PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9027729-2	1997	Recently, ROS have been shown to suppress the in vitro synthesis of erythropoietin (Epo).	ros	10-13	erythropoietin	Rattus norvegicus	68-82	
9027729-2	1997	Recently, ROS have been shown to suppress the in vitro synthesis of erythropoietin (Epo).	ros	10-13	erythropoietin	Rattus norvegicus	84-87	
9027729-6	1997	Epo secretion significantly increased to 674 +/- 92 mU/g kidney (N = 7) when vitamins A (0.5 microgram/ml), E (0.5 microgram/ml) and C (10 micrograms/ml) in combination were added to the perfusion medium.	Vitamin A	77-87	erythropoietin	Rattus norvegicus	0-3	
9027729-8	1997	Vitamin A induced a dose-dependent increase (half-maximal stimulation at 0.2 microgram/ml) in the production of immunoreactive Epo during 24 hours of incubation (such as 680 +/- 51 U Epo/g cell protein in HepG2 cultures with 3 micrograms/ml retinol acetate compared to 261 +/- 15 U/g in untreated controls; N = 4).	Vitamin A	0-9	erythropoietin	Rattus norvegicus	127-130	
9027729-8	1997	Vitamin A induced a dose-dependent increase (half-maximal stimulation at 0.2 microgram/ml) in the production of immunoreactive Epo during 24 hours of incubation (such as 680 +/- 51 U Epo/g cell protein in HepG2 cultures with 3 micrograms/ml retinol acetate compared to 261 +/- 15 U/g in untreated controls; N = 4).	Vitamin A	0-9	erythropoietin	Rattus norvegicus	183-186	
9027729-8	1997	Vitamin A induced a dose-dependent increase (half-maximal stimulation at 0.2 microgram/ml) in the production of immunoreactive Epo during 24 hours of incubation (such as 680 +/- 51 U Epo/g cell protein in HepG2 cultures with 3 micrograms/ml retinol acetate compared to 261 +/- 15 U/g in untreated controls; N = 4).	retinol acetate	241-256	erythropoietin	Rattus norvegicus	127-130	
9027729-10	1997	Thus, while vitamins E and C may have the potential to protect cells from oxidative damage, vitamin A exerts a specific stimulation of Epo production.	Vitamin A	92-101	erythropoietin	Rattus norvegicus	135-138	
9027729-11	1997	Preliminary evidence suggests that this effect of vitamin A involves increased mRNA levels of hypoxia-inducible factor 1 alpha (HIF-1 alpha).	Vitamin A	50-59	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	94-126	
9027729-11	1997	Preliminary evidence suggests that this effect of vitamin A involves increased mRNA levels of hypoxia-inducible factor 1 alpha (HIF-1 alpha).	Vitamin A	50-59	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	128-139