PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9853756-3	1998	At least three different second messengers, namely diacylglycerol, calcium and cyclic AMP, are able to activate Rap1 by promoting its release of the guanine nucleotide GDP and its binding to GTP.	Guanosine Diphosphate	168-171	RAP1A, member of RAS oncogene family	Homo sapiens	112-116