PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9751146-0	1998	Delta9-tetrahydrocannabinol increases sequence-specific AP-1 DNA-binding activity and Fos-related antigens in the rat brain.	Dronabinol	0-27	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	86-89	
9751146-3	1998	One hour after the intraperitoneal administration of delta9-THC at a dose of 10 or 15 mg/kg, AP-1 DNA-binding activity in the nucleus accumbens increased by 33 and 49%, respectively, while Western blot showed an increase in both c-Fos, FosB, Fra-1 (Fos-related antigen) and Fra-2.	Dronabinol	53-63	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	229-234	
9751146-6	1998	The effect of delta9-THC on the AP-1 DNA binding and the Fos-related antigens in the nucleus accumbens was blocked by the specific cannabinoid antagonist SR141716 A (3 mg/kg i.p.).	Dronabinol	14-24	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	57-60	
9751146-8	1998	The results indicate that delta9-THC activates gene coding for AP-1 DNA-binding proteins by acting on cannabinoid receptors, and induces a different transcriptional program on the early-immediate gene of the Fos family, in different areas in the rat brain, suggesting that this mechanism might be involved in the central actions of cannabinoids.	Dronabinol	26-36	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	208-211