PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9488041-0	1998	Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells.	ursolic acid	0-12	matrix metallopeptidase 9	Homo sapiens	40-45	
9488041-1	1998	We have previously reported that ursolic acid, a pentacyclic triterpene acid, inhibited the invasion of HT1080 human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9.	ursolic acid	33-45	matrix metallopeptidase 9	Homo sapiens	166-192	
9488041-6	1998	Similarly, ursolic acid down-regulated 2-O-tetradecanoylphorbol-acetate-induction of matrix metalloproteinase-9 gene in the same manner of dexamethasone.	ursolic acid	11-23	matrix metallopeptidase 9	Homo sapiens	85-111	
9488041-7	1998	RU486, a potent glucocorticoid receptor antagonist, was used for identifying that ursolic acid-induced down-regulation of matrix metalloproteinase-9 expression is mediated by its binding to glucocorticoid receptor.	ursolic acid	82-94	matrix metallopeptidase 9	Homo sapiens	122-148	
9488041-8	1998	The effect of ursolic acid on the matrix metalloproteinase-9 expression was blocked by RU486, suggesting that ursolic acid acts via a glucocorticoid receptor in the regulation of matrix metalloproteinase-9.	ursolic acid	14-26	matrix metallopeptidase 9	Homo sapiens	34-60	
9488041-8	1998	The effect of ursolic acid on the matrix metalloproteinase-9 expression was blocked by RU486, suggesting that ursolic acid acts via a glucocorticoid receptor in the regulation of matrix metalloproteinase-9.	ursolic acid	14-26	matrix metallopeptidase 9	Homo sapiens	179-205	
9488041-8	1998	The effect of ursolic acid on the matrix metalloproteinase-9 expression was blocked by RU486, suggesting that ursolic acid acts via a glucocorticoid receptor in the regulation of matrix metalloproteinase-9.	ursolic acid	110-122	matrix metallopeptidase 9	Homo sapiens	34-60	
9488041-8	1998	The effect of ursolic acid on the matrix metalloproteinase-9 expression was blocked by RU486, suggesting that ursolic acid acts via a glucocorticoid receptor in the regulation of matrix metalloproteinase-9.	ursolic acid	110-122	matrix metallopeptidase 9	Homo sapiens	179-205	
9488041-11	1998	Taken together, we suggest that ursolic acid may induce the repression of matrix metalloproteinase-9 by stimulating the nuclear translocation of glucocorticoid receptor, and the translocated glucocorticoid receptor probably down-modulating the trans-activating function of AP-1 to 2-O-tetradecanoylphorbol-acetate responsible element of matrix metalloproteinase-9 promoter region.	ursolic acid	32-44	matrix metallopeptidase 9	Homo sapiens	74-100	
9488041-11	1998	Taken together, we suggest that ursolic acid may induce the repression of matrix metalloproteinase-9 by stimulating the nuclear translocation of glucocorticoid receptor, and the translocated glucocorticoid receptor probably down-modulating the trans-activating function of AP-1 to 2-O-tetradecanoylphorbol-acetate responsible element of matrix metalloproteinase-9 promoter region.	ursolic acid	32-44	matrix metallopeptidase 9	Homo sapiens	337-363