PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9671519-2	1998	While the palmitoyl protein thioesterase(s) responsible for depalmitoylation of plasma membrane-associated signaling proteins has (have) not been identified, the lysosomal palmitoyl protein thioesterase 1 (PPT1) has proven useful in in vitro studies of membrane localization requirements of GTP-binding proteins.	Guanosine Triphosphate	291-294	palmitoyl-protein thioesterase 1	Homo sapiens	172-204	
9671519-2	1998	While the palmitoyl protein thioesterase(s) responsible for depalmitoylation of plasma membrane-associated signaling proteins has (have) not been identified, the lysosomal palmitoyl protein thioesterase 1 (PPT1) has proven useful in in vitro studies of membrane localization requirements of GTP-binding proteins.	Guanosine Triphosphate	291-294	palmitoyl-protein thioesterase 1	Homo sapiens	206-210	
9671519-5	1998	Didemnin B was shown to inhibit recombinant human PPT1 with a Ki of 92 nM.	didemnins	0-10	palmitoyl-protein thioesterase 1	Homo sapiens	50-54	
9671519-6	1998	Kinetic analysis of this inhibition revealed that didemnin B inhibits PPT1 uncompetitively.	didemnins	50-60	palmitoyl-protein thioesterase 1	Homo sapiens	70-74	
9671519-8	1998	As the first described inhibitor of PPT1, didemnin B may prove to be a useful tool in the investigation of protein palmitoylation regulation.	didemnins	42-52	palmitoyl-protein thioesterase 1	Homo sapiens	36-40