PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9742217-1 1998 The role of the functional architecture of the human acetylcholinesterase (HuAChE) active centre in accommodating the non-covalent inhibitors tacrine and huperzine A, or the carbamates pyridostigmine and physostigmine, was analysed using 16 mutants of residues lining the active-centre gorge. Physostigmine 204-217 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73