PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9628743-2 1998 A specific protein-DNA complex, termed DRP-3, was identified in an electrophoretic mobility shift assay (EMSA) using a cisplatin-damaged DNA probe. Cisplatin 119-128 dihydropyrimidinase like 3 Homo sapiens 39-44 9628743-10 1998 Therefore, we assessed how another cisplatin DNA binding protein, HMG-1, affected the ability of rhRPA to bind damaged DNA. Cisplatin 35-44 high mobility group box 1 pseudogene 5 Homo sapiens 66-71 9628743-12 1998 Simultaneous addition experiments revealed that HMG-1 binding to cisplatin-damaged DNA was minimally affected by rhRPA, while HMG-1 inhibited the damaged-DNA binding activity of rhRPA. Cisplatin 65-74 high mobility group box 1 pseudogene 5 Homo sapiens 48-53 9628743-13 1998 These data are consistent with HMG-1 blocking DNA repair and possibly having the capability to enhance the cytotoxic efficacy of the drug cisplatin. Cisplatin 138-147 high mobility group box 1 pseudogene 5 Homo sapiens 31-36