PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9596684-1	1998	Thymidylate synthase (TS) inhibition causes cell death, and this enzyme is the target for the important chemotherapy regime 5-fluorouracil/leucovorin.	Fluorouracil	124-138	thymidylate synthetase	Homo sapiens	0-20	
9596684-1	1998	Thymidylate synthase (TS) inhibition causes cell death, and this enzyme is the target for the important chemotherapy regime 5-fluorouracil/leucovorin.	Fluorouracil	124-138	thymidylate synthetase	Homo sapiens	22-24	
9596684-1	1998	Thymidylate synthase (TS) inhibition causes cell death, and this enzyme is the target for the important chemotherapy regime 5-fluorouracil/leucovorin.	Leucovorin	139-149	thymidylate synthetase	Homo sapiens	0-20	
9596684-1	1998	Thymidylate synthase (TS) inhibition causes cell death, and this enzyme is the target for the important chemotherapy regime 5-fluorouracil/leucovorin.	Leucovorin	139-149	thymidylate synthetase	Homo sapiens	22-24	
9596684-2	1998	GW1843 (1843U89) is a potent and specific folate analog TS inhibitor in clinical development.	1843U89	0-6	thymidylate synthetase	Homo sapiens	56-58	
9596684-2	1998	GW1843 (1843U89) is a potent and specific folate analog TS inhibitor in clinical development.	1843U89	8-15	thymidylate synthetase	Homo sapiens	56-58	
9596684-3	1998	Because of the importance of TS as a chemotherapy target, we are studying the mechanism of TS inhibition-induced cell death by GW1843.	1843U89	127-133	thymidylate synthetase	Homo sapiens	91-93	
9596684-6	1998	In response to GW1843, Molt-4 cells undergo apoptosis with both acidic pH, Mg2+-independent sphingomyelinase (ASMase) and neutral pH, Mg2+-dependent sphingomyelinase (NSMase) activities elevated as early steps in the initiation of apoptosis before Molt-4 commitment to death.	1843U89	15-21	sphingomyelin phosphodiesterase 1	Homo sapiens	110-116	
9596684-6	1998	In response to GW1843, Molt-4 cells undergo apoptosis with both acidic pH, Mg2+-independent sphingomyelinase (ASMase) and neutral pH, Mg2+-dependent sphingomyelinase (NSMase) activities elevated as early steps in the initiation of apoptosis before Molt-4 commitment to death.	1843U89	15-21	sphingomyelin phosphodiesterase 2	Homo sapiens	167-173