PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9357850-0	1997	Involvement of the ICE family of proteases in silica-induced apoptosis in human alveolar macrophages.	Silicon Dioxide	46-52	caspase 1	Homo sapiens	19-22	
9357850-8	1997	Additionally, an increased formation of the active p20 fragments of ICE and Ich-1L as well as degradation of the inactive zymogen form of cpp32beta protein were observed in silica-treated human alveolar macrophages, indicating activation of these proteases.	Silicon Dioxide	173-179	caspase 1	Homo sapiens	68-71	
9357850-10	1997	These results suggest that silica-induced apoptosis involves activation of the ICE family of proteases and is the first step in elucidating the intracellular mechanism of particulate-induced apoptosis in human alveolar macrophages.	Silicon Dioxide	27-33	caspase 1	Homo sapiens	79-82