PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9705280-1 1998 The Rho family GTPases, Rac1 and Rac2, regulate a variety of cellular functions including cytoskeletal reorganization, the generation of reactive oxygen species, G1 cell cycle progression and, in concert with Ras, oncogenic transformation. Reactive Oxygen Species 137-160 Rac family small GTPase 1 Homo sapiens 24-28 9705280-1 1998 The Rho family GTPases, Rac1 and Rac2, regulate a variety of cellular functions including cytoskeletal reorganization, the generation of reactive oxygen species, G1 cell cycle progression and, in concert with Ras, oncogenic transformation. Reactive Oxygen Species 137-160 Rac family small GTPase 2 Homo sapiens 33-37 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 Rac family small GTPase 1 Homo sapiens 86-90 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 Rac family small GTPase 2 Homo sapiens 95-99 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 p21 (RAC1) activated kinase 1 Homo sapiens 136-140 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 Rac family small GTPase 1 Homo sapiens 155-159 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 Rac family small GTPase 2 Homo sapiens 161-165 9705280-10 1998 Mutation of these Lys residues to neutral residues decreased PAK binding to activated Rac1 and Rac2 (but not Cdc42) and greatly reduced PAK1 activation by Rac1, Rac2, and Cdc42 proteins in vivo. Lysine 18-21 cell division cycle 42 Homo sapiens 171-176