PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8385106-4	1993	Over a physiologically relevant range of concentrations, GH was found to promote, in 3T3-F442A fibroblasts, rapid changes in the level of tyrosyl phosphorylation of more than 13 proteins.	cyclo(tyrosyl-tyrosyl)	138-145	growth hormone 1	Homo sapiens	57-59	
8385106-5	1993	At the highest GH concentration employed (500 ng/ml), increased tyrosyl phosphorylation of two proteins, pp121 and pp97, was clearly visible at 1 min, the earliest time tested.	cyclo(tyrosyl-tyrosyl)	64-71	growth hormone 1	Homo sapiens	15-17	
8385106-6	1993	Increased tyrosyl phosphorylation of a number of other proteins (pp250, pps160-180, pps140-160, pp130, pp90, pp75, pp45, pp42, pp39, and pp36) and decreased tyrosyl phosphorylation of a 140-kDa protein were apparent after 5-10 min of incubation with GH.	cyclo(tyrosyl-tyrosyl)	10-17	growth hormone 1	Homo sapiens	250-252	
8385106-8	1993	When added to anti-GH antibody immunoprecipitates from GH-treated cells, they inhibited incorporation of 32P from [gamma-32P]ATP into tyrosyl residues in GH receptor complexes.	cyclo(tyrosyl-tyrosyl)	134-141	growth hormone 1	Homo sapiens	19-21	
8385106-8	1993	When added to anti-GH antibody immunoprecipitates from GH-treated cells, they inhibited incorporation of 32P from [gamma-32P]ATP into tyrosyl residues in GH receptor complexes.	cyclo(tyrosyl-tyrosyl)	134-141	growth hormone 1	Homo sapiens	55-57	
8385106-9	1993	When added to cells, all three inhibitors blocked all GH-dependent increases in tyrosyl phosphorylation of cellular proteins.	cyclo(tyrosyl-tyrosyl)	80-87	growth hormone 1	Homo sapiens	54-56	
8385106-12	1993	In contrast, genistein and hydroxy-(2-naphthyl)-methylphosphonic acid, tyrosine kinase inhibitors lacking specificity for the GH receptor-associated kinase, decreased GH-dependent tyrosyl phosphorylation of only a subset of GH-responsive bands and partially blocked GH-dependent activation of MAP kinase.	cyclo(tyrosyl-tyrosyl)	180-187	growth hormone 1	Homo sapiens	126-128	
8385106-12	1993	In contrast, genistein and hydroxy-(2-naphthyl)-methylphosphonic acid, tyrosine kinase inhibitors lacking specificity for the GH receptor-associated kinase, decreased GH-dependent tyrosyl phosphorylation of only a subset of GH-responsive bands and partially blocked GH-dependent activation of MAP kinase.	cyclo(tyrosyl-tyrosyl)	180-187	growth hormone 1	Homo sapiens	167-169	
8385106-12	1993	In contrast, genistein and hydroxy-(2-naphthyl)-methylphosphonic acid, tyrosine kinase inhibitors lacking specificity for the GH receptor-associated kinase, decreased GH-dependent tyrosyl phosphorylation of only a subset of GH-responsive bands and partially blocked GH-dependent activation of MAP kinase.	cyclo(tyrosyl-tyrosyl)	180-187	growth hormone 1	Homo sapiens	167-169	
8385106-13	1993	These data show that increased tyrosyl phosphorylation of specific cellular proteins is a very rapid response to the binding of GH by the cell and most likely involves multiple tyrosine kinases.	cyclo(tyrosyl-tyrosyl)	31-38	growth hormone 1	Homo sapiens	128-130	
8385106-14	1993	Furthermore, inhibition of the GH receptor-associated tyrosine kinase blocks at least two actions of GH, the stimulation of tyrosyl phosphorylation of multiple proteins and MAP kinase activation.	cyclo(tyrosyl-tyrosyl)	124-131	growth hormone 1	Homo sapiens	31-33