PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9973225-13 1999 This was evidenced by the fact that chemotherapy agents that synergized with TRAIL (e.g., doxorubicin) themselves caused cleavage of caspase-3 and poly(ADP-ribose) polymerase (PARP), and their toxicity was blocked by the caspase inhibitor Z-Val-Ala-Asp(OMe)-CH2 (ZVAD-fmk). Doxorubicin 90-101 TNF superfamily member 10 Homo sapiens 77-82 9973225-9 1999 Incubation of cell lines with doxorubicin or 5-fluorouracil significantly augmented TRAIL-induced apoptosis in most breast cell lines. Doxorubicin 30-41 TNF superfamily member 10 Homo sapiens 84-89 9973225-12 1999 Augmentation of TRAIL-induced apoptosis by doxorubicin or 5-fluorouracil was mediated through caspase activation. Doxorubicin 43-54 TNF superfamily member 10 Homo sapiens 16-21