PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9325011-4 1997 The dependence on Ca2+ in the induction of GM-CSF, but not of apoptosis, was further confirmed by the inhibition of TNF- or IL-1-induced cytokine production by cyclosporin A or FK506, drugs that block the Ca2+/calmodulin-dependent protein Ser/Thr phosphatase calcineurin. Tacrolimus 177-182 tumor necrosis factor Rattus norvegicus 116-119