PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8557169-3 1995 The proprotein convertases are all dependent on calcium for activity and all possess highly conserved subtilisin-like domains with the characteristic catalytic triad of this serine protease (ordered Asp, His, and Ser along the polypeptide chain). Histidine 204-207 coagulation factor II, thrombin Homo sapiens 174-189