PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9920651-4	1999	In vitro data demonstrate that NAMDA inhibited GTP cyclohydrolase I, the rate-limiting enzyme for BH4 biosynthesis, and reduced nitrite accumulation, an oxidative metabolite of NO, without directly inhibiting NOS activity.	N-acetyl-3-O-methyldopamine	31-36	GTP cyclohydrolase 1	Rattus norvegicus	47-67	
9920651-4	1999	In vitro data demonstrate that NAMDA inhibited GTP cyclohydrolase I, the rate-limiting enzyme for BH4 biosynthesis, and reduced nitrite accumulation, an oxidative metabolite of NO, without directly inhibiting NOS activity.	sapropterin	98-101	GTP cyclohydrolase 1	Rattus norvegicus	47-67	
9920651-5	1999	Animals exposed to transient forebrain ischemia and treated with NAMDA demonstrated marked reductions in ischemia-induced BH4 levels, NADPH-diaphorase activity, and caspase-3 gene expression in the CA1 hippocampus.	N-acetyl-3-O-methyldopamine	65-70	caspase 3	Rattus norvegicus	165-174	
9920651-5	1999	Animals exposed to transient forebrain ischemia and treated with NAMDA demonstrated marked reductions in ischemia-induced BH4 levels, NADPH-diaphorase activity, and caspase-3 gene expression in the CA1 hippocampus.	N-acetyl-3-O-methyldopamine	65-70	carbonic anhydrase 1	Rattus norvegicus	198-201	
9920651-5	1999	Animals exposed to transient forebrain ischemia and treated with NAMDA demonstrated marked reductions in ischemia-induced BH4 levels, NADPH-diaphorase activity, and caspase-3 gene expression in the CA1 hippocampus.	sapropterin	122-125	carbonic anhydrase 1	Rattus norvegicus	198-201	
9920651-6	1999	Moreover, delayed neuronal injury in the CA1 hippocampal region was significantly attenuated by NAMDA.	N-acetyl-3-O-methyldopamine	96-101	carbonic anhydrase 1	Rattus norvegicus	41-44