PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8387542-6	1993	The effect of metformin, a dimethyl-substituted biguanide, known to lower plasma insulin and PAI-1 levels in vivo was concomitantly evaluated.	Metformin	14-23	serpin family E member 1	Homo sapiens	93-98	
8387542-11	1993	The results indicate that PAI-1 synthesis in presence of insulin is markedly increased in down-regulated cells, and that metformin inhibits this effect by acting at the cellular level.	Metformin	121-130	serpin family E member 1	Homo sapiens	26-31