PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9528967-0	1998	Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Signal transducers and activators of transcription (Stat) proteins are latent cytoplasmic transcription factors that are tyrosine phosphorylated by Janus kinases (Jak) in response to GH and other cytokines.	Tyrosine	315-323	gonadotropin releasing hormone receptor	Rattus norvegicus	23-37	
9528967-0	1998	Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Signal transducers and activators of transcription (Stat) proteins are latent cytoplasmic transcription factors that are tyrosine phosphorylated by Janus kinases (Jak) in response to GH and other cytokines.	Tyrosine	315-323	Janus kinase 2	Rattus norvegicus	46-60	
9528967-0	1998	Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Signal transducers and activators of transcription (Stat) proteins are latent cytoplasmic transcription factors that are tyrosine phosphorylated by Janus kinases (Jak) in response to GH and other cytokines.	Tyrosine	315-323	Janus kinase 2	Rattus norvegicus	62-67	
9528967-0	1998	Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Signal transducers and activators of transcription (Stat) proteins are latent cytoplasmic transcription factors that are tyrosine phosphorylated by Janus kinases (Jak) in response to GH and other cytokines.	Tyrosine	315-323	signal transducer and activator of transcription 5A	Rattus norvegicus	69-119	
9528967-0	1998	Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2)/signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C. Signal transducers and activators of transcription (Stat) proteins are latent cytoplasmic transcription factors that are tyrosine phosphorylated by Janus kinases (Jak) in response to GH and other cytokines.	Tyrosine	315-323	signal transducer and activator of transcription 5A	Rattus norvegicus	121-126	
9528967-1	1998	GH activates Stat5 by a mechanism that involves tyrosine phosphorylation and nuclear translocation.	Tyrosine	48-56	signal transducer and activator of transcription 5A	Rattus norvegicus	13-18	
9528967-10	1998	However, Jak2 tyrosine phosphorylation and Stat5 DNA-binding activity were prolonged for at least 4 h in the presence of cycloheximide, which suggests that the maintenance of desensitization requires ongoing protein synthesis.	Tyrosine	14-22	Janus kinase 2	Rattus norvegicus	9-13	
9528967-10	1998	However, Jak2 tyrosine phosphorylation and Stat5 DNA-binding activity were prolonged for at least 4 h in the presence of cycloheximide, which suggests that the maintenance of desensitization requires ongoing protein synthesis.	Cycloheximide	121-134	Janus kinase 2	Rattus norvegicus	9-13	
9528967-10	1998	However, Jak2 tyrosine phosphorylation and Stat5 DNA-binding activity were prolonged for at least 4 h in the presence of cycloheximide, which suggests that the maintenance of desensitization requires ongoing protein synthesis.	Cycloheximide	121-134	signal transducer and activator of transcription 5A	Rattus norvegicus	43-48	
9528967-12	1998	GH-induced Jak2 and Stat5 activation were not affected by D609 or mepacrine, both inhibitors of phospholipase C. However, in the presence of D609 and mepacrine, GH maintained prolonged Jak2 and Stat5 activation.	tricyclodecane-9-yl-xanthogenate	141-145	Janus kinase 2	Rattus norvegicus	185-189	
9528967-12	1998	GH-induced Jak2 and Stat5 activation were not affected by D609 or mepacrine, both inhibitors of phospholipase C. However, in the presence of D609 and mepacrine, GH maintained prolonged Jak2 and Stat5 activation.	tricyclodecane-9-yl-xanthogenate	141-145	signal transducer and activator of transcription 5A	Rattus norvegicus	194-199	
9528967-12	1998	GH-induced Jak2 and Stat5 activation were not affected by D609 or mepacrine, both inhibitors of phospholipase C. However, in the presence of D609 and mepacrine, GH maintained prolonged Jak2 and Stat5 activation.	Quinacrine	150-159	Janus kinase 2	Rattus norvegicus	185-189	
9528967-12	1998	GH-induced Jak2 and Stat5 activation were not affected by D609 or mepacrine, both inhibitors of phospholipase C. However, in the presence of D609 and mepacrine, GH maintained prolonged Jak2 and Stat5 activation.	Quinacrine	150-159	signal transducer and activator of transcription 5A	Rattus norvegicus	194-199