PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9020878-0 1997 Neuropeptide Y modulates ATP-induced increases in internal calcium via the adenylate cyclase/protein kinase A system in a human neuroblastoma cell line. Adenosine Triphosphate 25-28 neuropeptide Y Homo sapiens 0-14 9020878-0 1997 Neuropeptide Y modulates ATP-induced increases in internal calcium via the adenylate cyclase/protein kinase A system in a human neuroblastoma cell line. Calcium 59-66 neuropeptide Y Homo sapiens 0-14 9020878-1 1997 The modulatory effects of neuropeptide Y (NPY) on ATP-induced increases in cytosolic free-calcium concentration ([Ca2+]i) were investigated in the CHP-234 human neuroblastoma cell line. Adenosine Triphosphate 50-53 neuropeptide Y Homo sapiens 42-45 9020878-1 1997 The modulatory effects of neuropeptide Y (NPY) on ATP-induced increases in cytosolic free-calcium concentration ([Ca2+]i) were investigated in the CHP-234 human neuroblastoma cell line. Calcium 90-97 neuropeptide Y Homo sapiens 42-45 9020878-2 1997 Pretreatment of cells with 100 nM NPY potentiated the increase in [Ca2+]i evoked subsequently by 20 microM ATP, compared with initial application of ATP in a control experiment, whereas a similar pretreatment with 1 microM NPY attenuated the subsequent response to ATP. Adenosine Triphosphate 107-110 neuropeptide Y Homo sapiens 34-37 9020878-2 1997 Pretreatment of cells with 100 nM NPY potentiated the increase in [Ca2+]i evoked subsequently by 20 microM ATP, compared with initial application of ATP in a control experiment, whereas a similar pretreatment with 1 microM NPY attenuated the subsequent response to ATP. Adenosine Triphosphate 149-152 neuropeptide Y Homo sapiens 34-37 9020878-2 1997 Pretreatment of cells with 100 nM NPY potentiated the increase in [Ca2+]i evoked subsequently by 20 microM ATP, compared with initial application of ATP in a control experiment, whereas a similar pretreatment with 1 microM NPY attenuated the subsequent response to ATP. Adenosine Triphosphate 149-152 neuropeptide Y Homo sapiens 34-37 9020878-3 1997 Both actions of NPY were completely blocked by H-89 [N-[2-((3-(4-bromo-phenyl)-2-propenyl)-amino)-ethyl]-5 isoquinoline sulphonamide dihydrochloride], a selective antagonist of protein kinase A. n-[2-((3-(4-bromo-phenyl)-2-propenyl 53-89 neuropeptide Y Homo sapiens 16-19 9020878-3 1997 Both actions of NPY were completely blocked by H-89 [N-[2-((3-(4-bromo-phenyl)-2-propenyl)-amino)-ethyl]-5 isoquinoline sulphonamide dihydrochloride], a selective antagonist of protein kinase A. -amino)-ethyl]-5 isoquinoline sulphonamide dihydrochloride 90-148 neuropeptide Y Homo sapiens 16-19 9020878-4 1997 The effects of 100 nM NPY were mimicked by H-89, while forskolin and 8-Br-cAMP mimicked the effects of 1 microM NPY. Colforsin 55-64 neuropeptide Y Homo sapiens 112-115 9020878-4 1997 The effects of 100 nM NPY were mimicked by H-89, while forskolin and 8-Br-cAMP mimicked the effects of 1 microM NPY. 8-Bromo Cyclic Adenosine Monophosphate 69-78 neuropeptide Y Homo sapiens 112-115 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Colforsin 15-24 neuropeptide Y Homo sapiens 73-76 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Colforsin 15-24 neuropeptide Y Homo sapiens 91-94 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Colforsin 15-24 neuropeptide Y receptor Y2 Homo sapiens 130-145 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Cyclic AMP 36-40 neuropeptide Y Homo sapiens 73-76 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Cyclic AMP 36-40 neuropeptide Y Homo sapiens 91-94 9020878-5 1997 Both basal and forskolin-stimulated cAMP levels were inhibited by 100 nM NPY and by 100 nM NPY(13-36), a selective agonist of the NPY Y2-receptor subtype. Cyclic AMP 36-40 neuropeptide Y receptor Y2 Homo sapiens 130-145 9020878-7 1997 It is concluded that NPY has a biphasic modulatory effect on increases in [Ca2+]i produced by ATP, which probably involves the cAMP/protein kinase A cascade. Adenosine Triphosphate 94-97 neuropeptide Y Homo sapiens 21-24