PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Nitric Oxide	27-39	Janus kinase 2	Rattus norvegicus	108-112	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Nitric Oxide	27-39	Janus kinase 2	Rattus norvegicus	193-197	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Sulfhydryl Compounds	50-55	Janus kinase 2	Rattus norvegicus	108-112	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Sulfhydryl Compounds	50-55	Janus kinase 2	Rattus norvegicus	193-197	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	dithiol	163-171	Janus kinase 2	Rattus norvegicus	108-112	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	dithiol	163-171	Janus kinase 2	Rattus norvegicus	193-197	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Disulfides	175-185	Janus kinase 2	Rattus norvegicus	108-112	
9419340-3	1998	Herein we demonstrate that nitric oxide and other thiol oxidants can inhibit the autokinase activity of rat JAK2 in vitro, presumably through oxidation of crucial dithiols to disulfides within JAK2.	Disulfides	175-185	Janus kinase 2	Rattus norvegicus	193-197	
9419340-5	1998	Nitric oxide pretreatment of quiescent Ba/F3 cells also inhibits the interleukin 3-triggered in vivo activation of JAK2, a phenomenon that correlates with inhibited proliferation.	Nitric Oxide	0-12	interleukin 3	Mus musculus	69-82	
9419340-5	1998	Nitric oxide pretreatment of quiescent Ba/F3 cells also inhibits the interleukin 3-triggered in vivo activation of JAK2, a phenomenon that correlates with inhibited proliferation.	Nitric Oxide	0-12	Janus kinase 2	Mus musculus	115-119	
9419340-6	1998	Furthermore, we observed that the autokinase activity of JAK3 responds in a similar fashion to thiol redox reagents in vitro and to nitric oxide donors in vivo.	Sulfhydryl Compounds	95-100	Janus kinase 3	Rattus norvegicus	57-61	
9419340-6	1998	Furthermore, we observed that the autokinase activity of JAK3 responds in a similar fashion to thiol redox reagents in vitro and to nitric oxide donors in vivo.	Nitric Oxide	132-144	Janus kinase 3	Rattus norvegicus	57-61	
9419340-7	1998	We suggest that the thiol redox regulation of JAKs may partially explain the generally immunosuppressive effects of nitric oxide and of other thiol oxidants.	Sulfhydryl Compounds	20-25	Janus kinase 2	Mus musculus	46-50	
9419340-7	1998	We suggest that the thiol redox regulation of JAKs may partially explain the generally immunosuppressive effects of nitric oxide and of other thiol oxidants.	Nitric Oxide	116-128	Janus kinase 2	Mus musculus	46-50	
9419340-7	1998	We suggest that the thiol redox regulation of JAKs may partially explain the generally immunosuppressive effects of nitric oxide and of other thiol oxidants.	Sulfhydryl Compounds	142-147	Janus kinase 2	Mus musculus	46-50