PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8632167-2 1996 We have isolated and purified a brain-derived activity that cleaves the synthetic peptide substrate SEVKMDAEF between methionine and aspartate residues, as required to generate the amino-terminus of beta-amyloid peptide. Aspartic Acid 133-142 amyloid beta precursor protein Homo sapiens 199-219