PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9148901-0	1997	Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells.	Daunorubicin	0-12	nuclear factor kappa B subunit 1	Homo sapiens	23-31	
9148901-3	1997	Since the generation of ceramide has been directly linked with the activation of the transcription factor, NFkappaB, this was investigated as a novel target for the action of daunorubicin.	Daunorubicin	175-187	nuclear factor kappa B subunit 1	Homo sapiens	107-115	
9148901-4	1997	Here we describe how treatment of HL-60 promyelocytes and Jurkat T lymphoma cells with daunorubicin results in the activation of the transcription factor NFkappaB.	Daunorubicin	87-99	nuclear factor kappa B subunit 1	Homo sapiens	154-162	
9148901-7	1997	Daunorubicin also induced IkappaB degradation and increased the expression of an NFkappaB-linked reporter gene.	Daunorubicin	0-12	nuclear factor kappa B subunit 1	Homo sapiens	81-89	
9148901-13	1997	These data therefore suggest that the effect of daunorubicin on NFkappaB is unlikely to involve ceramide, but may involve reactive oxygen species generated as a result of endogenous cellular processes rather than reductive metabolism of the drug.	Daunorubicin	48-60	nuclear factor kappa B subunit 1	Homo sapiens	64-72