PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9658732-6 1998 STATE OF ART AND PERSPECTIVE: HC is now recognized as the genetic disease characterized by the homozygosity for the Cys-->Tyr substitution at position 282 (C282Y) of the HFE protein. Cysteine 116-119 homeostatic iron regulator Homo sapiens 173-176