PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9889345-0 1999 Differential decreases in c-fos and aldolase C mRNA expression in the rat cerebellum after repeated administration of methamphetamine. Methamphetamine 118-133 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 26-31 9889345-2 1999 A single dose of methamphetamine induced c-fos mRNA expression in granule and Purkinje cells of both anterior and posterior lobes. Methamphetamine 17-32 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 41-46 9889345-4 1999 Repeated methamphetamine injections reduced methamphetamine-induced c-fos mRNA signals in the anterior hemisphere and in part of the posterior vermis (lobule VII) and posterior hemisphere. Methamphetamine 9-24 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 68-73 9889345-4 1999 Repeated methamphetamine injections reduced methamphetamine-induced c-fos mRNA signals in the anterior hemisphere and in part of the posterior vermis (lobule VII) and posterior hemisphere. Methamphetamine 44-59 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 68-73 9889345-5 1999 Aldolase C mRNA signals in Purkinje cells decreased only in lobules where methamphetamine-induced c-fos signals were not reduced (lobules VI and IX). Methamphetamine 74-89 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 98-103 9889345-6 1999 Therefore, differential decreases in c-fos mRNA and aldolase C mRNA expression after repeated methamphetamine administration depend upon the localization of Purkinje cells in the cerebellum. Methamphetamine 94-109 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 37-42 9889345-7 1999 Since c-fos mRNA and aldolase C mRNA expressions are markers of excitability and the metabolic state of Purkinje cells, respectively, hypofunction of inhibitory Purkinje cells could be induced if methamphetamine is repeatedly injected. Methamphetamine 196-211 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 6-11