclear export of myopodin is sensitive to leptomycin B, despite the absence of a classical nuclear export sequence.	leptomycin B	43-55	synaptopodin 2	Mus musculus	18-26