PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8999842-0 1997 Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1. Fatty Acids 0-11 carnitine palmitoyltransferase 1B Rattus norvegicus 31-63 8999842-3 1997 We have therefore studied the regulation of carnitine palmitoyltransferase I (CPT I) gene expression by fatty acids in the pancreatic beta-cell line INS-1 since this enzyme catalyzes the limiting step of fatty acid oxidation in various tissues. Fatty Acids 104-115 carnitine palmitoyltransferase 1B Rattus norvegicus 44-76 8999842-3 1997 We have therefore studied the regulation of carnitine palmitoyltransferase I (CPT I) gene expression by fatty acids in the pancreatic beta-cell line INS-1 since this enzyme catalyzes the limiting step of fatty acid oxidation in various tissues. Fatty Acids 104-115 carnitine palmitoyltransferase 1B Rattus norvegicus 78-83 8999842-3 1997 We have therefore studied the regulation of carnitine palmitoyltransferase I (CPT I) gene expression by fatty acids in the pancreatic beta-cell line INS-1 since this enzyme catalyzes the limiting step of fatty acid oxidation in various tissues. Fatty Acids 104-114 carnitine palmitoyltransferase 1B Rattus norvegicus 44-76 8999842-3 1997 We have therefore studied the regulation of carnitine palmitoyltransferase I (CPT I) gene expression by fatty acids in the pancreatic beta-cell line INS-1 since this enzyme catalyzes the limiting step of fatty acid oxidation in various tissues. Fatty Acids 104-114 carnitine palmitoyltransferase 1B Rattus norvegicus 78-83 8999842-6 1997 It was detectable after 1 h and reached a maximum after 3 h. The induction of CPT I mRNA by fatty acids did not require their oxidation, and 2-bromopalmitate, a nonoxidizable fatty acid, increased CPT I mRNA to the same extent as palmitate. Fatty Acids 92-103 carnitine palmitoyltransferase 1B Rattus norvegicus 78-83 8999842-6 1997 It was detectable after 1 h and reached a maximum after 3 h. The induction of CPT I mRNA by fatty acids did not require their oxidation, and 2-bromopalmitate, a nonoxidizable fatty acid, increased CPT I mRNA to the same extent as palmitate. Fatty Acids 92-102 carnitine palmitoyltransferase 1B Rattus norvegicus 78-83 8999842-9 1997 The half-life of the CPT I transcript was unchanged by fatty acids, and nuclear run-on analysis showed a rapid (less than 45 min) and pronounced transcriptional activation of the CPT I gene by fatty acids. Fatty Acids 193-204 carnitine palmitoyltransferase 1B Rattus norvegicus 179-184 8999842-14 1997 The results indicate that the CPT I gene is an early response gene induced by fatty acids at the transcriptional level in beta- (INS-1) cells. Fatty Acids 78-89 carnitine palmitoyltransferase 1B Rattus norvegicus 30-35