PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9486655-4	1998	However, treatment with RA induces differentiation of leukaemic blast cells and disease remission in PML-RARalpha APLs, whereas PLZF-RARa APLs are resistant to RA.	Tretinoin	24-26	PML nuclear body scaffold	Homo sapiens	101-104	
9486655-4	1998	However, treatment with RA induces differentiation of leukaemic blast cells and disease remission in PML-RARalpha APLs, whereas PLZF-RARa APLs are resistant to RA.	Tretinoin	24-26	retinoic acid receptor alpha	Homo sapiens	105-113	
9486655-4	1998	However, treatment with RA induces differentiation of leukaemic blast cells and disease remission in PML-RARalpha APLs, whereas PLZF-RARa APLs are resistant to RA.	Tretinoin	24-26	retinoic acid receptor alpha	Homo sapiens	105-109	
9486655-4	1998	However, treatment with RA induces differentiation of leukaemic blast cells and disease remission in PML-RARalpha APLs, whereas PLZF-RARa APLs are resistant to RA.	Tretinoin	105-107	PML nuclear body scaffold	Homo sapiens	101-104	
9486655-7	1998	PLZF-RARalpha contains a second, RA-resistant binding site in the PLZF amino-terminal region.	Tretinoin	5-7	zinc finger and BTB domain containing 16	Homo sapiens	0-4	
9486655-7	1998	PLZF-RARalpha contains a second, RA-resistant binding site in the PLZF amino-terminal region.	Tretinoin	5-7	zinc finger and BTB domain containing 16	Homo sapiens	66-70	
9486655-8	1998	High doses of RA release histone deacetylase activity from PML-RARalpha, but not from PLZF-RARalpha.	Tretinoin	14-16	PML nuclear body scaffold	Homo sapiens	59-62	
9486655-8	1998	High doses of RA release histone deacetylase activity from PML-RARalpha, but not from PLZF-RARalpha.	Tretinoin	14-16	retinoic acid receptor alpha	Homo sapiens	63-71	
9486655-10	1998	Therefore, recruitment of histone deacetylase is crucial to the transforming potential of APL fusion proteins, and the different effects of RA on the stability of the PML-RARalpha and PLZF-RARalpha co-repressor complexes determines the differential response of APLs to RA.	Tretinoin	140-142	PML nuclear body scaffold	Homo sapiens	167-170	
9486655-10	1998	Therefore, recruitment of histone deacetylase is crucial to the transforming potential of APL fusion proteins, and the different effects of RA on the stability of the PML-RARalpha and PLZF-RARalpha co-repressor complexes determines the differential response of APLs to RA.	Tretinoin	140-142	retinoic acid receptor alpha	Homo sapiens	171-179	
9486655-10	1998	Therefore, recruitment of histone deacetylase is crucial to the transforming potential of APL fusion proteins, and the different effects of RA on the stability of the PML-RARalpha and PLZF-RARalpha co-repressor complexes determines the differential response of APLs to RA.	Tretinoin	140-142	zinc finger and BTB domain containing 16	Homo sapiens	184-188	
9486655-10	1998	Therefore, recruitment of histone deacetylase is crucial to the transforming potential of APL fusion proteins, and the different effects of RA on the stability of the PML-RARalpha and PLZF-RARalpha co-repressor complexes determines the differential response of APLs to RA.	Tretinoin	140-142	retinoic acid receptor alpha	Homo sapiens	189-197	
9486655-10	1998	Therefore, recruitment of histone deacetylase is crucial to the transforming potential of APL fusion proteins, and the different effects of RA on the stability of the PML-RARalpha and PLZF-RARalpha co-repressor complexes determines the differential response of APLs to RA.	Tretinoin	171-173	PML nuclear body scaffold	Homo sapiens	167-170