PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9361344-4 1997 Similar results were achieved by systemic administration of CNI-1493, a recently described tetravalent guanylhydrazone compound, which effectively inhibited endogenous brain TNF synthesis and conferred significant protection against the development of cerebral infarction (80% reduced infarct volume as compared with vehicle controls treated 1 h postischemia with 10 mg/kg). Mitoguazone 103-118 tumor necrosis factor-like Rattus norvegicus 174-177