PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9170147-0 1997 Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4"-hydroxylation activities in livers of Japanese and Caucasian populations. Tolbutamide 51-62 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 21-27 9170147-10 1997 Good correlations were found between levels of CYP2C9 and activities of tolbutamide methyl hydroxylation (r = 0.77) and between levels of CYP2C19 and activities of S-mephenytoin 4"-hydroxylation (r = 0.86) in liver microsomes of the human samples examined. Tolbutamide 72-83 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 47-53 9170147-11 1997 Tolbutamide methyl hydroxylation activities were lower in human samples with the Leu359 allele of CYP2C9 than those with the Cys144 allele and wild-type (Arg144-Ile359); the former type showed slightly higher K(m) values. Tolbutamide 0-11 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 98-104