PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9920937-0 1999 Lysophosphatidic acid activates NF-kappaB in fibroblasts. lysophosphatidic acid 0-21 nuclear factor kappa B subunit 1 Homo sapiens 32-41 9920937-3 1999 In the present study, we investigated the possibility that LPA activates the transcription factor NF-kappaB. lysophosphatidic acid 59-62 nuclear factor kappa B subunit 1 Homo sapiens 98-107 9920937-5 1999 We find that LPA causes a marked activation of NF-kappaB in Swiss 3T3 fibroblasts as determined by the degradation of IkappaB-alpha in the cytosol and the emergence of kappaB binding activity in nuclear extracts. lysophosphatidic acid 13-16 nuclear factor kappa B subunit 1 Homo sapiens 47-56 9920937-11 1999 The data demonstrate the utilization of multiple pathways in the activation of NF-kappaB by LPA, not inconsistent with the relevance of several families of GTP-binding regulatory proteins. lysophosphatidic acid 92-95 nuclear factor kappa B subunit 1 Homo sapiens 79-88