PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9241755-2 1997 In vivo, epinephrine and the vasopressin analog DDAVP increase vWf plasma levels, although they are thought not to induce vWf release from endothelial cells in vitro. Epinephrine 9-20 von Willebrand factor Homo sapiens 63-66 9241755-7 1997 Epinephrine (together with IBMX) caused a small, dose-dependent increase in vWf release, maximal at 10(-6) M (+50%), and also potentiated the response to thrombin. Epinephrine 0-11 von Willebrand factor Homo sapiens 76-79 9241755-11 1997 We found a close correlation between cellular cAMP content and vWf release after stimulation with epinephrine and forskolin. Epinephrine 98-109 von Willebrand factor Homo sapiens 63-66 9241755-12 1997 These results demonstrate that cAMP-dependent signaling events are involved in the control of exocytosis from endothelial cells (an effect not mediated by an increase in [Ca2+]i) and provide an explanation for epinephrine-induced vWf release. Epinephrine 210-221 von Willebrand factor Homo sapiens 230-233