PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9536026-0 1998 Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. Valproic Acid 0-16 myristoylated alanine rich protein kinase C substrate Homo sapiens 36-81 9536026-0 1998 Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. Valproic Acid 0-16 myristoylated alanine rich protein kinase C substrate Homo sapiens 83-89 9536026-5 1998 Our current results demonstrated that valproate induces a concentration- and time-dependent reduction of MARCKS in immortalized hippocampal cells that appears to be independent of both the level of muscarinic receptor-activated PI signaling as well as the concentration of myo-inositol. Valproic Acid 38-47 myristoylated alanine rich protein kinase C substrate Homo sapiens 105-111 9536026-8 1998 Furthermore, the effect on MARCKS protein is additive in the presence of therapeutic concentrations of both lithium and valproate, consistent with clinical observations regarding the enhanced efficacy of the combination treatment. Valproic Acid 120-129 myristoylated alanine rich protein kinase C substrate Homo sapiens 27-33