PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9269990-0 1997 The DNA repair protein O6-methylguanine-DNA methyltransferase protects against skin tumor formation induced by antineoplastic chloroethylnitrosourea. 1-(2-chloroethyl)-1-nitrosourea 126-148 O-6-methylguanine-DNA methyltransferase Mus musculus 23-61 9269990-2 1997 Because secondary tumor formation is a serious threat in chemotherapy with these drugs, we explored whether and to what extent the DNA repair protein DNA-O6-methylguanine:protein-L-cysteine S-methyltransferase (MGMT) protects against CNU-induced tumors. 1-(2-chloroethyl)-1-nitrosourea 234-237 O-6-methylguanine-DNA methyltransferase Mus musculus 150-209 9269990-2 1997 Because secondary tumor formation is a serious threat in chemotherapy with these drugs, we explored whether and to what extent the DNA repair protein DNA-O6-methylguanine:protein-L-cysteine S-methyltransferase (MGMT) protects against CNU-induced tumors. 1-(2-chloroethyl)-1-nitrosourea 234-237 O-6-methylguanine-DNA methyltransferase Mus musculus 211-215 9269990-6 1997 The results provide clear evidence that MGMT exerts protection against CNU-induced cancer. 1-(2-chloroethyl)-1-nitrosourea 71-74 O-6-methylguanine-DNA methyltransferase Mus musculus 40-44 9269990-7 1997 Our data also indicate that O6-chloroethylguanine, which is repaired by MGMT, is a main precarcinogenic CNU-induced DNA lesion. 1-(2-chloroethyl)-1-nitrosourea 104-107 O-6-methylguanine-DNA methyltransferase Mus musculus 72-76