PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9235956-3 1997 When quiescent cultures of bovine fibroblasts were stimulated with 10 nM IGF-I and total cell lysates immunoblotted with anti-phosphotyrosine antibody, we observed a band at approximately 97 kDa, representing the beta-subunit of the IGF-I receptor, and a predominant tyrosyl-phosphorylated species migrating as a broad band between 170 and 190 kDa. Phosphotyrosine 126-141 insulin like growth factor 1 Bos taurus 73-78 9235956-3 1997 When quiescent cultures of bovine fibroblasts were stimulated with 10 nM IGF-I and total cell lysates immunoblotted with anti-phosphotyrosine antibody, we observed a band at approximately 97 kDa, representing the beta-subunit of the IGF-I receptor, and a predominant tyrosyl-phosphorylated species migrating as a broad band between 170 and 190 kDa. Phosphotyrosine 126-141 insulin like growth factor 1 Bos taurus 233-238 9235956-3 1997 When quiescent cultures of bovine fibroblasts were stimulated with 10 nM IGF-I and total cell lysates immunoblotted with anti-phosphotyrosine antibody, we observed a band at approximately 97 kDa, representing the beta-subunit of the IGF-I receptor, and a predominant tyrosyl-phosphorylated species migrating as a broad band between 170 and 190 kDa. cyclo(tyrosyl-tyrosyl) 267-274 insulin like growth factor 1 Bos taurus 73-78 9235956-5 1997 Pretreatment of bovine fibroblasts with 10 nM insulin for 48 h blocked subsequent IGF-I-stimulated DNA synthesis and the IGF-I-induced increase in tyrosyl-phosphorylated IRS-2. cyclo(tyrosyl-tyrosyl) 147-154 insulin Bos taurus 46-53 9235956-5 1997 Pretreatment of bovine fibroblasts with 10 nM insulin for 48 h blocked subsequent IGF-I-stimulated DNA synthesis and the IGF-I-induced increase in tyrosyl-phosphorylated IRS-2. cyclo(tyrosyl-tyrosyl) 147-154 insulin like growth factor 1 Bos taurus 121-126 9235956-5 1997 Pretreatment of bovine fibroblasts with 10 nM insulin for 48 h blocked subsequent IGF-I-stimulated DNA synthesis and the IGF-I-induced increase in tyrosyl-phosphorylated IRS-2. cyclo(tyrosyl-tyrosyl) 147-154 insulin receptor substrate 2 Bos taurus 170-175 9235956-7 1997 The interleukin-4 (IL-4) cytokine receptor also has IRS-2 as its major substrate for tyrosine phosphorylation. Tyrosine 85-93 interleukin 4 Bos taurus 4-17 9235956-7 1997 The interleukin-4 (IL-4) cytokine receptor also has IRS-2 as its major substrate for tyrosine phosphorylation. Tyrosine 85-93 interleukin 4 Bos taurus 19-23 9235956-7 1997 The interleukin-4 (IL-4) cytokine receptor also has IRS-2 as its major substrate for tyrosine phosphorylation. Tyrosine 85-93 insulin receptor substrate 2 Bos taurus 52-57 9235956-10 1997 Insulin-induced desensitization could be prevented if a specific inhibitor of phosphatidylinositol 3-kinase (LY294002), but not an inhibitor of mitogen-activated protein kinase (PD98059), was present during the preincubation period. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 109-117 insulin Bos taurus 0-7 9235956-11 1997 LY294002 also prevented the shift in IRS-2 molecular mass in response to prolonged incubation of cells with insulin. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 0-8 insulin receptor substrate 2 Bos taurus 37-42 9235956-11 1997 LY294002 also prevented the shift in IRS-2 molecular mass in response to prolonged incubation of cells with insulin. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 0-8 insulin Bos taurus 108-115