PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8883288-2 1996 The present report shows that prostacyclin and nitroprusside, vasodilator-compounds that enhance the cAMP and cGMP concentration respectively, cause a drastic inhibition of the type IIB vWF-induced platelet responses including increase of cytosolic Ca2+ concentration, phosphorylation of pleckstrin (47 kDa) and myosin light chain (20 kDa), secretion of ATP and serotonin, and aggregation parallel to a decrease of arachidonic acid release. Cyclic AMP 101-105 von Willebrand factor Homo sapiens 186-189