PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9177409-4 1997 This exon skipping alters the translational reading frame of exon 8 and introduces a premature stop codon (TAA) at amino acid position 410 proximal to the heme iron-binding site essential for the enzymatic activity of CYP17. Iron 160-164 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 218-223