PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9365020-0 1997 Prostaglandin E2 may induce hyperthermia through EP1 receptor in the anterior wall of the third ventricle and neighboring preoptic regions. Dinoprostone 0-16 prostaglandin E receptor 1 Rattus norvegicus 49-52 9365020-1 1997 We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. Dinoprostone 70-86 prostaglandin E receptor 1 Rattus norvegicus 132-135 9365020-1 1997 We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. Dinoprostone 88-92 prostaglandin E receptor 1 Rattus norvegicus 132-135 9365020-2 1997 In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phenyl-omega-trinor PGE2 (17-Ph-PGE2, 100 ng) into different sites in the rat brain and observed the colonic temperature (Tco) for 2 h in a 23 +/- 1 degrees C environment. Dinoprostone 64-68 prostaglandin E receptor 1 Rattus norvegicus 98-101 9365020-2 1997 In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phenyl-omega-trinor PGE2 (17-Ph-PGE2, 100 ng) into different sites in the rat brain and observed the colonic temperature (Tco) for 2 h in a 23 +/- 1 degrees C environment. Dinoprostone 64-68 prostaglandin E receptor 1 Rattus norvegicus 133-136 9365020-6 1997 Intracerebroventricular pretreatment with SC-19220 (an EP1 antagonist, 100 microg) inhibited the rise in the Tco which was induced by microinjection of PGE2 (50 ng) into the A3V. Dinoprostone 152-156 prostaglandin E receptor 1 Rattus norvegicus 55-58 9365020-7 1997 These results thus suggest that PGE2 induces hyperthermia by stimulating EP1 receptors in the A3V and the neighboring preoptic region. Dinoprostone 32-36 prostaglandin E receptor 1 Rattus norvegicus 73-76