PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8523447-0	1995	Cardiac troponin C as a target protein for a novel calcium sensitizing drug, levosimendan.	Simendan	77-89	troponin C1, slow skeletal and cardiac type	Homo sapiens	0-18	
8523447-1	1995	The role of cardiac troponin C (cTnC) as a target protein for the calcium sensitization by levosimendan, pimobendan, MCI-154 and EMD 53998 was evaluated using purified recombinant human cTnC.	Simendan	91-103	troponin C1, slow skeletal and cardiac type	Homo sapiens	12-30	
8523447-1	1995	The role of cardiac troponin C (cTnC) as a target protein for the calcium sensitization by levosimendan, pimobendan, MCI-154 and EMD 53998 was evaluated using purified recombinant human cTnC.	Simendan	91-103	troponin C1, slow skeletal and cardiac type	Homo sapiens	32-36	
8523447-4	1995	Only levosimendan showed calcium-dependent and to a lesser extent magnesium-dependent retention in the cTnC column.	Simendan	5-17	troponin C1, slow skeletal and cardiac type	Homo sapiens	103-107	
8523447-5	1995	The findings indicate that levosimendan binds both to the N-terminal and C-terminal domains of cTnC.	Simendan	27-39	troponin C1, slow skeletal and cardiac type	Homo sapiens	95-99	
8523447-6	1995	In agreement with this, only levosimendan shifted the calcium-induced fluorescence curve of dansylated cTnC to the left.	Simendan	29-41	troponin C1, slow skeletal and cardiac type	Homo sapiens	103-107	
8523447-9	1995	In conclusion, it is suggested that the mechanism of calcium sensitizing effect of levosimendan, unlike that of the other calcium sensitizers, is based on calcium-dependent binding to the N-terminal domain of cTnC.	Simendan	83-95	troponin C1, slow skeletal and cardiac type	Homo sapiens	209-213