PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9139732-4 1997 Notably, two neighboring pRB phosphate acceptors, threonine 821 and threonine 826, which have previously been implicated in the regulation of LXCXE protein binding, are phosphorylated by different CDKs. Threonine 50-59 cyclin dependent kinase 2 Homo sapiens 197-201 9139732-4 1997 Notably, two neighboring pRB phosphate acceptors, threonine 821 and threonine 826, which have previously been implicated in the regulation of LXCXE protein binding, are phosphorylated by different CDKs. Threonine 68-77 cyclin dependent kinase 2 Homo sapiens 197-201 9139732-5 1997 We demonstrate that phosphorylation by either CDK2-cyclin A, which phosphorylates T821, or CDK4-cyclin D1, which phosphorylates threonine 826, can disable pRB for subsequent binding of an LXCXE protein. Threonine 128-137 cyclin dependent kinase 2 Homo sapiens 46-50