PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9354392-0 1997 Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors. Nitric Oxide 68-80 heme oxygenase 1 Homo sapiens 48-64 9354392-1 1997 To explore the involvement of nitric oxide (NO) in the induction of heme oxygenase-1, an essential enzyme in heme catabolism, we studied the effects of NO donors on the expression of heme oxygenase-1 mRNA in HeLa human cervical cancer cells. Nitric Oxide 30-42 heme oxygenase 1 Homo sapiens 68-84 9354392-2 1997 Treatment with each of three NO donors, sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-L-glutathione, caused noticeable increases in the expression levels of heme oxygenase- mRNA, but not heme oxygenase-2 mRNA. Nitroprusside 40-60 heme oxygenase 2 Homo sapiens 202-218 9354392-2 1997 Treatment with each of three NO donors, sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-L-glutathione, caused noticeable increases in the expression levels of heme oxygenase- mRNA, but not heme oxygenase-2 mRNA. linsidomine 62-85 heme oxygenase 2 Homo sapiens 202-218 9354392-2 1997 Treatment with each of three NO donors, sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-L-glutathione, caused noticeable increases in the expression levels of heme oxygenase- mRNA, but not heme oxygenase-2 mRNA. S-Nitrosoglutathione 91-114 heme oxygenase 2 Homo sapiens 202-218 9354392-4 1997 We showed that sodium nitroprusside also increased the levels of heme oxygenase-1 protein. Nitroprusside 15-35 heme oxygenase 1 Homo sapiens 65-81 9354392-5 1997 The sodium nitroprusside-mediated increase in heme oxygenase-1 mRNA levels was abolished by treatment with actinomycin D. Nitroprusside 4-24 heme oxygenase 1 Homo sapiens 46-62 9354392-5 1997 The sodium nitroprusside-mediated increase in heme oxygenase-1 mRNA levels was abolished by treatment with actinomycin D. Dactinomycin 107-120 heme oxygenase 1 Homo sapiens 46-62