PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9367827-1	1997	The human monocytic leukemic cell line, THP-1, which differentiates toward macrophages in response to phorbol 12-myristate 13-acetate (PMA) was investigated for its ability to produce granulocyte colony-stimulating factor (G-CSF).	Tetradecanoylphorbol Acetate	135-138	colony stimulating factor 3	Homo sapiens	184-221	
9367827-2	1997	G-CSF protein was neither produced during PMA-induced differentiation nor in response to dexamethasone (Dex) alone.	Tetradecanoylphorbol Acetate	42-45	colony stimulating factor 3	Homo sapiens	0-5	
9367827-3	1997	However, when combined, PMA and Dex synergistically stimulated THP-1 cells to produce G-CSF.	Tetradecanoylphorbol Acetate	24-27	colony stimulating factor 3	Homo sapiens	86-91	
9367827-4	1997	The synergistic interaction between PMA and Dex on G-CSF production appeared to be mediated through the production of interleukin-1 (IL-1) since neutralization of IL-1 activity completely inhibited G-CSF production.	Tetradecanoylphorbol Acetate	36-39	colony stimulating factor 3	Homo sapiens	51-56	
9367827-4	1997	The synergistic interaction between PMA and Dex on G-CSF production appeared to be mediated through the production of interleukin-1 (IL-1) since neutralization of IL-1 activity completely inhibited G-CSF production.	Tetradecanoylphorbol Acetate	36-39	colony stimulating factor 3	Homo sapiens	198-203	
9367827-5	1997	Further experiments demonstrated that in THP-1 cells pretreated with PMA, Dex potently synergized with IL-1 to stimulate G-CSF production.	Tetradecanoylphorbol Acetate	69-72	colony stimulating factor 3	Homo sapiens	121-126